Nanoparticles in Periodontology and Implant Dentistry: From Mechanisms to Clinical Applications
Nanotechnology holds significant promise in improving dental care, yet there is a need for more reliable clinical studies to validate its effectiveness and safety. ABSTRACT Recent advances in nanotechnology are reshaping the landscape of periodontology and implant dentistry, particularly through the application of nanoparticles (NPs).
Chun Xu +4 more
wiley +1 more source
A membrane‐bound metallo‐endopeptidase from rat kidney hydrolyzing parathyroid hormone [PDF]
Toru Yamaguchi +4 more
openalex +1 more source
Genomic, Proteomic, and Phenotypic Spectrum of Novel O-Sialoglycoprotein Endopeptidase Variant in Four Affected Individuals With Galloway-Mowat Syndrome [PDF]
Malak Alghamdi +19 more
openalex +1 more source
Proteomic Characterization of Grade II Furcation Defects: A Discovery‐Phase Study
This study analyzed the gingival crevicular fluid (GCF) proteome of 35 patients with Grade II furcation defects using the Olink Reveal platform. Comparison with non‐periodontitis sites identified 227 differentially expressed proteins. A machine‐learning pipeline prioritized a 34‐protein signature (including GLIPR1, MME, and IRAG2) that accurately ...
Georgios S. Chatzopoulos +3 more
wiley +1 more source
Proximity‐Induced Transfer of a Mass Tag Enables Direct Profiling of Active Matrix Metalloproteases
A proximity‐induced, mass‐encoded activity‐based protein profiling (ABPP) approach transfers a MALDI‐detectable α‐cyano‐4‐hydroxycinnamic acid (CHCA) tag directly to active proteases. This tag enables the direct, multiplexed, and quantitative detection of enzyme activity in complex proteomes without enrichment or purification.
Lomane Berthy +20 more
wiley +2 more sources
The Discovery of Small Molecule Inhibitors of Neutral Endopeptidase. Structure–Activity Studies on Functionalized Glutaramides [PDF]
Graham N. Maw +12 more
openalex +1 more source
Oral Mucositis in Oncopediatric Patients: MTX and MMP‐1, MMP‐8, MMP‐13 Gene Polymorphisms
ABSTRACT Background This study investigates the association between single‐nucleotide polymorphisms (SNPs) in the MMP‐1, MMP‐8, and MMP‐13 genes and the risk of oral mucositis development in paediatric patients with leukaemia and lymphoma who are undergoing methotrexate (MTX) treatment.
Nicole Januário Ribeiro +6 more
wiley +1 more source
IgG Endopeptidase in Highly Sensitized Patients Undergoing Transplantation [PDF]
openalex +1 more source
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin +6 more
wiley +1 more source
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer +4 more
wiley +1 more source

