Results 101 to 110 of about 32,233 (214)

Tumor Plasticity and Microenvironmental Crosstalk as Drivers of Metastasis and Therapy Resistance

MedComm, Volume 7, Issue 8, August 2026.
The graphical abstract is a schematic illustration of the bidirectional crosstalk between tumor plasticity and the tumor microenvironment (TME) in driving metastasis and therapy resistance. Tumor‐intrinsic factors such as genetic mutations and epigenetic reprogramming enable dynamic transitions between epithelial, mesenchymal, and cancer stem cell ...
Gunjan Dagar, Manisha Dagar, Ashna Gupta, Anju Surendranath, Suraja Kumar Das, Mohd Umar Rehmani, Mukesh Tanwar, Sameer Mirza, Muzafar A. Macha, Ammira S. Al‐Shabeeb Akil, Shahab Uddin, Mayank Singh, Ajaz A. Bhat   +12 more
wiley   +1 more source

Embryonic Mediators of Embryo–Uterus Communication, Implantation and Pregnancy

Molecular Reproduction and Development, Volume 93, Issue 8, August 2026.
ABSTRACT Successful reproduction in eutherian mammals requires intimate connections between the embryo and uterus, involving adhesion, attachment and placentation, with or without invasion of the endometrium. The complex dialogue between embryo and uterus involves numerous molecules and pathways.
Keith E. Latham
wiley   +1 more source

Testican‐1‐MMP axis in tumour extracellular matrix (ECM) remodelling: interaction dynamics analysis and an in silico perspective

The Journal of Pathology, Volume 269, Issue 4-5, Page 433-445, August 2026.
Abstract The extracellular matrix (ECM) plays a pivotal role in facilitating tumour development, invasiveness, metastasis, and immunoevasive processes through dynamic ECM remodelling processes. Testican‐1 (SPOCK1), an excretory matricellular proteoglycan, is suggested to exert a role in the facilitation of ECM remodelling processes through interacting ...
Sepideh Youssefi, Kiarash Saleki, Prerna Kadam, Amirreza Mazloomi, Abhik Mukherjee, Lodewijk V Dekker, Abdolrahman S Nateri   +6 more
wiley   +1 more source

Identification of drug repurposing candidates for the treatment of polycystic kidney disease

British Journal of Pharmacology, Volume 183, Issue 16, Page 5082-5101, August 2026.
Background and Purpose Autosomal dominant polycystic kidney disease (ADPKD) is a leading cause of end‐stage renal disease with limited treatment options. Drug repurposing offers a promising strategy to find effective treatments. Experimental Approach We identified birinapant, bardoxolone methyl and salicylic acid as repurposing candidates for ADPKD and
Alina Meyer, Paraskevi Sotiropoulou, Koussai Bouker, Dennis Svedberg, Rebekkah Hammar, Hester Bange, Per Larsson, André Mateus, Daniel R. Dietrich, Per Artursson   +9 more
wiley   +1 more source

Structure and Activity of Class II Lanthipeptides From a Thermophilic Bacterium

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Heterologous coexpression of the lanthipeptide synthetase TlaM from the thermophilic bacterium Thermoactinomyces sp. DSM 45891, with the precursor peptides TlaA1 and TlaA2 in Escherichia coli, resulted in the introduction of four thioether rings in both peptides.
Enleyona Weir, Lingyang Zhu, Wilfred A. van der Donk   +2 more
wiley   +1 more source

Nonsense‐Mediated Decay mRNA Quality Control System Is Essential for Root Development and Efficient Root Nodule Symbiosis in Medicago truncatula

Plant, Cell &Environment, Volume 49, Issue 9, Page 7210-7214, September 2026.
János B. Biró, Csaba Péter, Ágota Domonkos, Zoltán Hegedűs, Lóránt Lakatos, Deepali Rana, Péter Gyula, Dániel Silhavy, Péter Kaló   +8 more
wiley   +1 more source

Antibacterial potential of five phages in controlling Enterococcus faecalis and Enterococcus faecium. [PDF]

Virol J
Tuomala H, Nylund T, Mustonen M, Flod A, Kiljunen S.   +4 more
europepmc   +1 more source

Botulinum neurotoxins: A distinct subclass of SNARE-Cleaving endopeptidases. [PDF]

Anaerobe
Pellett S.
europepmc   +1 more source

Specific role of two NlpC/P60 endopeptidases in cell division and membrane vesicle formation in <i>Deinococcus radiodurans</i>. [PDF]

Curr Res Microb Sci
Kamara T, Martinez G, Eugénie N, Dutertre M, Confalonieri F, Bentchikou E, Servant P.   +6 more
europepmc   +1 more source

Differential endopeptidase requirements during adaptation to changing growth conditions in <i>Vibrio cholerae</i>. [PDF]

Microbiology (Reading)
Rosch K, Basu U, Lei S, Zheng J, van Teeffelen S, Dörr T.   +5 more
europepmc   +1 more source