Results 91 to 100 of about 32,233 (214)

Bacteriophage P22 Virus‐Like Particles as Nanoscale Protein Scaffolds for Plant Synthetic Biology

Plant Biotechnology Journal, EarlyView.
ABSTRACT Advancing the utility of plant synthetic biology requires the continued development of protein engineering tools. Self‐assembling protein compartments, such as virus‐like particles (VLPs), provide versatile scaffolds for synthetic biology. However, few plant‐expressed VLPs have demonstrated broad amenability to protein engineering, restricting
Maxim D. Harding, Mark A. Jackson, Edward K. Gilding, David J. Craik, Frank Sainsbury, Nicole Lawrence   +5 more
wiley   +1 more source

Optimization of whey protein isolate hydrolysis with endopeptidases for production of antioxidant protein hydrolysates

Applied Food Research
Milk proteins are a rich source of bioactive peptides, which can be released by enzymatic hydrolysis. This study optimized the hydrolysis of bovine whey protein isolate using two commercial peptidases (Maxipro® PSP and Maxipro® TNP), aiming to maximize ...
Virgínia Nardy Paiva, Rafaela da Silva Rodrigues, Luis Gustavo Lima Nascimento, Guilherme Lembi Ramalho Maciel, Andressa Fusieger, Cleonice Aparecida Salgado, Evandro Martins, Robson Bruno Dutra Pereira, Solimar Gonçalves Machado, Antônio Fernandes de Carvalho   +9 more
doaj   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

Periodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer, Luigi Nibali, Noha Zoheir, Niki M. Moutsopoulos, Bruno G. Loos   +4 more
wiley   +1 more source

Placental mitochondrial metabolic adaptation maintains cellular energy balance in pregnancy complicated by gestational hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong, Beth J. Allison, Kirsty L. Brain, Olga V. Patey, Youguo Niu, Kimberley J. Botting, Sage G. Ford, Tess A. Garrud, Peter F. B. Wooding, Qiang Lyu, Lin Zhang, Jin Ma, Alice P. Sowton, Katie A. O'Brien, Tereza Cindrova‐Davies, Hong Wa Yung, Graham J. Burton, Andrew J. Murray, Dino A. Giussani   +18 more
wiley   +1 more source

Fibroblast Activation Protein Expression Differs Between Inflamed and Fibrostenotic Inflammatory Bowel Disease

JCC Plus, Volume 1, Issue 5, September 2026.
This study demonstrates that fibroblast activation protein expression is elevated in inflamed and fibrostenotic inflammatory bowel disease, with highest levels in fibrostenotic Crohn's disease. Cellular fibroblast activation protein predominates in inflamed tissues and localises to α‐SMA−PDPN−CD90+ stromal cells. ABSTRACT Background Intestinal fibrosis
Dalia A. Lartey, Bram W. van Os, Bo Jun Ke, Kelly van Wijnbergen, Gert de Hertogh, Luuk J. A. C. Hawinkels, Gianluca Matteoli, Jie Su, Christianne J. Buskens, Jarmilla D. W. van der Bilt, Geert R. A. M. D'Haens, Joep Grootjans, Manon E. Wildenberg, Marieke C. Barnhoorn, Mark Löwenberg   +14 more
wiley   +1 more source

Noncoding RNA Transcripts Based Molecular Phenotyping of MASLD and MASH Patients

Liver International Communications, Volume 7, Issue 3, September 2026.
ABSTRACT Background and Aims Metabolic dysfunction‐associated steatotic liver disease (MASLD) is a progressive hepatic metabolic disorder characterized by excessive fat accumulation in hepatocytes. MASLD can advance to metabolic dysfunction‐associated steatohepatitis (MASH).
Frida M. Delgadillo, Karla Perez, Barbara Yang, Subramanian Dhandayuthapani, Murali M. Yallapu, Subhash C. Chauhan, Enrique I. Ramos, Shrikanth S. Gadad   +7 more
wiley   +1 more source

The important role of matrix metalloproteinases in nematode parasites

Helminthologia, 2014
Azami M., Anvarinejad M., Jamshidian Ghalesefidi M.   +2 more
doaj   +1 more source

DMS‐MaPseq and DREEM Analyses Implicate the Critical Role of RNA Structural Dynamics in Turnip Yellow Mosaic Virus Pathogenicity

Advanced Science, Volume 13, Issue 43, 3 August 2026.
RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu, Changhao Li, Chisimbily Onyia, Xindi Li, Xingxing Yan, Songxiao Zhong, Taerin Oh, Xiuren Zhang   +7 more
wiley   +1 more source

Identification of Prognostic Genes Relevant With the Nuclear Factors of Activated T Cells Based on Transcriptomics in Oral Squamous Cell Carcinoma

Clinical and Experimental Dental Research, Volume 12, Issue 4, August 2026.
ABSTRACT Background It has previously been demonstrated that the nuclear factor of activated T cells (NFAT) is crucial for the development of tumors. Given OSCC's drug resistance and poor outcomes, identifying NFAT‐associated prognostic genes is urgent for better treatment.
Julaiti Tuerxun, Ailimaierdan Ainiwaer, Tairan Ding   +2 more
wiley   +1 more source

Total Protein and 10‐Hydroxy‐2‐Decenoic Acid Content, In Vitro Bioaccessibility, Antibacterial, and Antidiabetic Properties of Royal Jelly Collected at Different Harvesting Times

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
In this study, the total protein content and 10‐hydroxy‐2‐decenoic acid content were determined in royal jelly collected at the 72 and 144 h. In vitro bioaccessibility, antibacterial, and antidiabetic properties of royal jelly collected at the 72 and 144 h were also determined. ABSTRACT Royal jelly has received interest as a functional food.
Eyuel Welelaw, Abera Belay, Tadele Alemu, Teferi Damto, Admasu Addi, Mesfin Getachew Tadesse, Endale Amare, Feriehiwote Weldeyohanis Gebremariam, Ibrahim Ahmed Sherif, Henock Woldemichael Woldemariam   +9 more
wiley   +1 more source