Results 71 to 80 of about 35,058 (249)

Glycan strand cleavage by a lytic transglycosylase, MltD contributes to the expansion of peptidoglycan in Escherichia coli.

open access: yesPLoS Genetics
Peptidoglycan (PG) is a protective sac-like exoskeleton present in most bacterial cell walls. It is a large, covalently crosslinked mesh-like polymer made up of many glycan strands cross-bridged to each other by short peptide chains.
Moneca Kaul   +3 more
doaj   +1 more source

The Cell Elongation Activity of Peptidoglycan Endopeptidases Antagonizes Cell Division in Escherichia Coli

open access: yes, 2020
Cell division in most bacteria is orchestrated by a complex of proteins organized in a ring-shaped structure at midcell known as the divisome or septal ring. In Gram-negative bacteria such as Escherichia coli, this fundamental biological process involves
Truong, Thao
core   +2 more sources

Reduced peptidoglycan synthesis capacity impairs growth of E. coli at high salt concentration

open access: yesmBio
Gram-negative bacteria have a thin peptidoglycan layer between the cytoplasmic and outer membranes protecting the cell from osmotic challenges. Hydrolases of this structure are needed to cleave bonds to allow the newly synthesized peptidoglycan strands ...
Dema Alodaini   +11 more
doaj   +1 more source

Biocatalysts for Peptide Geranylation With Linear and Cyclic Prenyl Groups

open access: yesAngewandte Chemie International Edition, EarlyView.
A combination of genome mining, synthetic biology, and biocatalytic assays revealed enzymes that install linear and cyclized prenyl moieties on ribosomally or chemically synthesized peptides. The promiscuity of both enzymes, while being specific for modification of C‐terminal tryptophans, enables enzymatic access to peptide terpenoid hybrids.
Sarolt Magyari   +10 more
wiley   +1 more source

The development, constitution and functions of the gland apparatus in schistosome cercariae and endopeptidases in its contents

open access: yes, 2023
Flukes of the family Schistosomatidae are blood parasites with two-host life cycles involving aquatic snails as intermediate hosts and avian or mammalian definitive hosts.
Titlová, Lucie
core  

Characterization of the extracellular matrix from human and dog umbilical cords

open access: yesThe Anatomical Record, EarlyView.
Abstract The extracellular matrix is important for maintaining tissue morphogenesis and homeostasis; it can also be used as a biomaterial for the production of biological scaffolds. Particularly, the umbilical cord has shown potential in the production of scaffolds for small‐diameter vessels.
Ana Carla Mendonça   +6 more
wiley   +1 more source

Cumulative Reproductive‐Lactation Burdens Induce a Systemic Immunometabolic Trade‐Off Between Milk Yield and Mammary Health of Dairy Cows

open access: yesAnimal Research and One Health, EarlyView.
A population‐scale longitudinal transcriptomic atlas reveals how lactation stage and parity reshape systemic gene regulation in dairy cows. Multiomics‐inspired analyses uncover dynamic immune and metabolic adaptations that contribute to reproductive longevity and sustained productivity across the bovine lifespan.
Yangyang Shen   +8 more
wiley   +1 more source

Protein digestion in human and rat small intestine: role of new neutral endopeptidases

open access: yes, 1988
Two new phosphoramidon-insensitive neutral endopeptidases were identified and partially characterized in the brush-border membrane of rat and human intestine using N-CBZ-L-Ala-L-Arg-L-Arg-4-methoxy-beta-naphthylamide (Z-Ala-Arg-Arg-MNA) and azocasein or
R. H. Erickson   +4 more
core   +1 more source

Mitochondria‐endoplasmic reticulum organelle glue as maturation promoter for origination/dimensional dual‐cross cardiomyocytes

open access: yesBMEMat, EarlyView.
Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang   +9 more
wiley   +1 more source

Impact of the Degree of Hydrolysis on the Functional Properties of Rice Proteins – A Review

open access: yesCereal Chemistry, EarlyView.
ABSTRACT Background and Objectives Enzymatic hydrolysis has been established as an effective strategy to improve the functional properties of plant proteins. Rice proteins are particularly attractive because of their hypoallergenic nature, high nutritional value, and sustainability, although their technological applications remain limited by their low ...
Poliana Martins de Ávila   +1 more
wiley   +1 more source

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