Results 51 to 60 of about 35,058 (249)

Current Classification of Dermatophytes and Their Pathogenic Factors [PDF]

Journal of Mazandaran University of Medical Sciences
The nomenclature of fungi has undergone significant changes in the last decade. Renaming of fungi has always occurred and will continue, largely due to the influence of molecular methods in taxonomy, diagnosis, and epidemiology. Recently, advancements in
Fatemeh Zahra Ranjbar Golafshani, Saeid Mahdavi Omran, Mojtaba Taghizadeh Armaki, Tahereh Shokohi, Firoozeh Kermani   +4 more
doaj  

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

PROTEIN INHIBITORS SYNTHESISED BY MICROORGANISMS [PDF]

Biotechnologia Acta, 2013
In a review the literature data on protein inhibitors of peptidases synthesised by different types of microorganisms are systematized. It is shown that at the present time on the basis of amino acid sequence homology protein inhibitors are grouped into ...
O. V. Matseliukh, L. D. Varbanets
doaj   +1 more source

Natural Marine and Terrestrial Compounds as Modulators of Matrix Metalloproteinases-2 (MMP-2) and MMP-9 in Alzheimer’s Disease

Pharmaceuticals, 2021
Several studies have reported neuroprotective effects by natural products. A wide range of natural compounds have been investigated, and some of these may play a beneficial role in Alzheimer’s disease (AD) progression. Matrix metalloproteinases (MMPs), a
Lidia Ciccone, Jennifer Vandooren, Susanna Nencetti, Elisabetta Orlandini   +3 more
doaj   +1 more source

Ultrasound‐Activated Nanoinhibitors Blocking the Chemo‐Immune Checkpoint to Overcome Chemotherapy‐Induced Immune Resistance

Advanced Science, EarlyView.
A sono‐responsive chemo‐immune checkpoint nanoinhibitor (Sono‐TT8) co‐delivering TPZ chemotherapy and siXkr8 simultaneously kills tumor cells and blocks PS externalization, reversing chemotherapy‐induced immunosuppression and enhancing antitumor immunity. ABSTRACT Breast cancer features an immunosuppressive tumor microenvironment following chemotherapy
Yunfan Liu, Chier Du, Leilei Zhu, Hongjin An, Shengzhe Hou, Yi Lan, Xuemei Tang, Min Xu, Peng Luo, Hua Teng, Hao Yang, Xun Guo, Jianli Ren, Zhiyi Zhou   +13 more
wiley   +1 more source

Influence of solutes on the inactivation of glutamine synthetase by endopeptidases [PDF]

, 1987
Glutamine synthetase (GS) extracted from young wheat leaves (low endopeptidase activity) is relatively stable at pH 7.5 and 30°C, but is rapidly inactivated when extract from senescing wheat leaves (high endopeptidase activity), purified papain or ...
Fröhlich, V, Feller, Urs
core  

Characterization and Analysis of PHEX Variants in Patients With Hypophosphatemia in Argentina

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Confirming the underlying molecular etiology of hereditary hypophosphatemia (HH) to provide recurrence risk counseling is highly important. Our aims were to describe the detected variants and their distribution across Argentina and to contrast them with published data.
Silvia Ávila, Sara Fernández, Maximiliano Zeballos, María Georgina Poggio   +3 more
wiley   +1 more source

A Dual-Enzyme Amplification Loop for the Sensitive Biosensing of Endopeptidases

, 2023
A rapid and sensitive approach for the detection of endopeptidases via a new analyte-triggered mutual emancipation of linker-immobilized enzymes (AMELIE) mechanism has been developed and demonstrated using a matrix metallopeptidase, a collagenase, as the
Sze Wing Tang (16509935), Chunxi Liu (1993135), Xiaomin Li (207257), Yun Wah Lam (13748), Michael H. W. Lam (16509938), Chuanwen Zhou (11246263)   +5 more
core   +2 more sources

Two Heat Resistant Endopeptidases from Pseudomonas Species with Destabilizing Potential during Milk Storage

, 2019
In the current study, the extracellular endopeptidases from Pseudomonas lundensis and Pseudomonas proteolytica were investigated. The amino acid sequence identity between both endopeptidases is 68%.
Claudia Glück (3836053), Veronika Volk (6194507), Lutz Fischer, Veronika Volk, Sebastian Leptihn, Timo Stressler (435024), Lutz Fischer (435028), Sebastian Leptihn (2189809), Timo Stressler, Claudia Glück, Jacob Ewert, Jacob Ewert (2579452)   +11 more
core   +1 more source

Involvement of Arabidopsis thaliana endoplasmic reticulum KDEL-tailed cysteine endopeptidase 1 (AtCEP1) in powdery mildew-induced and AtCPR5-controlled cell death. [PDF]

PLoS ONE, 2017
Programmed cell death (PCD) is a prerequisite for successful development and it limits the spread of biotrophic pathogens in a rapid hypersensitive response at the site of infection.
Timo Höwing, Marcel Dann, Caroline Hoefle, Ralph Hückelhoven, Christine Gietl   +4 more
doaj   +1 more source