Results 111 to 120 of about 46,663 (296)

Controlling the Precision-Recall Tradeoff in Differential Dependency Network Analysis [PDF]

, 2013
Graphical models have gained a lot of attention recently as a tool for learning and representing dependencies among variables in multivariate data.
Clark, Vincent P., Niculescu-Mizil, Alexandru, Ostroff, Rachel, Oyen, Diane, Stewart, Alex   +4 more
core  

Morphological assessment of different amniotic membrane epithelial denuding techniques [PDF]

, 2007
PURPOSE: To evaluate the morphological features of the amniotic membrane denuded by different techniques. METHODS: Human amniotic membrane was collected at the time of delivery, fixed in increasing concentrations of glycerol (0-50% in DMEM) and preserved
Freymüller-Haapalainen, Edna, Glória, Maria Aparecida da, Gomes, José Álvaro Pereira, Martins, Maria Cristina, Melo, Gustavo Barreto de   +4 more
core   +3 more sources

Endopeptidase-24.5 is not a metallo-endopeptidase [PDF]

Biochemical Journal, 1987
J S, Bond, P E, Butler
openaire   +2 more sources

Omapatrilat, an Angiotensin‐Converting Enzyme and Neutral Endopeptidase Inhibitor, Attenuates EarlyAtherosclerosis in Diabetic and in Nondiabetic Low‐Density Lipoprotein Receptor–Deficient Mice [PDF]

, 2003
Zohar Levy, Ayana Dvir, Aviv Shaish, Svetlana Trestman, Hofit Cohen, Hana Levkovietz, Rita Rhachmani, Mordchai Ravid, Dror Harats   +8 more
openalex   +1 more source

Newly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators

The FEBS Journal, EarlyView.
Autophagy is a cellular degradation process involved in, for example, immune responses to pathogens and neurodegeneration. To identify modulators of autophagy, we developed a microscopy‐based screening assay and identified previously unknown autophagy‐modulating activities in known drugs and natural products from myxobacteria and fungi.
Janine Fichtner, Yan Yan Beer, H. G. Mauricio Ramm, Sabrina Mühlen, Frank Surup, Jennifer Herrmann, Toni Luise Meister, Stephanie Pfaender, Ursula Bilitewski, Mark Brönstrup, Rolf Müller, Manfred Wirth, Eeva‐Liisa Eskelinen, Ingo Schmitz   +13 more
wiley   +1 more source

Immunoglobulin A protease from Sutterella wadsworthensis modifies outcome of infection with Campylobacter jejuni and is associated with microbiome diversity

Gut Microbes
Sutterella wadsworthensis is an enigmatic member of the microbiota, previously reported to be present in healthy humans yet also associated with certain gut diseases and their therapeutic outcomes. Here, we report on S.
Marwan E. Majzoub, Fernando S. Santiago, Shreeya S. Raich, Prakruti Sirigeri, Isidora Simovic, Nicodemus Tedla, Nadeem O. Kaakoush   +6 more
doaj   +1 more source

The metabolism of neuropeptides. Neurokinin A (substance K) is a substrate for endopeptidase-24.11 but not for peptidyl dipeptidase A (angiotensin-converting enzyme) [PDF]

, 1985
Nigel M. Hooper, A J Kenny, Anthony J. Turner   +2 more
openalex   +1 more source

Effect of Qinbai Qingfei Concentrated Pellets on substance P and neutral endopeptidase of rats with post-infectious cough [PDF]

, 2020
Weigang Jia, Wei Wang, Rui Li, Quanyu Zhou, Ying Qu, Yumei Jia, Zhiheng Zhang, Chengwei Wan, Wanwan Zhang   +8 more
openalex   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

The FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Aminobenzosuberone Scaffold as a Modular Chemical Tool for the Inhibition of Therapeutically Relevant M1 Aminopeptidases

Molecules, 2018
The synthesis of racemic substituted 7-amino-5,7,8,9-tetrahydrobenzocyclohepten-6-one hydrochlorides was optimized to enhance reproducibility and increase the overall yield.
Emmanuel Salomon, Marjorie Schmitt, Anil Kumar Marapaka, Athanasios Stamogiannos, Germain Revelant, Céline Schmitt, Sarah Alavi, Isabelle Florent, Anthony Addlagatta, Efstratios Stratikos, Céline Tarnus, Sébastien Albrecht   +11 more
doaj   +1 more source