Results 81 to 90 of about 4,269 (166)

Delta-beta correlation as a candidate endophenotype of social anxiety: A two-generation family study [PDF]

, 2018
Background: Social anxiety disorder (SAD) is characterized by an extreme and intense fear and avoidance of social situations. In this two-generation family study we examined delta-beta correlation during a social performance task as candidate ...
Molen, M.J.W. van der, Melle J.W. van der Molen, Westenberg, P.M., Vliet, I.M. van, Van der Molen, M.J.W., Houwing-Duistermaat, J.J., Irene M. van Vliet, Houwing-Duistermaat, JJ, Westenberg, PM, Harrewijn, A., Jeanine J. Houwing-Duistermaat, Harrewijn, A, Van der Molen, MJW, Anita Harrewijn, Van Vliet, I.M., Van Vliet, IM, P. Michiel Westenberg   +16 more
core   +1 more source

Genetic Determinants of Tau-PET Imaging in Alzheimer’s Disease: A Narrative Review of Genome-Wide and Candidate-Gene Studies

Journal of Imaging
Alzheimer’s disease (AD) is characterized by extracellular β-amyloid (Aβ) plaques and intracellular hyperphosphorylated tau neurofibrillary tangles, with tau pathology correlating more strongly than amyloid pathology with cognitive decline and neuronal ...
Jaskeerat Gujral, Om H. Gandhi, Tejas Bhogale, Amir A. Amanullah, Ashil Srivastava, Shashi B. Singh, Thomas J. Werner, Poul Flemming Høilund-Carlsen, Abass Alavi   +8 more
doaj   +1 more source

Real‐Time Neurochemical Sensing in Zebrafish: Electrochemical and Fluorescent Approaches

Analysis &Sensing, Volume 6, Issue 6, November 2026.
The use of zebrafish has emerged as a powerful approach for real‐time neurochemical measurements. This review highlights recent advances in electrochemical and fluorescent sensing strategies that enable dynamic measurements in live preparations of this complex vertebrate. These complementary approaches provide new insights into neurochemical signaling,
Piyanka Hettiarachchi, Jacob T. Theismann, Michael A. Johnson   +2 more
wiley   +1 more source

Endophenotypes in the personality disorders

Dialogues in Clinical Neuroscience, 2005
The identification of endophenotypes in the personality disorders may provide a basis for the identification of underlying genotypes that influence the traits and dimensions of the personality disorders, as well as susceptibility to major psychiatric illnesses.
openaire   +3 more sources

Amine Metabolism Is Influenced by Dietary Protein Source

Frontiers in Nutrition, 2017
Growth in world population will inevitably leads to increased demand for protein for humans and animals. Protein from insects and blood plasma are being considered as possible alternatives, but more research on their nutritional quality and health ...
Soumya K. Kar, Soumya K. Kar, Alfons J. M. Jansman, Dirkjan Schokker, Leo Kruijt, Amy C. Harms, Amy C. Harms, Jerry M. Wells, Mari A. Smits, Mari A. Smits, Mari A. Smits   +10 more
doaj   +1 more source

Asthma: From Phenotypes to Endotypes—Beyond Type 2 Inflammation

Respirology, Volume 31, Issue 11, Page 1077-1090, November 2026.
ABSTRACT Asthma is a heterogeneous syndrome featuring variable pathophysiology, clinical presentation and treatment response. This review examines a comprehensive endotype‐phenotype framework for asthma assessment with an emphasis on characteristics beyond T2 inflammatory status alone.
Mario Fernando, Gregory G. King
wiley   +1 more source

GABAergic Network Dysregulation in Alcohol Use Disorder: Receptor–Transporter Interactions Driving the Transition From Goal‐Directed to Compulsive Behaviour

Addiction Biology, Volume 31, Issue 11, November 2026.
Astrocytic GAT3 regulates ambient GABA levels in the globus pallidus externus (GPe). Reduced GAT3 function enhances extrasynaptic GABAergic signalling and disrupts subthalamic nucleus (STN) regulation and cortical signal fidelity.ABSTRACTAlcohol use disorder (AUD) is characterized by a shift from controlled, goal‐directed drinking to compulsive ...
Hannah Aranda, Nathan Jones, Humza Haroon, Doo‐Sup Choi   +3 more
wiley   +1 more source

A phenotype- and potency-gated extracellular vesicle allocation hypothesis for autism

Frontiers in Child and Adolescent Psychiatry
Autism is a heterogeneous neurodevelopmental condition for which a single extracellular vesicle (EV) product is unlikely to match every biological context.
Burak Tatlı, İbrahim Kamer
doaj   +1 more source

Executive Function in Autism Spectrum Disorder: History, Theoretical Models, Empirical Findings, and Potential as an Endophenotype

Frontiers in Psychiatry, 2019
This review presents an outline of executive function (EF) and its application to autism spectrum disorder (ASD). The development of the EF construct, theoretical models of EF, and limitations in the study of EF are outlined.
Eleni A. Demetriou, Marilena M. DeMayo, Adam J. Guastella   +2 more
doaj   +1 more source

Sustained attention as a potential endophenotype for bipolar disorder [PDF]

, 2010
Objective: Nowadays, it is accepted that to identify the biological basis of psychiatric illnesses it would be useful to deconstruct them into the most basic manifestations, such as cognitive deficits.
Torrijos, Sergio, Argudo, Isabel, López-Ibor Aliño, Juan José, Barabash Bustelo, Ana, Cabranes Díaz, José Antonio, Sánchez Morla, Eva María, De La Vega Rodríguez, Irene, Vázquez‐Álvarez, Blanca, Ancín, Inés, Bescós, Mará José, Teijeira, C, B. Vázquez-Álvarez, J. L. Santos, I. De La Vega, I. Argudo, I. Ancín, E. M. Sánchez-Morla, M. J. Bescós, J. J. López-Ibor, J. A. Cabranes-Díaz, S. Torrijos, A. Barabash, C. Teijeira   +22 more
core   +1 more source