Results 121 to 130 of about 481,400 (346)

Reduced SERCA Function Preferentially Affects Wnt Signaling by Retaining E-Cadherin in the Endoplasmic Reticulum

Cell Reports, 2019
Summary: Calcium homeostasis in the lumen of the endoplasmic reticulum is required for correct processing and trafficking of transmembrane proteins, and defects in protein trafficking can impinge on cell signaling pathways. We show here that mutations in
Annabelle Suisse, Jessica E. Treisman
doaj  

INTRACISTERNAL GRANULES OF THE ENDOPLASMIC RETICULUM IN THE CRAYFISH OÖCYTE [PDF]

, 1962
H. W. Beams, Richard G. Kessel
openalex   +1 more source

Endoplasmic reticulum stress signals in the tumour and its microenvironment

Nature Reviews. Cancer, 2020
Xi Chen, J. Cubillos-Ruiz
semanticscholar   +1 more source

Preferential Membrane Remodeling on Curved Biointerfaces Induced by Conjugated Oligoelectrolyte

Advanced Materials Interfaces, EarlyView.
This study explores how membrane shape influences the interaction of conjugated oligoelectrolytes (COEs) with lipid bilayers. Using a curved biointerface composed of nanobar arrays and supported lipid bilayers, it is revealed that COE intercalation preferentially remodels curved regions, forming distinct structures. These findings highlight the role of
Xinwen Miao, Samuel Jun Wei Chan, Sian Kang Chong, Xiangfu Guo, James Chin Shing Ho, Atul N. Parikh, Guillermo Carlos Bazan, Wenting Zhao   +7 more
wiley   +1 more source

TMCO1 is upregulated in breast cancer and regulates the response to pro-apoptotic agents in breast cancer cells

Cell Death Discovery
The release of Ca2+ ions from endoplasmic reticulum calcium stores is a key event in a variety of cellular processes, including gene transcription, migration and proliferation.
Alice H. L. Bong, Mélanie Robitaille, Sichun Lin, Amy McCart-Reed, Michael Milevskiy, Stéphane Angers, Sarah J. Roberts-Thomson, Gregory R. Monteith   +7 more
doaj   +1 more source

HYDROLYSIS OF CARBAMOYL PHOSPHATE IN THE ENDOPLASMIC RETICULUM AND NUCLEAR ENVELOPE OF RAT LIVER [PDF]

, 1968
Akira Mizutani, Hajime Fujita
openalex   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

Consequences and Mechanisms of Noise‐Induced Cochlear Synaptopathy and Hidden Hearing Loss, With Focuses on Signal Perception in Noise and Temporal Processing

Advanced Science, EarlyView.
Noise‐induced synaptopathy (NIS) is largely reversible due to self‐repair. NIS and noise‐induced hidden hearing loss are two concepts with similarities and differences. The major hearing deficits in NIHHL are temporal processing disorders. The translation of animal data in NIS studies to humans is hindered by many factors.
Hui Wang, Steven J Aiken, Jian Wang
wiley   +1 more source

Endoplasmic reticulum stress, autophagy, neuroinflammation, and sigma 1 receptors as contributors to depression and its treatment

Neural Regeneration Research
The etiological factors contributing to depression and other neuropsychiatric disorders are largely undefined. Endoplasmic reticulum stress pathways and autophagy are well-defined mechanisms that play critical functions in recognizing and resolving ...
Chika Fujii, Charles F Zorumski, Yukitoshi Izumi   +2 more
doaj   +1 more source

ON THE RELATIONSHIP OF LIVER GLUCOSE-6-PHOSPHATASE TO THE PROLIFERATION OF ENDOPLASMIC RETICULUM IN PHENOBARBITAL INDUCTION [PDF]

, 1966
Sten Orrenius, Jan L. E. Ericsson
openalex   +1 more source