Results 191 to 200 of about 605,400 (330)

The endoplasmic reticulum membrane protein complex (EMC) negatively regulates intestinal homeostasis through the Hippo signaling pathway

, 2022
Zhouhua Li
openalex   +2 more sources

Dual Targeting of Mutant p53 and SNRPD2 via Engineered Exosomes Modulates Alternative Splicing to Suppress Ovarian Cancer

Advanced Science, EarlyView.
Mutant p53 drives oncogenic splicing to promote the progression of ovarian cancer by partnering with the spliceosome factor SNRPD2. Therefore, it is engineered iRGD‐exosomes to co‐deliver siRNAs against both targets. This approach restored tumor‐suppressive mRNA isoforms, effectively enhanced sensitivity to cisplatin, and ultimately blocked tumor ...
Wei Zhao, Qian Hao, Yu Gan, Jing Tong, Xiaodan Chen, Shuran Tan, Ruiwen Ruan, Yingdan Huang, Mingming Cao, Jun Deng, Tao Han, Getao Shi, Bo Gao, Yu Zhang, Xiang Zhou   +14 more
wiley   +1 more source

The role of bHLH-PAS transcription factors in endoplasmic reticulum stress. [PDF]

Front Mol Biosci
Krauze I, Krzystek-Korpacka M, Maciejewska K, Greb-Markiewicz B.   +3 more
europepmc   +1 more source

High affinity ryanodine binding sites in rat liver endoplasmic reticulum [PDF]

, 1990
Varda Shoshan‐Barmatz
openalex   +1 more source

Tumor suppressive Ca2+ signaling is driven by IP3 receptor fitness [PDF]

, 2017
Bultynck, G, Campanella, M
core   +3 more sources

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

Binary division of plastids involves endoplasmic reticulum mediation. [PDF]

J Exp Bot
Ghosh PP, Kunjumon TK, Mathur J.
europepmc   +1 more source

ABCG1 PLAYS AN IMPORTANT ROLE IN KEEPING ENDOTHELIAL FUNCTION ASSOCIATED WITH ENDOPLASMIC RETICULUM STRESS [PDF]

, 2012
Xuejiahong Xuejiahong
openalex   +1 more source

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

nERdy: network analysis of endoplasmic reticulum dynamics. [PDF]

Commun Biol
Samudre A, Gao G, Cardoen B, Joshi B, Nabi IR, Hamarneh G.   +5 more
europepmc   +1 more source