Results 191 to 200 of about 481,400 (346)

Mitochondria-Associated Endoplasmic Reticulum Membranes in Human Health and Diseases. [PDF]

open access: yesMedComm (2020)
Liu Y   +10 more
europepmc   +1 more source

Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease.

open access: yesJournal of Hepatology, 2018
C. Lebeaupin   +5 more
semanticscholar   +1 more source

EBBP‐Mediated Integrated Stress Response Attenuates Anthracycline‐Induced Cardiotoxicity by Inhibiting the Ferroptosis of Cardiomyocytes

open access: yesAdvanced Science, EarlyView.
EBBP expression is significantly upregulated in DOX‐treated cardiomyocytes. Mechanistically, EBBP interacts with GRP78 to mediate K63‐linked ubiquitination, thereby attenuating the inhibitory GRP78‐PERK interaction and triggering activation of the PERK‐mediated integrated stress response (ISR).
Zilong Chen   +9 more
wiley   +1 more source

The interplay between endoplasmic reticulum stress and inflammation in multiple sclerosis. [PDF]

open access: yesSci Rep
Maghbooli Z   +4 more
europepmc   +1 more source

Endoplasmic Reticulum-Mitochondrial Contactology: Structure and Signaling Functions.

open access: yesTrends in Cell Biology, 2018
G. Csordás, D. Weaver, G. Hajnóczky
semanticscholar   +1 more source

Mesencephalic Astrocyte‐Derived Neurotrophic Factor Binds BAX to Preserve Mitochondrial Homeostasis and Energy Metabolism for Relieving Myocardial Hypertrophy

open access: yesAdvanced Science, EarlyView.
MANF in cardiomyocytes interacts with BAX to impede BAX mitochondrial translocation and cytochrome c release, further stabilizing mitochondrial structure and energy supply to relieve myocardial apoptosis and hypertrophy, which indicates MANF as a novel cardioprotective factor to have a promising clinical application for myocardial hypertrophy ...
Dong Wang   +13 more
wiley   +1 more source

Mitochondrial and endoplasmic reticulum calcium homeostasis and cell death.

open access: yesCell Calcium, 2018
Saverio Marchi   +7 more
semanticscholar   +1 more source

Macrophage‐Mediated Transport of Insoluble Indirubin Induces Hepatic Injury During Intestinal Inflammation

open access: yesAdvanced Science, EarlyView.
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu   +9 more
wiley   +1 more source

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