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T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Advances in Endoplasmic Reticulum Stress Research-Insights from the Special Issue "Endoplasmic Reticulum Stress and Apoptosis". [PDF]
Lizák B, Kapuy O.
europepmc +1 more source
Mitochondria-associated endoplasmic reticulum membrane (MAM)-associated calpains system in preeclampsia. [PDF]
Zhang C, Jiang J, Kong H, Ma X, Xin H.
europepmc +1 more source
Mitigating psychological stress-induced cardiac injury: The impact of CB2R agonists on endoplasmic reticulum stress and mitophagy. [PDF]
Ma C, Gai W, Zhang K, Qin C.
europepmc +1 more source
A guide to characterizing the dynamic mitochondria-endoplasmic reticulum contact sites. [PDF]
Diokmetzidou A, Scorrano L.
europepmc +1 more source
Endoplasmic Reticulum Stress Drives VEGF Gene Expression in Monocytic Cells. [PDF]
Bahman F +6 more
europepmc +1 more source
Fe2+ - induced inbibition of gerbil forebrain endoplasmic reticulum Ca2+ - ATPase
Peter Račay +5 more
openalex +1 more source
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Annals of the New York Academy of Sciences, 2007
Abstract: Stress is the imbalance of homeostasis, which can be sensed even at the subcellular level. The stress‐sensing capability of various organelles including the endoplasmic reticulum (ER) has been described. It has become evident that acute or prolonged ER stress plays an important role in many human diseases; especially those involving organs ...
BANHEGYI G +15 more
openaire +3 more sources
Abstract: Stress is the imbalance of homeostasis, which can be sensed even at the subcellular level. The stress‐sensing capability of various organelles including the endoplasmic reticulum (ER) has been described. It has become evident that acute or prolonged ER stress plays an important role in many human diseases; especially those involving organs ...
BANHEGYI G +15 more
openaire +3 more sources

