Results 251 to 260 of about 462,885 (376)

BAP31 represses endoplasmic reticulum stress-mediated apoptosis and alleviates neurodegeneration in Parkinson's disease. [PDF]

Cell Death Dis
Qin Y, Chen Y, Chi M, Jia J, Wang L, Zhao Y, Wang Z, Zhou J, Yao J.   +8 more
europepmc   +1 more source

Endoplasmic Reticulum Stress Induces Hyaluronan Deposition and Leukocyte Adhesion [PDF]

, 2003
Alana K. Majors, Richard C. Austin, Carol A. de la Motte, Reed E. Pyeritz, Vincent Hascall, Sean P. Kessler, Ganes C. Sen, Scott A. Strong   +7 more
openalex   +1 more source

Single‐Cell Dissection of the Biological Function and Molecular Features Underlying the Micropeptide LSMEM1 in Kidney

Advanced Science, EarlyView.
LSMEM1, an evolutionarily conserved micropeptide with extreme hydrophobicity (aliphatic index═113) and dynamic amphiphilicity (GRAVY═0.017), features a strong α‐helical transmembrane anchor (residues 64‐86). Single‐cell analysis reveals its critical role in renal lipid homeostasis.
Peimin Liu, Hong Zhang, Shanzhi Yang, Jiaoqing Li, Danfeng Wu, Haosen Xu, Huan Jiang, Yi Jing, Guoxiang Jin, Ruobing Liu, Ning Fan, Xiaoyan Bai   +11 more
wiley   +1 more source

Identification of Endoplasmic Reticulum Stress-Related Genes in Osteoporosis Pathogenesis. [PDF]

Mediators Inflamm
Zhu Y, Yang X, Lu Y, He J, Liu B, Zhang Y, Zhang Z.   +6 more
europepmc   +1 more source

Mitochondria‐Localized Nestin Protects Mesenchymal Stem Cells from Senescence by Maintaining Cristae Structure and Function

Advanced Science, EarlyView.
Nestin localizes to the mitochondrial IMS through its MTS and the TOM20 import machinery. Within the mitochondria, Nestin interacts with Mic60 via its C‐terminal Tail3 domain. Loss of mitochondrial Nestin disrupts cristae architecture, leading to mitochondrial swelling, bioenergetic dysfunction, and ultimately the senescence of hMSCs.
Hainan Chen, Jinsi Chen, Li Huang, Xingqiang Lai, Kai Xia, Qiying Lu, Bingbing Xie, Yinong Huang, Yuan Qiu, Tao Wang, Jianqi Feng, Yuanjun Guan, Siyao Che, Jiancheng Wang, Andy Peng Xiang   +14 more
wiley   +1 more source

Hhatl Reduces Apoptosis of Müller Cells in Diabetic Retinopathy by Relieving Endoplasmic Reticulum Stress. [PDF]

Int J Endocrinol
Qin J, Wang Y, Cao H, Liu B, Kan X, Wu L.   +5 more
europepmc   +1 more source

Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilization

, 2002
Patricia Boya, Isabel Cohen, Naoufal Zamzami, Helena L.A. Vieira, Guido Kroemer   +4 more
openalex   +1 more source

Activation of endoplasmic reticulum stress signaling pathway is associated with neuronal degeneration in MoMuLV-ts1-induced spongiform encephalomyelopathy [PDF]

, 2004
Hun-Taek Kim, Kara Waters, George Stoica, Wenan Qiang, Na Liu, Virginia L. Scofield, P.K.Y. Wong   +6 more
openalex   +1 more source

Alternative Models for Anticancer Drug Discovery From Natural Products Using Binary Tumor‐Microenvironment‐on‐a‐Chip

Advanced Science, EarlyView.
This study presents a binary tumor‐microenvironment‐on‐a‐chip (T‐MOC) system incorporating multicellular tumor spheroids (MCTs) as an alternative preclinical platform to evaluate the efficacy of anticancer natural products. The T‐MOC model reproduces in vivo drug delivery barriers and physiological conditions, enabling morphological analysis to predict
Youngwon Kim, Si Hyeon Chae, Dahae Lee, Bum Soo Lee, Jiseok Lim, Hyo‐Il Jung, Ki Hyun Kim, Bongseop Kwak   +7 more
wiley   +1 more source

Control of Tumor Suppressor p53 Function by Endoplasmic Reticulum Stress [PDF]

, 2004
Like Qu, Antonis E. Koromilas
openalex   +1 more source