Results 271 to 280 of about 230,735 (311)

Identification and analysis of endoplasmic reticulum stress-related genes in neuroblastoma and construction of a prognostic gene signature. [PDF]

Transl Cancer Res
Lu W, Zhou R, Yue Y, Ying J, Xiong T, Tang J, Shi J, Wang H, Zhang L, Ruan T.   +9 more
europepmc   +1 more source

Investigating the Role of Type I Interferon Signaling on Muscle Disease Using Mouse Models

Arthritis &Rheumatology, EarlyView.
Objective Dysregulated type I interferon (IFN) signaling contributes to autoimmune myositis pathogenesis. We investigated the therapeutic effects of JAK inhibitors in two mouse models. We also examined how type I IFNs affect muscle vasculature. Methods Myositis was induced in major histocompatibility complex class I double transgenic ([TRE‐H‐2Kb (H ...
Rita Spathis, Sabrina Narvesen, Deeva Robles Kuriplach, Karen Huang, Teja Sundar, Elizabeth Bagley, Joanna Parkes, Xinyu Jia, Nandhana Sudhan, Alfredo Guzman, Kanneboyina Nagaraju, Melissa Morales   +11 more
wiley   +1 more source

Deciphering the interplay between hypoxia, angiogenesis, and endoplasmic reticulum stress in carcinogenesis: A narrative review. [PDF]

World J Exp Med
Bhardwaj S, Pandey S, Ghosh DK, Sharma T, Jain BP.   +4 more
europepmc   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

Arthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento da Conceicao, Neelanjan Vishnu, Shankara N. Varadarajan, Venugopal R. Bovilla, Rajender K. Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Weight Loss During Obesity Provokes Asparaginase-Associated Liver Steatosis and Endoplasmic Reticulum Stress. [PDF]

FASEB J
Bhavsar CT, Zalma BA, Tomoo K, Zhang Y, Lopez EM, Mirek ET, Dixon JL, Henderson GC, Wek RC, Anthony TG.   +9 more
europepmc   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

The role of bHLH-PAS transcription factors in endoplasmic reticulum stress. [PDF]

Front Mol Biosci
Krauze I, Krzystek-Korpacka M, Maciejewska K, Greb-Markiewicz B.   +3 more
europepmc   +1 more source

Machine-learning assisted subclassification of glioblastoma by developing an endoplasmic reticulum stress-related methylation signature. [PDF]

Front Oncol
Zhao J, Li M, Pu X, Guo Y.
europepmc   +1 more source

Integrin β3 Promotes Retinal Neovascularization via Endoplasmic Reticulum Stress-Mediated Endothelial Cell Senescence. [PDF]

Invest Ophthalmol Vis Sci
Qian Y, Song Y, Ma J.
europepmc   +1 more source

Obesity as a Determinant of Periodontal Therapy Outcomes: Insights on Oxidative and Endoplasmic Reticulum Stress Pathways. [PDF]

Int Dent J
Hermenejildo J, Pelechá-Salvador M, Fernández-Reyes M, Perea-Galera L, Hernández-López OA, Tadeo-Morant E, Silvestre-Rangil J, Rovira-Llopis S, Morillas C, Silvestre FJ, Víctor VM, López-Domènech S, Rocha M.   +12 more
europepmc   +1 more source