Results 261 to 270 of about 462,885 (376)

Decoy Extracellular Vesicles Overcome Triple‐Negative Breast Cancer Heterogeneity via Membrane‐Cytoplasm‐Mitochondria Cascade Targeting

open access: yesAdvanced Science, EarlyView.
siT/MOF@EVs overcome TNBC heterogeneity through a tumor cell membrane–cytoplasm–mitochondria cascade effect, triggering a self‐reinforcing anti‐tumor immune cycle and durable immune memory. The system enables sequential targeting of membrane checkpoints ligands (decoy effect), cytoplasmic siRNA delivery (CSC suppression), and mitochondrial MOF ...
Chuanrong Chen   +8 more
wiley   +1 more source

Xylose Metabolism Perturbation in Yarrowia lipolytica for Efficient Succinic Acid Bioproduction from Lignocellulosic Biomass

open access: yesAdvanced Science, EarlyView.
This study engineers Yarrowia lipolytica to produce succinic acid (SA) from lignocellulosic biomass. Adaptive evolution and multi‐omics analysis identify regulators that alleviate xylose metabolic disorder. Multi‐copy integration of xylose metabolic genes resolves redox imbalances from a futile fatty acid cycle, producing high‐titer SA from corn stover
Yutao Zhong   +7 more
wiley   +1 more source

The Role of Endoplasmic Reticulum Stress in the Development of Periodontitis-From Experimental Cell and Animal Models to Humans. [PDF]

open access: yesInt J Mol Sci
Gawlak-Socka S   +5 more
europepmc   +1 more source

Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3β [PDF]

open access: gold, 2004
Li-Ke Qu   +9 more
openalex   +1 more source

Listeria monocytogenes induces an interferon-enhanced activation of the integrated stress response that is detrimental for resolution of infection in mice [PDF]

open access: yes, 2017
Allagnat   +71 more
core   +2 more sources

The Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress.

open access: yesCurrent molecular medicine, 2016
W. Rozpędek   +5 more
semanticscholar   +1 more source

SP3 and DEP1 Orchestrate Panicle Architecture by Jointly Regulating APO2 Expression in Rice

open access: yesAdvanced Science, EarlyView.
The transcription factor SP3 enhances inflorescence meristem activity and interacts with the cysteine‐rich domain of DEP1. This interaction alters DEP1's subcellular localization between the plasma membrane and nucleus, and suppresses SP3‐mediated transcriptional activation of APO2.
Yuexin Liu   +11 more
wiley   +1 more source

Ailanthone induces apoptosis in U-2OS cells through the endoplasmic reticulum stress. [PDF]

open access: yesFront Immunol
Zhang Y   +9 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy