Results 281 to 290 of about 356,983 (328)

Vesicular Transport Mediated by Endoplasmic Reticulum Stress Sensor BBF2H7 Orchestrates Melanin Production During Melanogenesis. [PDF]

Int J Mol Sci
Phan GH, Fujise K, Imaizumi K, Saito A.
europepmc   +1 more source

Mechanisms of Mitochondrial Toxicity and Cytotoxicity Caused by Pseudomonas aeruginosa Pyocyanin in Human Nasal Epithelial Cells

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson, April Park, Yobouet Ines Kouakou, Zoey A. Miller, Nabil F. Darwich, Nithin D. Adappa, James N. Palmer, Ryan M. Carey, Robert J. Lee   +8 more
wiley   +1 more source

Hhatl Reduces Apoptosis of Müller Cells in Diabetic Retinopathy by Relieving Endoplasmic Reticulum Stress. [PDF]

Int J Endocrinol
Qin J, Wang Y, Cao H, Liu B, Kan X, Wu L.   +5 more
europepmc   +1 more source

Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
Yaqiang Hu et al. engineered a pathogenic Sec16a mutant mouse model using CRISPR/Cas9 technology. They observed that the Sec16a mutant mice displayed diminished learning and memory capabilities, along with a limb‐clasping phenotype upon tail suspension.
Yaqiang Hu, Zhiyang Zeng, Xinyu Ming, Shuming Yin, Yuting Guan, Liangcai Gao, Dali Li   +6 more
wiley   +1 more source

Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review). [PDF]

Mol Med Rep
Zhang P, Cui Y, Liu C, Cui C, Zhang S, Zhang Y, Li F.   +6 more
europepmc   +1 more source

Supplementary Figure S4 from The DRD2 antagonist haloperidol mediates autophagy-induced ferroptosis to increase temozolomide sensitivity by promoting endoplasmic reticulum stress in glioblastoma

Linyong Shi, Hanning Chen, Kunxiang Chen, Chengzong Zhong, Chong Song, Yifeng Huang, Tong Wang, Lei Chen, Chiyang Li, Annie Huang, Hong Li, Yuntao Lu   +11 more
openalex   +1 more source

Polydatin alleviates mitochondrial damage and apoptosis of lung epithelial cells by inhibiting toll‐like receptor 4‐dependent macrophage activation in asthma

Animal Models and Experimental Medicine, EarlyView.
The alleviation of asthma by polydatin is dependent on the blockage of the toll‐like receptor 4 (TLR4)/P2X7R synergy in macrophages. The blockage of the TLR4/P2X7R synergy results in decreased release and secretion of interleukin‐1β (IL‐1β) and IL‐18. In epithelial cells, low IL‐1β and IL‐18 levels inhibit mitochondrial damage and apoptosis.
Guangxing Li, Ruobai Liu, Chang Xu, Jianing Yang, Yilan Song, Li Li, Jingzhi Jiang, Liangchang Li, Chongyang Wang, Guanghai Yan   +9 more
wiley   +1 more source

Baicalin Alleviates LPS-Induced Apoptosis of Periodontal Ligament Cells Via Inhibiting Endoplasmic Reticulum Stress. [PDF]

Int Dent J
Abulaiti G, Qin X, Mao J, Zhu G.
europepmc   +1 more source

Supplementary Figure S2 from The DRD2 antagonist haloperidol mediates autophagy-induced ferroptosis to increase temozolomide sensitivity by promoting endoplasmic reticulum stress in glioblastoma

Linyong Shi, Hanning Chen, Kunxiang Chen, Chengzong Zhong, Chong Song, Yifeng Huang, Tong Wang, Lei Chen, Chiyang Li, Annie Huang, Hong Li, Yuntao Lu   +11 more
openalex   +1 more source

Overexpression of mitofusin 2 ameliorates inflammation and oxidative stress in lipopolysaccharide‐induced mastitis model by regulating phosphofurin acidic cluster sorting protein 2

Animal Models and Experimental Medicine, EarlyView.
The interaction between mitofusin 2 (MFN2) and phosphofurin acidic cluster sorting protein 2 regulates the formation of mitochondria‐associated endoplasmic reticulum membranes (MAM). Overexpression of MFN2 can promote the formation of MAMs and inhibit inflammation and oxidative stress response in mammary epithelial cells.
Xiechen Zhou, Yufei Zhang, He Ma, Shoupeng Fu, Juxiong Liu, Wenjin Guo, Xiaofeng Tian, Bingxu Huang   +7 more
wiley   +1 more source