Results 121 to 130 of about 7,208 (294)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

An ESR and ENDOR study of cadmium tellurium:manganese

open access: yes, 2002
Electron spin resonance (ESR) and electron nuclear double resonance (ENDOR) studies have been carried out on CdTe crystals containing Manganese. The hyperfine interactions of CdTe lattice nuclei with ground state donor electrons in the manganese doped ...
Couzin, Nimbus
core   +1 more source

A Q-Band Pulsed ENDOR Spectrometer for the Study of Transition Metal Ion Complexes in Solids

open access: yes, 2020
We describe the design of a pulsed electron nuclear double resonance (ENDOR) spectrometer operating at Q-band frequencies (35 GHz) for studies of transition metal ion complexes in the temperature range between 4.2 and 297 K.
Böttcher R.   +7 more
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Endor 1960 (volume 1, no. 2)

open access: yes, 1960
Endor is a student published literary magazine that aimed to bring artistic expression to Lehigh\u27s campus.

core  

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Endor 1962 (volume 4, no. 1)

open access: yes, 1962
Endor is a student published literary magazine that aimed to bring artistic expression to Lehigh\u27s campus.

core  

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Endor 1960 (volume 2, no. 1)

open access: yes, 1960
Endor is a student published literary magazine that aimed to bring artistic expression to Lehigh\u27s campus.

core  

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