Results 11 to 20 of about 9,566 (262)
Structural Biology of the Arterivirus nsp11 Endoribonucleases [PDF]
Journal of Virology, 2016 ABSTRACT Endoribonuclease (NendoU) is unique and conserved as a major genetic marker in nidoviruses that infect vertebrate hosts. Arterivirus nonstructural protein 11 (nsp11) was shown to have NendoU activity and play essential roles in the viral life cycle.
Manfeng Zhang +7 more
semanticscholar +5 more sources
Processing Endoribonucleases and mRNA Degradation in Bacteria [PDF]
Journal of Bacteriology, 2002 Volume 184, no. 17, p. 4645-4657, 2002. Page 4647, column 1, lines 42-45: The sentence should read “For example, one message in the T7 early polycistronic mRNA, as well as a few late messages, yields increased protein from RNase III cleavage while the others are not affected by such cleavages (41).”
D. Kennell
semanticscholar +4 more sources
Endoribonucleases – enzymes gaining spotlight in mRNA metabolism [PDF]
The FEBS Journal, 2009 The efficient turnover of messenger RNA represents an important mechanism that allows the cell to control gene expression. Until recently, the mechanism of mRNA decay was mainly attributed to exonucleases, comprising enzymes that degrade RNAs from the ends of the molecules.
Wai Ming Li, T. Barnes, Chow H. Lee
semanticscholar +5 more sources
Identification of Small‐Molecule Inhibitors of the XendoU Endoribonucleases Family [PDF]
ChemMedChem, 2011 The XendoU family of enzymes includes several proteins displaying high sequence homology. The members characterized so far are endoribonucleases sharing similar biochemical properties and a common architecture in their active sites.
R. Ragno +5 more
semanticscholar +7 more sources
An assay of ribonuclease H, endoribonucleases, and phosphatases. [PDF]
Proceedings of the National Academy of Sciences, 1976 An assay for ribonuclease H (EC 3.1.4.34) is described which permits the estimation of the number and the type of cleavages produced by the enzyme when acting on the ribo moiety of a DNA-RNA hybrid substrate. With six different homopolymer hybrids tested,
J. G. Starvianopoulos, E. Chargaff
semanticscholar +4 more sources
Ribonucleases J1 and J2: two novel endoribonucleases in B.subtilis with functional homology to E.coli RNase E [PDF]
Nucleic Acids Research, 2005 Many prokaryotic organisms lack an equivalent of RNase E, which plays a key role in mRNA degradation in Escherichia coli. In this paper, we report the purification and identification by mass spectrometry in Bacillus subtilis of two paralogous ...
Bréchemmier-Baey, Dominique +6 more
core +3 more sources
Nature Communications, 2020 Bacterial RNA degradation is typically initiated by endoribonucleases and followed by exoribonucleases. Here the authors report the targetome of endoRNase Y in Streptococcus pyogenes, revealing the interplay between RNase Y and 3′-to-5′ exoribonuclease ...
Laura Broglia +6 more
doaj +2 more sources
RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia
eLife, 2020 In hypoxic stress conditions, glycolysis enzymes assemble into singular cytoplasmic granules called glycolytic (G) bodies. G body formation in yeast correlates with increased glucose consumption and cell survival.
Gregory G Fuller +8 more
doaj +2 more sources
Endoribonucleases associated with RNAs in chick embryos
FEBS Letters, 1979 proteins in hemopoietic rat cells were reported to have RNase activities [ 121. Similarly, an endogeneous endoribonucleolytic activity was found in the 50 S ribosomal subunit of Eschenihia coli [ 131. This paper describes the existence of a RNA-bound cytoplasmic endoribonuclease in chick embryo.
C. Denoya, E. Scodeller, J. L. La Torre
semanticscholar +4 more sources
Role of Dicer-Dependent RNA Interference in Regulating Mycoparasitic Interactions
Microbiology Spectrum, 2021 Dicer-like proteins (DCLs) play a vital role in RNA interference (RNAi), by cleaving RNA filament into small RNAs. Although DCL-mediated RNAi can regulate interspecific communication between pathogenic/mutualistic organisms and their hosts, its role in ...
Edoardo Piombo +7 more
doaj +2 more sources