Results 11 to 20 of about 5,849 (189)
Endoribonuclease activity associated with animal RNA viruses [PDF]
A specific endoribonucleolytic activity was detected when detergent-lysed vesicular stomatitis of Sendai virus was incubated with the precursor to Escherichia coli tRNA Tyr. The cleavage products produced and the characteristics of the reaction were similar to those previously reported for human KB cell RNase NU.
Daniel Kolakofsky, Sidney Altman
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Characterization of MazF-Mediated Sequence-Specific RNA Cleavage in Pseudomonas putida Using Massive Parallel Sequencing. [PDF]
Under environmental stress, microbes are known to alter their translation patterns using sequence-specific endoribonucleases that we call RNA interferases. However, there has been limited insight regarding which RNAs are specifically cleaved by these RNA
Tatsuki Miyamoto +4 more
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Fifty Shades of Erns: Innate Immune Evasion by the Viral Endonucleases of All Pestivirus Species
The genus Pestivirus, family Flaviviridae, includes four historically accepted species, i.e., bovine viral diarrhea virus (BVDV)-1 and -2, classical swine fever virus (CSFV), and border disease virus (BDV).
Elena de Martin, Matthias Schweizer
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Overview of the Leishmaniavirus endoribonuclease and functions of other endoribonucleases affecting viral gene expression [PDF]
Leishmaniaviruses (LRV) are double-stranded RNA viruses that persistently infect some strains of the protozoan parasite Leishmania. The identification of a short viral RNA transcript led to our discovery of an endoribonuclease activity of the LRV capsid protein.
Kyle J. MacBeth, Jean L. Patterson
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Alu retrotransposons belong to the class of short interspersed nuclear elements (SINEs). Alu RNA is abundant in cells and its repetitive structure forms double-stranded RNAs (dsRNA) that activate dsRNA sensors and trigger innate immune responses with ...
Thomas M. Aune +5 more
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Colicin E3: A Unique Endoribonuclease [PDF]
The question of whether or not a cellular ribonuclease is involved in the cleavage of 16S ribosomal RNA by colicin E3 was investigated. For this purpose ribosomes from strains devoid of some ribonucleases or ribosomes in which ribonucleases had been inactivated by heat or removed by extensive washings were used for the colicin reaction.
B, Meyhack, I, Meyhack, D, Apirion
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Bacterial RNA degradation is typically initiated by endoribonucleases and followed by exoribonucleases. Here the authors report the targetome of endoRNase Y in Streptococcus pyogenes, revealing the interplay between RNase Y and 3′-to-5′ exoribonuclease ...
Laura Broglia +6 more
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T2 ribonucleases are endoribonucleases that are found in every organism and that carry out important biological functions. In plants, T2 ribonucleases are organized into multi-gene families, and each member is thought to have a specific function. In this
Mercedes Diaz-Baena +3 more
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Substrate specificity of human MCPIP1 endoribonuclease [PDF]
AbstractMCPIP1, also known as Regnase-1, is a ribonuclease crucial for regulation of stability of transcripts related to inflammatory processes. Here, we report that MCPIP1 acts as an endonuclease by degrading several stem-loop RNA structures and single-stranded RNAs.
Mateusz Wilamowski +3 more
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RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia
In hypoxic stress conditions, glycolysis enzymes assemble into singular cytoplasmic granules called glycolytic (G) bodies. G body formation in yeast correlates with increased glucose consumption and cell survival.
Gregory G Fuller +8 more
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