The Lepidopteran endoribonuclease-U domain protein P102 displays dramatically reduced enzymatic activity and forms functional amyloids [PDF]
, 2014 Hemocytes of Heliothis virescens (F.) (Lepidoptera, Noctuidae) larvae produce a protein, P102, with a putative endoribonuclease-U domain. In previous works we have shown that P102 is involved in Lepidopteran immune response by forming amyloid fibrils ...
Falabella, P. +7 more
core +1 more source
Regulation of RNase E during the UV stress response in the cyanobacterium Synechocystis sp. PCC 6803
mLife, 2023 Endoribonucleases govern the maturation and degradation of RNA and are indispensable in the posttranscriptional regulation of gene expression. A key endoribonuclease in Gram‐negative bacteria is RNase E.
Satoru Watanabe +10 more
doaj +1 more source
Structure, Evolution, and Functions of Bacterial Type III Toxin-Antitoxin Systems. [PDF]
, 2016 Toxin-antitoxin (TA) systems are small genetic modules that encode a toxin (that targets an essential cellular process) and an antitoxin that neutralises or suppresses the deleterious effect of the toxin.
Chai, Ray +4 more
core +3 more sources
Impact of alternative carbon sources and antifungal treatment on Candida glabrata biofilms transcription profile [PDF]
, 2016 Candida glabrata is considered a major opportunistic fungal pathogen of humans and has emerged as a leading cause of nosocomial fungal infections. The capacity of this yeast species to cause infections is dependent on the ability to grow within the human
Alves, Rosana +8 more
core +1 more source
Characterization of Echinostoma cinetorchis endoribonuclease, RNase H [PDF]
The Korean Journal of Parasitology, 2017 Echinostoma cinetorchis is an oriental intestinal fluke causing significant pathological damage to the small intestine. The aim of this study was to determine a full-length cDNA sequence of E. cinetorchis endoribonuclease (RNase H; EcRNH) and to elucidate its molecular biological characters.
Lim, Sung-Bin +9 more
openaire +2 more sources
Role of Dicer-Dependent RNA Interference in Regulating Mycoparasitic Interactions
Microbiology Spectrum, 2021 Dicer-like proteins (DCLs) play a vital role in RNA interference (RNAi), by cleaving RNA filament into small RNAs. Although DCL-mediated RNAi can regulate interspecific communication between pathogenic/mutualistic organisms and their hosts, its role in ...
Edoardo Piombo +7 more
doaj +1 more source
Iron Deprivation in Synechocystis : Inference of Pathways, Non-coding RNAs, and Regulatory Elements from Comprehensive Expression Profiling [PDF]
, 2012 Iron is an essential cofactor in many metabolic reactions. Mechanisms controlling iron homeostasis need to respond rapidly to changes in extracellular conditions, but they must also keep the concentration of intracellular iron under strict control to ...
Barreira, L +6 more
core +2 more sources
A general approach to high-yield biosynthesis of chimeric RNAs bearing various types of functional small RNAs for broad applications. [PDF]
, 2015 RNA research and therapy relies primarily on synthetic RNAs. We employed recombinant RNA technology toward large-scale production of pre-miRNA agents in bacteria, but found the majority of target RNAs were not or negligibly expressed. We thus developed a
Chen, Qiu-Xia +4 more
core +2 more sources
Global regulatory functions of the Staphylococcus aureus endoribonuclease III in gene expression. [PDF]
PLoS Genetics, 2012 RNA turnover plays an important role in both virulence and adaptation to stress in the Gram-positive human pathogen Staphylococcus aureus. However, the molecular players and mechanisms involved in these processes are poorly understood.
Efthimia Lioliou +7 more
doaj +1 more source
Evidence that autophagy, but not the unfolded protein response, regulates the expression of IL-23 in the gut of patients with ankylosing spondylitis and subclinical gut inflammation. [PDF]
, 2014 OBJECTIVES: Interleukin (IL)-23 has been implicated in the pathogenesis of ankylosing spondylitis (AS). The aim of the study was to clarify the mechanisms underlying the increased IL-23 expression in the gut of AS patients.
Accardo Palumbo,A +9 more
core +1 more source