The Continuing Story of Endoribonuclease III
Microbial Physiology, 2004 Endoribonuclease III (RNase III) plays an important role in the processing of rRNA and mRNAs. It is timely to summarize the most relevant insights obtained during the last years stemming from RNase III. With this aim, the present mini-review provides a wealth of new information focusing on the distribution and architecture of RNase III, substrate ...
Djamel, Drider, Ciarán, Condon
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Global analyses of small interfering RNAs derived from Bamboo mosaic virus and its associated satellite RNAs in different plants. [PDF]
PLoS ONE, 2010 BACKGROUND: Satellite RNAs (satRNAs), virus parasites, are exclusively associated with plant virus infection and have attracted much interest over the last 3 decades.
Kuan-Yu Lin +8 more
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Molecular mechanisms of CRISPR-mediated microbial immunity [PDF]
, 2013 Bacteriophages (phages) infect bacteria in order to replicate and burst out of the host, killing the cell, when reproduction is completed. Thus, from a bacterial perspective, phages pose a persistent lethal threat to bacterial populations.
Giedrius Gasiunas +2 more
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Functional plasticity of antibacterial EndoU toxins. [PDF]
, 2018 Bacteria use several different secretion systems to deliver toxic EndoU ribonucleases into neighboring cells. Here, we present the first structure of a prokaryotic EndoU toxin in complex with its cognate immunity protein.
Eschenfeldt, William H +11 more
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Fragmentation of tRNA in Phytophthora infestans asexual life cycle stages and during host plant infection [PDF]
, 2014 The oomycete Phytophthora infestans possesses active RNA silencing pathways, which presumably enable this plant pathogen to control the large numbers of transposable elements present in its 240 Mb genome.
Avrova, Anna +7 more
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Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system [PDF]
, 2013 The ability to artificially control transcription is essential both to the study of gene function and to the construction of synthetic gene networks with desired properties.
Bikard, David +5 more
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Reversible and irreversible inhibitors of coronavirus Nsp15 endoribonuclease
Journal of Biological Chemistry, 2023 The emergence of severe acute respiratory syndrome coronavirus 2, the causative agent of coronavirus disease 2019, has resulted in the largest pandemic in recent history. Current therapeutic strategies to mitigate this disease have focused on the development of vaccines and on drugs that inhibit the viral 3CL protease or RNA-dependent RNA polymerase ...
Jerry Chen +14 more
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The roles of rice microRNAs in rice-Magnaporthe oryzae interaction
Phytopathology Research, 2019 MicroRNAs (miRNAs) are a class of small (20–24 nucleotides (nt) long) non-coding RNAs. One mature miRNA can be transcribed from one or more gene loci known as miRNA genes (MIRs).
Yan Li +6 more
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CRISPR-Cas systems in prokaryotes [PDF]
, 2015 Prokaryotic organisms possess numerous strategies that enable survival in hostile conditions. Among others, these conditions include the invasion of foreign nucleic acids such as bacteriophages and plasmids.
Burmistrz, Michał, Pyrć, Krzysztof
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Evolutionary Origins of Two-Barrel RNA Polymerases and Site-Specific Transcription Initiation [PDF]
, 2017 Evolutionary-related multisubunit RNA polymerases (RNAPs) carry out RNA synthesis in all domains life. Although their catalytic cores and fundamental mechanisms of transcription elongation are conserved, the initiation stage of the transcription cycle ...
Blombach, F, Fouqueau, T, Werner, F
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