Results 21 to 30 of about 5,581 (192)

Molecular basis for the calcium-dependent activation of the ribonuclease EndoU [PDF]

Nature Communications
Ribonucleases (RNases) are ubiquitous enzymes that process or degrade RNA, essential for cellular functions and immune responses. The EndoU-like superfamily includes endoribonucleases conserved across bacteria, eukaryotes, and certain viruses, with an ...
Florian Malard, Kristen Dias, Margaux Baudy, Stéphane Thore, Brune Vialet, Philippe Barthélémy, Sébastien Fribourg, Fedor V. Karginov, Sébastien Campagne   +8 more
doaj   +2 more sources

A Novel Method to Isolate RNase MRP Using RNA Streptavidin Aptamer Tags

Bio-Protocol, 2023
Interactions between RNA-binding proteins and RNA molecules are at the center of multiple biological processes. Therefore, accurate characterization of the composition of ribonucleoprotein complexes (RNPs) is crucial.
Violette Charteau, Merel Derksen, Ger Pruijn   +2 more
doaj   +1 more source

The effect of two ribonucleases on the production of Shiga toxin and stx-bearing bacteriophages in Enterohaemorrhagic Escherichia coli

Scientific Reports, 2021
Enterohaemorrhagic Escherichia coli (EHEC) comprise a group of intestinal pathogens responsible for a range of illnesses, including kidney failure and neurological compromise.
Patricia B. Lodato
doaj   +1 more source

Fifty Shades of E^rns: Innate Immune Evasion by the Viral Endonucleases of All Pestivirus Species

Viruses, 2022
The genus Pestivirus, family Flaviviridae, includes four historically accepted species, i.e., bovine viral diarrhea virus (BVDV)-1 and -2, classical swine fever virus (CSFV), and border disease virus (BDV).
Elena de Martin, Matthias Schweizer
doaj   +1 more source

Using nucleolytic toxins as restriction enzymes enables new RNA applications. [PDF]

Nucleic Acids Res
Over the past five decades, DNA restriction enzymes have revolutionized biotechnology. While these enzymes are widely used in DNA research and DNA engineering, the emerging field of RNA and mRNA therapeutics requires sequence-specific RNA ...
Rothweiler U, Gundesø SE, Mikalsen EW, Svenning S, Singh M, Combes F, Pettersson FJ, Mangold A, Piotrowski Y, Schwab F, Lanes O, Striberny BK.   +11 more
europepmc   +2 more sources

Alu RNA Structural Features Modulate Immune Cell Activation and A-to-I Editing of Alu RNAs Is Diminished in Human Inflammatory Bowel Disease

Frontiers in Immunology, 2022
Alu retrotransposons belong to the class of short interspersed nuclear elements (SINEs). Alu RNA is abundant in cells and its repetitive structure forms double-stranded RNAs (dsRNA) that activate dsRNA sensors and trigger innate immune responses with ...
Thomas M. Aune, Thomas M. Aune, John T. Tossberg, Rachel M. Heinrich, Krislyn P. Porter, Philip S. Crooke   +5 more
doaj   +1 more source

RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia

eLife, 2020
In hypoxic stress conditions, glycolysis enzymes assemble into singular cytoplasmic granules called glycolytic (G) bodies. G body formation in yeast correlates with increased glucose consumption and cell survival.
Gregory G Fuller, Ting Han, Mallory A Freeberg, James J Moresco, Amirhossein Ghanbari Niaki, Nathan P Roach, John R Yates III, Sua Myong, John K Kim   +8 more
doaj   +1 more source

High Ribonuclease Activity in the Testa of Common Bean Seedlings during Germination: Implication and Characterization of the Ribonuclease T2 PvRNS3

Agronomy, 2023
T2 ribonucleases are endoribonucleases that are found in every organism and that carry out important biological functions. In plants, T2 ribonucleases are organized into multi-gene families, and each member is thought to have a specific function. In this
Mercedes Diaz-Baena, Gregorio Galvez-Valdivieso, Elena Delgado-Garcia, Pedro Piedras   +3 more
doaj   +1 more source

Sinorhizobium meliloti RNase III: Catalytic Features and Impact on Symbiosis

Frontiers in Genetics, 2018
Members of the ribonuclease (RNase) III family of enzymes are metal-dependent double-strand specific endoribonucleases. They are ubiquitously found and eukaryotic RNase III-like enzymes include Dicer and Drosha, involved in RNA processing and RNA ...
Margarida Saramago, Marta Robledo, Rute G. Matos, José I. Jiménez-Zurdo, Cecília M. Arraiano   +4 more
doaj   +1 more source

Colicin E3: A Unique Endoribonuclease [PDF]

Proceedings of the National Academy of Sciences, 1973
The question of whether or not a cellular ribonuclease is involved in the cleavage of 16S ribosomal RNA by colicin E3 was investigated. For this purpose ribosomes from strains devoid of some ribonucleases or ribosomes in which ribonucleases had been inactivated by heat or removed by extensive washings were used for the colicin reaction.
B, Meyhack, I, Meyhack, D, Apirion
openaire   +2 more sources