Impact of alternative carbon sources and antifungal treatment on Candida glabrata biofilms transcription profile [PDF]
Candida glabrata is considered a major opportunistic fungal pathogen of humans and has emerged as a leading cause of nosocomial fungal infections. The capacity of this yeast species to cause infections is dependent on the ability to grow within the human
Alves, Rosana+8 more
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Identification of small RNAs abundant in Burkholderia cenocepacia biofilms reveal putative regulators with a potential role in carbon and iron metabolism [PDF]
Small RNAs play a regulatory role in many central metabolic processes of bacteria, as well as in developmental processes such as biofilm formation. Small RNAs of Burkholderia cenocepacia, an opportunistic pathogenic beta-proteobacterium, are to date not ...
Coenye, Tom+2 more
core +3 more sources
Characterization of Echinostoma cinetorchis endoribonuclease, RNase H [PDF]
Echinostoma cinetorchis is an oriental intestinal fluke causing significant pathological damage to the small intestine. The aim of this study was to determine a full-length cDNA sequence of E. cinetorchis endoribonuclease (RNase H; EcRNH) and to elucidate its molecular biological characters.
Sung-Bin Lim+9 more
openaire +2 more sources
Reversible and irreversible inhibitors of coronavirus Nsp15 endoribonuclease
The emergence of severe acute respiratory syndrome coronavirus 2, the causative agent of coronavirus disease 2019, has resulted in the largest pandemic in recent history. Current therapeutic strategies to mitigate this disease have focused on the development of vaccines and on drugs that inhibit the viral 3CL protease or RNA-dependent RNA polymerase ...
Jerry Chen+14 more
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Processing Endoribonucleases and mRNA Degradation in Bacteria [PDF]
Volume 184, no. 17, p. 4645-4657, 2002. Page 4647, column 1, lines 42-45: The sentence should read “For example, one message in the T7 early polycistronic mRNA, as well as a few late messages, yields increased protein from RNase III cleavage while the others are not affected by such cleavages (41).”
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Degradation of RNA in bacteria: comparison of mRNA and stable RNA [PDF]
Degradation of RNA plays a central role in RNA metabolism. In recent years, our knowledge of the mechanisms of RNA degradation has increased considerably with discovery of the participating RNases and analysis of mutants affected in the various ...
Deutscher, Murray P.
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Activation of an Endoribonuclease by Non-intein Protein Splicing [PDF]
The Chlamydomonas reinhardtii chloroplast-localized poly(A)-binding protein RB47 is predicted to contain a non-conserved linker (NCL) sequence flanked by highly conserved N- and C-terminal sequences, based on the corresponding cDNA. RB47 was purified from chloroplasts in association with an endoribonuclease activity; however, protein sequencing failed ...
Stephen J. Campbell, David B. Stern
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The Tumor Marker Human Placental Protein 11 Is an Endoribonuclease [PDF]
Human PP11 (placental protein 11) was previously described as a serine protease specifically expressed in the syncytiotrophoblast and in numerous tumor tissues. Several PP11-like proteins were annotated in distantly related organisms, such as worms and mammals, suggesting their involvement in evolutionarily conserved processes.
Pietro Laneve+8 more
openaire +6 more sources
DiRiboPred: A Web Tool for Classification and Prediction of Ribonucleases [PDF]
Ribonuclease [commonly abbreviated RNase] is a type of nuclease that catalyzes the degradation of RNA into smaller components and can be divided into endoribonucleases and exoribonucleases.
Dr. bhasker pant, k.r. pardasani
core +3 more sources
Plant RNAi: How aViral Silencing Suppressor Inactivates siRNA [PDF]
The three-dimensional structure of an siRNA bound to the tombusvirus p19 protein – a suppressor of gene silencing – provides a first glimpse into how plant viruses can defeat their host's anti-viral RNAi ...
Zamore, Phillip D.
core +1 more source