Results 31 to 40 of about 5,849 (189)

Role of Dicer-Dependent RNA Interference in Regulating Mycoparasitic Interactions

Microbiology Spectrum, 2021
Dicer-like proteins (DCLs) play a vital role in RNA interference (RNAi), by cleaving RNA filament into small RNAs. Although DCL-mediated RNAi can regulate interspecific communication between pathogenic/mutualistic organisms and their hosts, its role in ...
Edoardo Piombo, Ramesh R. Vetukuri, Anders Broberg, Pruthvi B. Kalyandurg, Sandeep Kushwaha, Dan Funck Jensen, Magnus Karlsson, Mukesh Dubey   +7 more
doaj   +1 more source

Global regulatory functions of the Staphylococcus aureus endoribonuclease III in gene expression. [PDF]

PLoS Genetics, 2012
RNA turnover plays an important role in both virulence and adaptation to stress in the Gram-positive human pathogen Staphylococcus aureus. However, the molecular players and mechanisms involved in these processes are poorly understood.
Efthimia Lioliou, Cynthia M Sharma, Isabelle Caldelari, Anne-Catherine Helfer, Pierre Fechter, François Vandenesch, Jörg Vogel, Pascale Romby   +7 more
doaj   +1 more source

Global analyses of small interfering RNAs derived from Bamboo mosaic virus and its associated satellite RNAs in different plants. [PDF]

PLoS ONE, 2010
BACKGROUND: Satellite RNAs (satRNAs), virus parasites, are exclusively associated with plant virus infection and have attracted much interest over the last 3 decades.
Kuan-Yu Lin, Chi-Ping Cheng, Bill Chia-Han Chang, Wei-Chi Wang, Ying-Wen Huang, Yun-Shien Lee, Hsien-Da Huang, Yau-Heiu Hsu, Na-Sheng Lin   +8 more
doaj   +1 more source

The Continuing Story of Endoribonuclease III

Microbial Physiology, 2004
Endoribonuclease III (RNase III) plays an important role in the processing of rRNA and mRNAs. It is timely to summarize the most relevant insights obtained during the last years stemming from RNase III. With this aim, the present mini-review provides a wealth of new information focusing on the distribution and architecture of RNase III, substrate ...
Djamel, Drider, Ciarán, Condon
openaire   +2 more sources

The roles of rice microRNAs in rice-Magnaporthe oryzae interaction

Phytopathology Research, 2019
MicroRNAs (miRNAs) are a class of small (20–24 nucleotides (nt) long) non-coding RNAs. One mature miRNA can be transcribed from one or more gene loci known as miRNA genes (MIRs).
Yan Li, John Martin Jerome Jeyakumar, Qin Feng, Zhi-Xue Zhao, Jing Fan, Muhammad Ibrahim Khaskheli, Wen-Ming Wang   +6 more
doaj   +1 more source

Reversible and irreversible inhibitors of coronavirus Nsp15 endoribonuclease

Journal of Biological Chemistry, 2023
The emergence of severe acute respiratory syndrome coronavirus 2, the causative agent of coronavirus disease 2019, has resulted in the largest pandemic in recent history. Current therapeutic strategies to mitigate this disease have focused on the development of vaccines and on drugs that inhibit the viral 3CL protease or RNA-dependent RNA polymerase ...
Jerry Chen, Rabih Abou Farraj, Daniel Limonta, Seyed Amir Tabatabaei Dakhili, Evan M. Kerek, Ashim Bhattacharya, Filip M. Reformat, Ola M. Mabrouk, Benjamin Brigant, Tom A. Pfeifer, Mark T. McDermott, John R. Ussher, Tom C. Hobman, J.N. Mark Glover, Basil P. Hubbard   +14 more
openaire   +2 more sources

Mouse ribonuclease III. cDNA structure, expression analysis, and chromosomal location

BMC Genomics, 2002
Background Members of the ribonuclease III superfamily of double-stranded(ds)-RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells. A human RNase III orthologue has been implicated in
Nicholson Rhonda H, Fortin Kristine R, Nicholson Allen W   +2 more
doaj   +1 more source

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

Advanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang, Hung‐Chun Liao, Po Peng, Wan‐Ling Wu, Kit Man Chai, Mei‐Yu Chen, Guann‐Yi Yu, Tsung‐Hsien Chuang, Hsin‐Wei Chen, Chuang‐Rung Chang, Shih‐Jen Liu   +10 more
wiley   +1 more source

Detection of a fourth orbivirus non-structural protein.

PLoS ONE, 2011
The genus Orbivirus includes both insect and tick-borne viruses. The orbivirus genome, composed of 10 segments of dsRNA, encodes 7 structural proteins (VP1-VP7) and 3 non-structural proteins (NS1-NS3).
Mourad Belhouchet, Fauziah Mohd Jaafar, Andrew E Firth, Jonathan M Grimes, Peter P C Mertens, Houssam Attoui   +5 more
doaj   +1 more source

Marine n‐3 Polyunsaturated Fatty Acids Mitigate Obesity Traits Through PRDM16‐Driven Gene–Nutrient Interaction and Spatiotemporal Scale Browning Process

Food Frontiers, EarlyView.
This large cohort study of 45,664 participants from the UK Biobank provides strong epidemiological evidence that fish oil use was associated with 12% and 7% lower risks of obesity and high body fat percentage, respectively. Mechanistically, marine n‐3 polyunsaturated fatty acids mitigate obesity traits through PRDM16‐driven gene–nutrient interactions ...
Xiaohui Liu, Haoyu Li, Youyou Zheng, Xiaoqian Chen, Xuzhi Wan, Pan Zhuang, Wei Jia, Jianxin Yao, Haoyin Liu, Hongbo Shi, Xunan Lin, Yu Zhang, Jingjing Jiao   +12 more
wiley   +1 more source