Results 41 to 50 of about 6,098 (159)
Symmetric Development: Transcriptional Regulation of Symmetry Transition in Plants [PDF]
, 2014 SummarySymmetry breaking and re-establishment is an important developmental process that occurs during the development of multicellular organisms. A new report determines that transcription factors regulate a symmetry transition event in plants by ...
Dolan, Liam
core +1 more source
ESSENTIAL MEIOTIC ENDONUCLEASE 1 is required for chloroplast development and DNA repair in rice
Plant Biotechnology Journal, EarlyView.Summary Chloroplast development is fundamental to photosynthesis and plant growth but is sensitive to environmental stress. Chloroplast development and division require genome stability and DNA repair, but the underlying mechanisms have been unclear. Using a forward genetic approach, we identified the striped‐leaf mutant k48 in the rice (Oryza sativa L.
Yanxin Du +5 more
wiley +1 more source
RNA Recognition and Cleavage by the SARS Coronavirus Endoribonuclease
Journal of Molecular Biology, 2006 The emerging disease SARS is caused by a novel coronavirus that encodes several unusual RNA-processing enzymes, including non-structural protein 15 (Nsp15), a hexameric endoribonuclease that preferentially cleaves at uridine residues. How Nsp15 recognizes and cleaves RNA is not well understood and is the subject of this study.
Jingchuan Sun +4 more
openaire +3 more sources
Caenorhabditis elegans RIG-I Homolog Mediates Antiviral RNA Interference Downstream of Dicer-Dependent Biogenesis of Viral Small Interfering RNAs. [PDF]
, 2017 Dicer enzymes process virus-specific double-stranded RNA (dsRNA) into small interfering RNAs (siRNAs) to initiate specific antiviral defense by related RNA interference (RNAi) pathways in plants, insects, nematodes, and mammals.
Gina Broitman-Maduro +10 more
core +3 more sources
Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria
FEBS Open Bio, Volume 15, Issue 6, Page 949-962, June 2025.The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao +4 more
wiley +1 more source
Characterization of the role of ribonucleases in Salmonella small RNA decay [PDF]
, 2007 In pathogenic bacteria, a large number of sRNAs coordinate adaptation to stress and expression of virulence genes. To better understand the turnover of regulatory sRNAs in the model pathogen, Salmonella typhimurium, we have constructed mutants for ...
Afonyushkin +91 more
core +4 more sources
Homodimerisation-independent cleavage of dsRNA by a pestiviral nicking endoribonuclease [PDF]
Scientific Reports, 2018 AbstractThe glycoprotein Erns plays a central role in the biology of the pestivirus bovine viral diarrhea virus (BVDV). This soluble endonuclease mediates the escape from an interferon (IFN) response in the infected fetus, thereby permitting the establishment of persistent infection. Viral single-stranded (ss) and double-stranded (ds) RNA act as potent
Carmela Lussi +2 more
openaire +3 more sources
Post-transcriptional control by bacteriophage T4: mRNA decay and inhibition of translation initiation [PDF]
, 2010 Over 50 years of biological research with bacteriophage T4 includes notable discoveries in post-transcriptional control, including the genetic code, mRNA, and tRNA; the very foundations of molecular biology.
Miller, Eric S, Uzan, Marc
core +3 more sources
Protein Science, Volume 34, Issue 6, June 2025.Abstract Since the emergence of SARS‐CoV‐2 at the end of 2019, the virus has caused significant global health and economic disruptions. Despite the rapid development of antiviral vaccines and some approved treatments such as remdesivir and paxlovid, effective antiviral pharmacological treatments for COVID‐19 patients remain limited. This study explores
Spyros D. Chatziefthymiou +13 more
wiley +1 more source
Identification of Small‐Molecule Inhibitors of the XendoU Endoribonucleases Family [PDF]
ChemMedChem, 2011 AbstractThe XendoU family of enzymes includes several proteins displaying high sequence homology. The members characterized so far are endoribonucleases sharing similar biochemical properties and a common architecture in their active sites. Despite their similarities, these proteins are involved in distinct RNA‐processing pathways in different ...
RAGNO, Rino +5 more
openaire +7 more sources