Results 61 to 70 of about 5,849 (189)

Biochemical Characterization of Emerging SARS-CoV-2 Nsp15 Endoribonuclease Variants [PDF]

, 2022
Isha M. Wilson, Meredith N. Frazier, Jian‐Liang Li, Thomas A. Randall, Robin E. Stanley   +4 more
openalex   +1 more source

Five‐Year (2017–2022) Evolutionary Dynamics of Human Coronavirus OC43 in Southern France Based on Whole Genome Next‐Generation Sequencing

Journal of Medical Virology, Volume 97, Issue 12, December 2025.
ABSTRACT HCoV‐OC43 genomes and their evolution are scarcely studied worldwide and in France, with only 361 genomes available as of October 2023. Here, an in‐house PCR amplification system was implemented to obtain retrospectively by next‐generation sequencing, then analyze HCoV‐OC43 genomes for infections diagnosed with this virus in southern France ...
Hikmat Houmadi, Céline Boschi, Marine Lefebvre, Lorlane Le Targa, Justine Py, Jean‐Christophe Lagier, Lucile Lesage, Jacques Fantini, Aurélie Morand, Bernard La Scola, Philippe Colson   +10 more
wiley   +1 more source

Structural basis for human mitochondrial tRNA maturation

Nature Communications
The human mitochondrial genome is transcribed into two RNAs, containing mRNAs, rRNAs and tRNAs, all dedicated to produce essential proteins of the respiratory chain. The precise excision of tRNAs by the mitochondrial endoribonucleases (mt-RNase), P and Z,
Vincent Meynier, Steven W. Hardwick, Marjorie Catala, Johann J. Roske, Stephanie Oerum, Dimitri Y. Chirgadze, Pierre Barraud, Wyatt W. Yue, Ben F. Luisi, Carine Tisné   +9 more
doaj   +1 more source

Comparative Genomics and Virulence Mechanisms to Identify Genes Related to Mucin O‐Glycan Degradation and Pathogenicity in a Potentially Multidrug‐Resistant Clostridium tertium Strain

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
The comparative genomic analysis provides information about how C. tertium HGMC01 strain cause disease through mucin glycan degradation, colonization, multidrug resistance, and modulation of immune responses. Moreover, this analysis data suggest that this strain interacts with host cells by degrading mucin in the gut, potentially through recognition or
Seonghun Kim, Ji Young Kang, Jung‐Sook Lee   +2 more
wiley   +1 more source

Two Highly Efficient Prime Editing Systems Based on the Csy4 CRISPR Endonuclease

Plant Biotechnology Journal, EarlyView.
Yu Lu, Dexin Qiao, Junya Wang, Wei Sun, Zhenghong Cao, Minhui Lu, Yiping Chai, Yuanyuan Jiang, Cuiping Xin, Xiaohan Liu, Siyun Li, Syeda Leeda Gul, Qi‐Jun Chen   +12 more
wiley   +1 more source

“Fertile” Mutations in SARS‐CoV‐2 RNA More Frequently Occurred in Hairpin Loops That Determine Virus Evolution

APMIS, Volume 133, Issue 12, December 2025.
ABSTRACT RNA hairpins may constitute a foundation of genetic evolution both in viruses and other organisms. Stem‐loops theoretically comprise a stable part, the double‐stranded stem, and a single‐stranded loop allowing evolution. Here we tested for SARS‐CoV‐2 if “fertile” mutations were in loops while mutations in stems were poorly tolerated and rarely
Philippe Colson, Pierre Pontarotti, Jacques Fantini, Anthony Levasseur, Christian Devaux, Didier Raoult   +5 more
wiley   +1 more source

A Rice Endogenous Small RNA‐Binding Protein Improves Prime Editing for Precise Sequence Insertion and Replacement

Plant Biotechnology Journal, EarlyView.
Yinghui Dong, Fei Su, Hailin Xie, Sinan Zhang, Meng Jia, Chunyu Zou, Mugui Wang, Jian‐Kang Zhu   +7 more
wiley   +1 more source

Protection of germline immortality by the soma via a secreted endoribonuclease

, 2021
Wenjing Qi, Fan Xu, Thomas Heimbucher, Ralf Baumeister   +3 more
openalex   +1 more source

The secreted endoribonuclease ENDU-2 from the soma protects germline immortality in C. elegans [PDF]

, 2021
Wenjing Qi, Erika D. von Gromoff, Fan Xu, Qian Zhao, Wei Yang, Dietmar Pfeifer, Wolfgang Maier, Lijiang Long, Ralf Baumeister   +8 more
openalex   +1 more source

The RasGAP-associated endoribonuclease G3BP assembles stress granules.

The Journal of cell biology, 2003
Stress granules (SGs) are formed in the cytoplasm in response to various toxic agents, and are believed to play a critical role in the regulation of mRNA metabolism during stress. In SGs, mRNAs are stored in an abortive translation initiation complex that can be routed to either translation initiation or degradation.
Tourrière, Hélène, Chebli, Karim, Zekri, Latifa, Courselaud, Brice, Blanchard, Jean Marie, Bertrand, Edouard, Tazi, Jamal   +6 more
openaire   +2 more sources