Results 71 to 80 of about 6,098 (159)
Purification, identification and characterization of mammalian endoribonucleases that degrade c-myc mRNA in vitro. [PDF]
, 2008 There is increasing evidence that mammalian endoribonucleases play a significant role in the degradation of messenger RNA (mRNA) and are key players in the regulation of gene expression particularly under conditions of cellular stress.
core +1 more source
Harnessing promoter elements to enhance gene editing in plants: perspectives and advances
Plant Biotechnology Journal, Volume 23, Issue 5, Page 1375-1395, May 2025.Summary Genome‐edited plants, endowed with climate‐smart traits, have been promoted as tools for strengthening resilience against climate change. Successful plant gene editing (GE) requires precise regulation of the GE machinery, a process controlled by the promoters, which drives its transcription through interactions with transcription factors (TFs ...
Nikita Gondalia +8 more
wiley +1 more source
A synthetic library of RNA control modules for predictable tuning of gene expression in yeast [PDF]
, 2011 Advances in synthetic biology have resulted in the development of genetic tools that support the design of complex biological systems encoding desired functions.
Babiskin, Andrew H. +1 more
core +4 more sources
Microbial Biotechnology, Volume 18, Issue 4, April 2025.All 32 diguanylate cyclase (DGC)‐encoding genes of P. aeruginosa PA14 were interrupted by premature STOP codons, introduced through a multiplexed cytosine base‐editor. The synthesis of c‐di‐GMP was impaired in the resulting strain lacking all 32 DGCs (strain PA14Δ32). Phenotypic analysis confirmed major behaviour changes in P. aeruginosa PA14Δ32, which
Román A. Martino +5 more
wiley +1 more source
Structure and Function of PRRSV nsp11 Endoribonuclease
DEStech Transactions on Biology and Health, 2018 Endoribonuclease (NendoU) is conserved and plays essential roles in viral life cycle among all nidoviruses. Porcine reproductive and respiratory syndrome virus (PRRSV) nonstructural protein 11 (nsp11) is shown to have NendoU activity and its multifunctions have been demonstrated, such as processing RNA, suppressing innate immunity system of infected ...
Zhong-Zhou Chen, Wei Wu, Manfeng Zhang
openaire +3 more sources
Plant RNases T2, but not Dicer-like proteins, are major players of tRNA-derived fragments biogenesis [PDF]
, 2019 RNA fragments deriving from tRNAs (tRFs) exist in all branches of life and the repertoire of their biological functions regularly increases. Paradoxically, their biogenesis remains unclear.
Cognat, V +8 more
core +2 more sources
Identification, characterization and classification of prokaryotic nucleoid‐associated proteins
Molecular Microbiology, Volume 123, Issue 3, Page 206-217, March 2025.Nucleoid‐associated proteins (NAPs) structure DNA by either bending, wrapping, bridging, or forming protein filaments on the DNA. We review newly identified NAPs and provide a list of simple biochemical assays to study the DNA‐structuring properties of novel NAPs. Abstract Common throughout life is the need to compact and organize the genome.
Samuel Schwab, Remus T. Dame
wiley +1 more source
When Ribonucleases Come into Play in Pathogens: A Survey of Gram-Positive Bacteria [PDF]
, 2012 It is widely acknowledged that RNA stability plays critical roles in bacterial adaptation and survival in different environments like those encountered when bacteria infect a host.
Jester, Brian C. +2 more
core +3 more sources
Genetic engineering in diatoms: advances and prospects
The Plant Journal, Volume 121, Issue 6, March 2025.SUMMARY Diatoms are among the most diverse and ecologically significant groups of photosynthetic microalgae, contributing over 20% of global primary productivity. Their ecological significance, unique biology, and genetic tractability make them ideal targets for genetic and genomic engineering and metabolic reprogramming.
Yixuan Li +4 more
wiley +1 more source
Phylogenetic Analysis of the Endoribonuclease Dicer Family
PLoS ONE, 2014 Dicers are proteins of the ribonuclease III family with the ability to process dsRNA, involved in regulation of gene expression at the post-transcriptional level. Dicers are conserved from basal metazoans to higher metazoans and contain a number of functional domains that interact with dsRNA.
Zeqian Gao +4 more
openaire +6 more sources