Results 71 to 80 of about 9,566 (262)

Quorum Sensing Extracellular Death Peptides Enhance the Endoribonucleolytic Activities of Mycobacterium tuberculosis MazF Toxins

mBio, 2018
mazEF is a toxin-antitoxin module located on chromosomes of most bacteria. MazF toxins are endoribonucleases antagonized by MazE antitoxins. Previously, we characterized several quorum sensing peptides called "extracellular death factors" (EDFs).
Akanksha Nigam, Sathish Kumar, Hanna Engelberg-Kulka   +2 more
doaj   +1 more source

Coupling immunity and programmed cell suicide in prokaryotes: Life-or-death choices [PDF]

, 2017
Host-pathogen arms race is a universal, central aspect of the evolution of life. Most organisms evolved several distinct yet interacting strategies of anti-pathogen defense including resistance to parasite invasion, innate and adaptive immunity, and ...
Abudayyeh, Amitai, Anantharaman, Asakura, Bach, Beloglazova, Bitton, Blanga-Kanfi, Briner, Daume, Davidov, Dixit, Dominguez, Doudna, Elmore, Forterre, Forterre, Fukuyo, Furuta, Gerdes, Gunderson, Hayes, He, He, Hooton, Hsu, Ichige, Iranzo, Iranzo, Ishikawa, Ishikawa, Jiang, Ka, Kaufmann, Kint, Klaiman, Klaiman, Kobayashi, Koonin, Koonin, Koonin, Koonin, Koonin, Koonin, Koonin, Koonin, Koonin, Kronenberg, Krutkina, Kumar, Leenay, Leplae, Levy, Lewis, Lewis, Loenen, Makarova, Makarova, Makarova, Makarova, Makarova, Makarova, Makarova, Mali, Marraffini, Marraffini, Meineke, Mohanraju, Mruk, Naito, Nam, Netea, Nunez, Nunez, Ohno, Penner, Pingoud, Rimer, Roberts, Sander, Shannon, Shmakov, Shmakov, Smith, Sorek, Stern, Szathmary, Upton, Uzan, van der Oost, Van Melderen, Vasu, Wei, Westra, Williams   +94 more
core   +1 more source

RNA elements and their biotechnological applications in plants

New Phytologist, EarlyView.
Summary Engineering of plants for improved traits and efficient heterologous protein production can be achieved by modifying or introducing cis‐ or trans‐acting RNA elements. The function of these elements depends not only on their nucleotide sequence but also on their highly dynamic higher order structures.
Filip Lastovka, Hadrien Peyret, George P. Lomonossoff, Betty Y.‐W. Chung   +3 more
wiley   +1 more source

Genetic Insight into the Domain Structure and Functions of Dicer-Type Ribonucleases

International Journal of Molecular Sciences, 2021
Ribonuclease Dicer belongs to the family of RNase III endoribonucleases, the enzymes that specifically hydrolyze phosphodiester bonds found in double-stranded regions of RNAs.
Kinga Ciechanowska, Maria Pokornowska, A. Kurzyńska-Kokorniak   +2 more
semanticscholar   +1 more source

Caenorhabditis elegans RIG-I Homolog Mediates Antiviral RNA Interference Downstream of Dicer-Dependent Biogenesis of Viral Small Interfering RNAs. [PDF]

, 2017
Dicer enzymes process virus-specific double-stranded RNA (dsRNA) into small interfering RNAs (siRNAs) to initiate specific antiviral defense by related RNA interference (RNAi) pathways in plants, insects, nematodes, and mammals.
Gina Broitman-Maduro, Hongshan Jiang, Jinfeng Lu, Jing Zhong, Morris Maduro, Rui Lu, Shou-wei Ding, Stephanie R. Coffman, W. Ian Lipkin, Wan-Xiang Li, Xunyang Guo   +10 more
core   +3 more sources

Conjugated polymer nanoparticles for effective siRNA delivery to tobacco BY-2 protoplasts

BMC Plant Biology, 2010
Background Post transcriptional gene silencing (PTGS) is a mechanism harnessed by plant biologists to knock down gene expression. siRNAs contribute to PTGS that are synthesized from mRNAs or viral RNAs and function to guide cellular endoribonucleases to ...
Verchot Jeanmarie, Ye Changming, Nguyen Alien, Silva Asitha T, Moon Joong   +4 more
doaj   +1 more source

Angiosperms Are Unique among Land Plant Lineages in the Occurrence of Key Genes in the RNA-Directed DNA Methylation (RdDM) Pathway [PDF]

, 2015
We are grateful for the FP7 Marie Curie IEF (Lu Ma), the FP7 Marie Curie ITN INTERCROSSING (Andrea Hatlen), the Czech Science Foundation (501/12/G090, Ales Kovarik), China Scholarship Council (Wencai Wang), and NERC (NE/ G01724/1, Laura Kelly, Ilia ...
Becher, H, Hatlen, A, Kelly, LJ, Kovarik, A, Leitch, AR, Leitch, IJ, Ma, L, Wang, W   +7 more
core   +2 more sources

Microbial diversity and function in the rhizosphere microbiome: Driving forces and monitoring approaches

Agrosystems, Geosciences &Environment, Volume 8, Issue 3, September 2025.
Abstract As an ecological unit, the rhizosphere microbiome preserves an enormous and largely unexplored diversity of microbes that play essential roles in plant health and soil functions. Omics technologies encompassing high‐throughput approaches such as metagenomics, metatranscriptomics, and metaproteomics provide helpful tools to unravel the ...
Chinenyenwa Fortune Chukwuneme, Olubukola Oluranti Babalola   +1 more
wiley   +1 more source

The Lepidopteran endoribonuclease-U domain protein P102 displays dramatically reduced enzymatic activity and forms functional amyloids [PDF]

, 2014
Hemocytes of Heliothis virescens (F.) (Lepidoptera, Noctuidae) larvae produce a protein, P102, with a putative endoribonuclease-U domain. In previous works we have shown that P102 is involved in Lepidopteran immune response by forming amyloid fibrils ...
Falabella, P., Grimaldi, A., Laurino, S., Monn\ue9, M., Pascale, M., Riviello, L., Tettamanti, G., Vogel, H.   +7 more
core   +1 more source

ATF6 Alleviates Endothelial Inflammation Following Extended Hepatectomy Through Inhibition of TRIM10/NF‐κB Signaling

The FASEB Journal, Volume 39, Issue 16, 31 August 2025.
Activating transcription factor 6 (ATF6) in liver endothelial cells is upregulated and activated following the extended hepatectomy in both humans and rodents. ATF6 deficiency or pharmacological inhibition of ATF6 leads to severe endothelial inflammation in mice and HUVECs.
Cheng‐Cheng Shi, Dong‐Jing Yang, Yang Bai, Binhui Zhou, Yao‐Hui Sun, Xiao‐Ran Xu, Wen‐Zhi Guo, Shui‐Jun Zhang, Yinming Liang, Yang Jin, Ji‐Hua Shi   +10 more
wiley   +1 more source