Results 81 to 90 of about 9,566 (262)
Salicylic acid collaborates with gene silencing to tomato defense against tomato yellow leaf curl virus (TYLCV) [PDF]
, 2018 Antiviral research in plants has been focused on RNA silencing (i.e. RNA interference), and several studies suggest that salicylic acid (SA)-mediated resistance is a key part of plant antiviral defense.
Crabbe, M. James C. +5 more
core
Dormant non-culturable Mycobacterium tuberculosis retains stable low-abundant mRNA [PDF]
, 2015 BACKGROUND: Dormant Mycobacterium tuberculosis bacilli are believed to play an important role in latent tuberculosis infection. Previously, we have demonstrated that cultivation of M.
Azhikina, Tatyana L. +5 more
core +1 more source
RNA Recognition and Cleavage by the SARS Coronavirus Endoribonuclease
Journal of Molecular Biology, 2006 The emerging disease SARS is caused by a novel coronavirus that encodes several unusual RNA-processing enzymes, including non-structural protein 15 (Nsp15), a hexameric endoribonuclease that preferentially cleaves at uridine residues. How Nsp15 recognizes and cleaves RNA is not well understood and is the subject of this study.
Jingchuan Sun +4 more
openaire +3 more sources
The endoribonuclease YbeY is linked to proper cellular morphology and virulence in 2 Brucella abortus [PDF]
, 2018 The endoribonuclease YbeY is one of the most well conserved proteins across the kingdoms of life. In the present study, we demonstrate that YbeY in Brucella abortus is linked to a variety of important activities, including proper cellular morphology ...
Budnick, James A. +5 more
core +1 more source
Angewandte Chemie International Edition, Volume 64, Issue 27, July 1, 2025.The highly negatively charged phosphodiester groups of nucleic acids and cyclic (di‐)nucleotides often interact with amino acids containing polar or positively charged sidechains. Due to charge repulsion with their negatively charged carboxylate groups in their side chains, glutamate and aspartate are considered to be detrimental to such interactions ...
Konstantin Neißner +5 more
wiley +1 more source
mBio, 2017 Ribonucleases facilitate rapid turnover of RNA, providing cells with another mechanism to adjust transcript and protein levels in response to environmental conditions. While many examples have been documented, a comprehensive list of RNase targets is not
Gina C. Gordon +2 more
doaj +1 more source
In vitro reconstitution of Cascade-mediated CRISPR immunity in Streptococcus thermophilus [PDF]
, 2013 Clustered regularly interspaced short palindromic repeats (CRISPR)-encoded immunity in Type I systems relies on the Cascade (CRISPR-associated complex for antiviral defence) ribonucleoprotein complex, which triggers foreign DNA degradation by an ...
Giedrius Gasiunas +8 more
core +2 more sources
FASEB BioAdvances, Volume 7, Issue 7, July 2025.Endoplasmic Reticulum (ER) Stress‐Unfolded Protein Response (UPR) sensor ERN1 regulates organic dust induction of lung inflammation. Treatment of bronchial epithelial cells and mouse lungs with organic dust extract increased ERN1 expression and activation.
Shilpa Kusampudi +2 more
wiley +1 more source
The sequences and activities of RegB endoribonucleases of T4-related bacteriophages.
Nucleic Acids Research, 2004 The RegB endoribonuclease encoded by bacteriophage T4 is a unique sequence-specific nuclease that cleaves in the middle of GGAG or, in a few cases, GGAU tetranucleotides, preferentially those found in the Shine-Dalgarno regions of early phage mRNAs.
Lina Piešinienė +3 more
semanticscholar +1 more source
Translational regulation in mycobacteria and its implications for pathogenicity. [PDF]
, 2018 Protein synthesis is a fundamental requirement of all cells for survival and replication. To date, vast numbers of genetic and biochemical studies have been performed to address the mechanisms of translation and its regulation in Escherichia coli, but ...
Cortes, Teresa +2 more
core +1 more source