Results 151 to 160 of about 187,332 (400)
Regulation of NKG2D-Dependent NK Cell Functions: The Yin and the Yang of Receptor Endocytosis. [PDF]
, 2017 Natural-killer receptor group 2, member D (NKG2D) is a well characterized natural killer (NK) cell activating receptor that recognizes several ligands poorly expressed on healthy cells but up-regulated upon stressing stimuli in the context of cancer or ...
Molfetta, R +3 more
core +2 more sources
Endoplasmic reticulum–endosome contact increases as endosomes traffic and mature
Molecular Biology of the Cell, 2013 Endosomes do not traffic autonomously but instead associate with the ER membrane. ER tubules wrap around and maintain contact with both early and late endosomes by ER ring rearrangements.
J. Friedman +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong +6 more
wiley +1 more source
TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes
Journal of Cell Biology, 2012 The noncatalytic RabGAP protein TBC1D14 regulates the Rab11- and ULK1-positive recycling endosomes required for autophagosome formation upon ...
A. Longatti +5 more
semanticscholar +1 more source
Advanced Science, EarlyView.Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu +11 more
wiley +1 more source
New aspects of a small GTPase RAB35 in brain development and function
Neural Regeneration ResearchIn eukaryotic cells, organelles in the secretory, lysosomal, and endocytic pathways actively exchange biological materials with each other through intracellular membrane trafficking, which is the process of transporting the cargo of proteins, lipids, and
Ikuko Maejima, Ken Sato
doaj +1 more source
The Arabidopsis Intracellular Na+/H+ Antiporters NHX5 and NHX6 Are Endosome Associated and Necessary for Plant Growth and Development [PDF]
, 2011 Elias Bassil +9 more
openalex +1 more source
TORC1 Determines Fab1 Lipid Kinase Function at Signaling Endosomes and Vacuoles [PDF]
, 2020 Zilei Chen +13 more
openalex +1 more source
The recycling endosome protein Rab25 coordinates collective cell movements in the zebrafish surface epithelium [PDF]
, 2021 Patrick Morley Willoughby +10 more
openalex +1 more source
Advanced Science, EarlyView.We designed a synthetic DNA origami needle‐like structure inspired by bacteriophages for targeted drug delivery. Functionalized with trastuzumab antibodies, cholesterol, and dyes, it selectively targets SKBR3 cancer cells. A glutathione‐triggered dye payload enables controlled release, and delivery is verified using confocal microscopy and live cell ...
Anirban Samanta +7 more
wiley +1 more source