Results 271 to 280 of about 185,575 (398)

Unpacking the Tumor Protein D52-like Family: Roles in Intracellular Trafficking and Cancer Progression. [PDF]

Cells
Dorward EL, Ortiz M, Weekley CM, Myo Min KK, Duijf PHG, Barreto SG, Parker MW, Bonder CS.   +7 more
europepmc   +1 more source

Characterizing KIF16B in Neurons Reveals a Novel Intramolecular “Stalk Inhibition” Mechanism That Regulates Its Capacity to Potentiate the Selective Somatodendritic Localization of Early Endosomes [PDF]

, 2015
Atena Farkhondeh, Shinsuke Niwa, Yosuke Takei, Nobutaka Hirokawa   +3 more
openalex   +1 more source

LRRK2 as a Potential Disease‐Modifying Target in Sporadic Parkinson's Disease

Movement Disorders, EarlyView.
Abstract A growing understanding of the role that leucine‐rich repeat kinase 2 (LRRK2) plays in Parkinson's disease (PD) supports continued focus on this enzyme as a therapeutic target for PD. Accumulating evidence suggests that there are phenotypic, neuropathologic, and biological similarities between sporadic PD (sPD) and familial forms in which ...
Anthony E. Lang, Robert A. Hauser, Lorraine V. Kalia, Bonnie Hersh, Zdenek Berger, Roy Llorens Arenas, Coro Paisan‐Ruiz, Kyle Fraser, Danna Jennings, Jillian H. Kluss, Sarah Huntwork‐Rodriguez, Anastasia G. Henry, J. Timothy Greenamyre   +12 more
wiley   +1 more source

Intracellular Transport of PD-L1 by Rab10-Positive Tubular Endosomes Originated from Macropinocytic Cups in RAW264 Macrophage-Like Cells. [PDF]

Acta Histochem Cytochem
Kawai K, Ishikawa Y, Egami Y, Araki N.
europepmc   +1 more source

pH-responsive bond as a linker for the release of chemical drugs from RNA–drug complexes in endosome or lysosome [PDF]

Piotr Rychahou, Sijin Guo, Yinan Zhang, Nicole Rychagov, Yekaterina Y. Zaytseva, Heidi L. Weiss, B. Mark Evers, Peixuan Guo   +7 more
openalex   +1 more source

Parkinson's‐Linked LRRK2 and GBA1 Mutations Modulate the Peripheral Immune Response to Pseudomonas aeruginosa

Movement Disorders, EarlyView.
Abstract Background Peripheral disease mechanisms such as immune dysregulation may contribute to Parkinson's disease (PD). To investigate interactions between common PD mutations and immune responses to environmental pathogens, we studied responses to Pseudomonas aeruginosa (P.
Julian R. Mark, Hannah A. Staley, Ann M. Titus, Julian Agin‐Liebes, Alicia Garrido, Laura Hughes, Nicolas Dzamko, Rebecca L. Wallings, Malú Gámez Tansey   +8 more
wiley   +1 more source

Deacidification of the Endolysosomal System by the Vesicular Proton Pump V-ATPase Inhibitor Bafilomycin A1 Affects EGF Receptor Endocytosis Differently in Endometrial MSC and HeLa Cells. [PDF]

Int J Mol Sci
Salova AV, Belyaeva TN, Litvinov IK, Kharchenko MV, Kornilova ES.   +4 more
europepmc   +1 more source

A Selective Transport Route from Golgi to Late Endosomes That Requires the Yeast Gga Proteins [PDF]

, 2000
Michael W. Black, Hugh R.B. Pelham
openalex   +1 more source

Earliest endosomes [PDF]

Nature Reviews Molecular Cell Biology, 2009
openaire   +1 more source

VPS13A Deficiency Leads to Impaired Lipid Distribution and Alteration of Mitochondrial Calcium Homeostasis in Fibroblasts of VPS13A Disease Patients

Movement Disorders, EarlyView.
Abstract Background Membrane contact sites are crucial for the exchange of ions or lipids and thus are critical for the function and maintenance of organelles. VPS13A is a membrane‐residing, bridge‐like protein connecting two membranes to enable bulk lipid transfer. Loss‐of‐function mutations in the VPS13A gene cause VPS13A disease.
Dajana Grossmann, Adrian Spranger, Emily Fischer, Johanna W. Schubarth, Jenny Leopold, Hannes Glaß, Sebastian Klicker, My Uyen Dang Thi, Anna Elisabeth Bartalis, Andreas Hermann, Kevin Peikert   +10 more
wiley   +1 more source