Results 301 to 310 of about 185,575 (398)

TPC Proteins Are Phosphoinositide- Activated Sodium-Selective Ion Channels in Endosomes and Lysosomes

Cell, 2012
Xiang Wang, Xiaoli Zhang, Xian-Ping Dong, M. Samie, Xinran Li, Xi-ping Cheng, Andrew Goschka, Dongbiao Shen, Yandong Zhou, J. Harlow, M. Zhu, D. Clapham, Dejian Ren, Haoxing Xu   +13 more
semanticscholar   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Endosome-phagophore linking assemblies for the degradation of membrane/extracellular proteins. [PDF]

Nat Commun
Wang P, Sun H, An P, Tang P, Liu Q, Tang Z, Lv T, Ruan J, Zhen X, Han L.   +9 more
europepmc   +1 more source

[15] Transport from late endosomes to trans-golgi network in semiintact cell extracts

, 1992
Yukiko Goda, Thierry Soldati, Suzanne R. Pfeffer   +2 more
openalex   +2 more sources

Bioengineered Bacterial Vesicles and Biomimetic Hybrids Eliminate Biofilms and Balance the Gut Microbiome

Small, EarlyView.
Biomimetic nanocarriers based on liposomes and Myxobacteria outer‐membrane vesicles (OMVs) are effective antibiotic delivery systems. Hybrids have a higher drug loading and can target intracellular pathogens, while OMVs evade immune clearance. Biomimetic nanoantibiotics effectively eliminate the biofilms of Gram‐negative bacteria. Besides, Myxobacteria
Leila Pourtalebi Jahromi, Benedikt Kronast, Jennifer Munkert, Lorenzo Sana, Marcus Koch, Heike Danzer, Sirka Dormeyer, Shuhan Jiang, Fabian Herrmann, Matthias Weiler, Anna Kashkanova, Vahid Sandoghdar, Mario M. Zaiss, Gregor Fuhrmann   +13 more
wiley   +1 more source

LAMP2A regulates endosomal protein composition and membrane identity in exosome biogenesis. [PDF]

iScience
Ferreira JV, Ferraz LC, da Rosa Soares A, Ejtehadifar M, Carvalho AS, Hall MJ, Morello J, Beck HC, Ramalho JS, Matthiesen R, Pereira P.   +10 more
europepmc   +1 more source

Decoding pH‐Driven Phase Transition of Lipid Nanoparticles

Small, EarlyView.
Ionizable aminolipids govern lipid nanoparticle (LNP) function through environment‐dependent protonation. Constant‐pH molecular dynamics reveal intrinsic, apparent, and surface pKa${\rm pK}_{\text{a}}$ values within LNP‐mimetic membranes, demonstrating that the LNP lipid environment induces a pronounced downward pKa${\rm pK}_{\text{a}}$ shift exceeding
Marius F.W. Trollmann, Rainer A. Böckmann   +1 more
wiley   +1 more source

NoxO1 promotes endosome formation and reduces intracellular vesicle processing. [PDF]

Redox Biol
Hebchen M, Herwig F, Schader T, Spaeth M, Müller N, Schröder K.   +5 more
europepmc   +1 more source

Endosome signaling

The Journal of Cell Biology, 2006
openaire   +2 more sources

Medical Gas Plasma Inactivates Adenoviruses via Capsid Oxidation

Small, EarlyView.
Oxidative modification of three adenoviral capsid proteins after gas plasma treatment. Schematic representation of the viral infection process, starting with the initial attachment of the virus via its fiber protein binding to the cellular receptors (CAR and/or CD46). In the secondary attachment step, the penton base binds to integrin structures on the
Anke Schmidt, Meike Heuser, Paul Schulan, Lea Miebach, Alice Martinet, Marcus Frank, Kristian Wende, Sander Bekeschus   +7 more
wiley   +1 more source