Results 321 to 330 of about 185,575 (398)

YTHDF2 regulates self non-coding RNA metabolism to control inflammation and tumorigenesis. [PDF]

Nat Commun
Yang S, Cui YH, Li H, Wei J, Park G, Sun M, Verghese M, Wilkinson E, Nam T, Lungstrom LL, Cui X, Ryu TY, Chen J, Bissonnette M, He C, He YY.   +15 more
europepmc   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

A luminescent reporter assay to quantify SORL1 ectodomain shedding and retromer-dependent endosome recycling activity. [PDF]

J Biol Chem
Fazeli E, Jan A, Huber AK, Jensen AMG, Fazeli E, Klein J, Merchant K, Andersen OM.   +7 more
europepmc   +1 more source

Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice

British Journal of Pharmacology, EarlyView.
Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro, Pietro Pola, Michela Argentieri, Alessia Frezza, Matilde Marini, Francesco De Logu, Valentina Albanese, Marie Soukupova, Davide Malfacini, Nurulain T. Zaveri, Romina Nassini, Dane D. Jensen, Pierangelo Geppetti, Girolamo Calò, Chiara Ruzza   +14 more
wiley   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

Experience-dependent reconfiguration of thermoreceptors regulates neuronal response plasticity. [PDF]

Curr Biol
Harris N, Dutta P, Krishnan N, Nurrish S, Wilder EC, Sengupta P.   +5 more
europepmc   +1 more source

Rab14 limits the sorting of Glut4 from endosomes into insulin-sensitive regulated secretory compartments in adipocytes

, 2016
Paul Duffield Brewer, Estifanos N. Habtemichael, Irina Romenskaia, Adelle C.F. Coster, Cynthia Corley Mastick   +4 more
openalex   +2 more sources

Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu, Xingju Zou, Yang Zheng, Chen Sun, Cheng Peng   +4 more
wiley   +1 more source

Insights into lysosome-related organelle biogenesis: melanosome as a model organelle. [PDF]

Front Cell Dev Biol
Barral DC, Delevoye C, Larue L, Seabra MC, Raposo G, Setty SRG.   +5 more
europepmc   +1 more source

eLife assessment: Visualization of endogenous G proteins on endosomes and other organelles

Felix Campelo
openalex   +1 more source