Results 51 to 60 of about 7,550 (174)
Blood Pressure, 2018 Background: Endostatin, cleaved from collagen XVIII in the extracellular matrix, is a promising circulating biomarker for cardiovascular damage. It possesses anti-angiogenic and anti-fibrotic functions and has even been suggested to be involved in blood ...
Jonas Wuopio +8 more
doaj +1 more source
Journal of the Egyptian National Cancer Institute, 2015 Background: A disintegrin and metalloprotease 8 (ADAM8) is a trans-membrane protein, which is involved in cell adhesion, signaling and migration as well as the proteolytic cleavage of various substrates.
Dalia M. Abd El-Rehim +1 more
doaj +1 more source
Frontiers in Oncology, 2021 IntroductionA modified and recombinant human endostatin (Rh-endostatin) is often used in the control of malignant pleural effusion (MPE) through intrapleural infusion.ObjectivesTo demonstrate the clinical response, survival, and safety of Rh-endostatin ...
Cheng-Qiong Wang +18 more
doaj +1 more source
MedComm, Volume 7, Issue 9, September 2026.Mitochondria is the hub of apoptosis in various diseases. The disruption of mitochondrial structure (including membrane rupture, cristae remodeling, and mitochondrial membrane lipid redistribution), the imbalance of mitochondrial dynamics (including fusion and fission, autophagy), the release, disruption, and mutation of mitochondria DNA, as well as ...
Rubin Tan +9 more
wiley +1 more source
Endostatin and anastellin inhibit distinct aspects of the angiogenic process
Journal of Experimental & Clinical Cancer Research, 2008 Background Endostatin and anastellin, fragments of collagen type XVIII and fibronectin, respectively, belong to a family of endogenous inhibitors of angiogenesis which inhibit tumor growth and metastasis in a number of mouse models of human cancer.
Pumiglia Kevin M +3 more
doaj +1 more source
Natural Biomaterials for Osteochondral Repair: From Source to Strategy
Advanced Healthcare Materials, Volume 15, Issue 27, 17 July 2026.Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu +5 more
wiley +1 more source
Can endocan serve as a molecular “hepatostat” in liver regeneration?
Molecular Medicine, 2023 Background Intriguingly, liver regeneration after injury does not induce uncontrolled growth and the underlying mechanisms of such a “hepatostat” are still not clear. Endocan, a proteoglycan, was implicated in liver regeneration.
Sinan Efe Yazici +5 more
doaj +1 more source
Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape
The FEBS Journal, Volume 293, Issue 13, Page 3991-4013, July 2026.The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto +9 more
wiley +1 more source
Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma
The FEBS Journal, Volume 293, Issue 13, Page 4043-4063, July 2026.Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris +2 more
wiley +1 more source
Insights into differential endostatin activity
Cancer Biology & Therapy, 2004 commentary to Opposite Effects of Endostatin on Different Endothelial Cells Annette Schmidt, Klaus Addicks and Wilhelm ...
Timothy K, Maclachlan +1 more
openaire +2 more sources