Results 41 to 50 of about 1,684,780 (315)

Anti-inflammatory compounds reduce equine herpesvirus type 1 replication and cell-to-cell spread

open access: yesFrontiers in Veterinary Science, 2023
Equine herpesvirus type 1 (EHV-1) is a highly transmissible pathogen that leads to a variety of clinical disease outcomes in infected horses. A major sequela that can occur after an EHV-1 infection is a neurological disease termed equine herpesvirus ...
Jeanette B. Black, Arthur R. Frampton
doaj   +1 more source

Endothelial Dysfunction, Inflammation and Coronary Artery Disease: Potential Biomarkers and Promising Therapeutical Approaches

open access: yesInternational Journal of Molecular Sciences, 2021
Coronary artery disease (CAD) and its complications are the leading cause of death worldwide. Inflammatory activation and dysfunction of the endothelium are key events in the development and pathophysiology of atherosclerosis and are associated with an ...
D. Medina-Leyte   +5 more
semanticscholar   +1 more source

Scavenger Receptors and Their Potential as Therapeutic Targets in the Treatment of Cardiovascular Disease

open access: yesInternational Journal of Hypertension, 2010
Scavenger receptors act as membrane-bound and soluble proteins that bind to macromolecular complexes and pathogens. This diverse supergroup of proteins mediates binding to modified lipoprotein particles which regulate the initiation and progression of ...
Sam L. Stephen   +7 more
doaj   +1 more source

Scavenger Receptor Structure and Function in Health and Disease

open access: yesCells, 2015
Scavenger receptors (SRs) are a ‘superfamily’ of membrane-bound receptors that were initially thought to bind and internalize modified low-density lipoprotein (LDL), though it is currently known to bind to a variety of ligands including endogenous ...
Izma Abdul Zani   +6 more
doaj   +1 more source

Circulating Endothelial Cells, Endothelial Progenitor Cells, and Endothelial Microparticles in Cancer

open access: yesNeoplasia, 2006
Cancer, a proliferative disease hallmarked by abnormal cell growth and spread, is largely dependent on tumor neoangiogenesis, with evidence of vascular endothelial dysfunction. Novel ways to assess vascular function in cancer include measuring levels of circulating endothelial cells (CEC).
P.K.Y. Goon   +4 more
openaire   +3 more sources

Effects of circuit exercise training on vascular health and blood pressure

open access: yesPreventive Medicine Reports, 2018
As the global burden of cardiovascular disease (CVD) rises, public health-related interventions aimed at prevention of heart disease have gained medical attention.
Allyson K. Getty   +8 more
doaj   +1 more source

Inflammatory Mechanisms Contributing to Endothelial Dysfunction

open access: yesBiomedicines, 2021
Maintenance of endothelial cell integrity is an important component of human health and disease since the endothelium can perform various functions including regulation of vascular tone, control of hemostasis and thrombosis, cellular adhesion, smooth ...
P. Theofilis   +6 more
semanticscholar   +1 more source

Influence of Shear Stress, Inflammation and BRD4 Inhibition on Human Endothelial Cells: A Holistic Proteomic Approach

open access: yesCells, 2022
Atherosclerosis is an important risk factor in the development of cardiovascular diseases. In addition to increased plasma lipid concentrations, irregular/oscillatory shear stress and inflammatory processes trigger atherosclerosis.
Johannes Jarausch   +7 more
doaj   +1 more source

Glycosylation in the Tumor Microenvironment: Implications for Tumor Angiogenesis and Metastasis

open access: yesCells, 2019
Just as oncogene activation and tumor suppressor loss are hallmarks of tumor development, emerging evidence indicates that tumor microenvironment-mediated changes in glycosylation play a crucial functional role in tumor progression and metastasis ...
Kevin Brown Chandler   +2 more
doaj   +1 more source

Nuclear Mechanosensation and Mechanotransduction in Vascular Cells

open access: yesFrontiers in Cell and Developmental Biology, 2022
Vascular cells are constantly subjected to physical forces associated with the rhythmic activities of the heart, which combined with the individual geometry of vessels further imposes oscillatory, turbulent, or laminar shear stresses on vascular cells ...
Jocelynda Salvador   +1 more
doaj   +1 more source

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