Results 21 to 30 of about 1,684,780 (315)

Endothelial dysfunction in COVID-19: an overview of evidence, biomarkers, mechanisms and potential therapies

open access: yesActa Pharmacologica Sinica, 2022
The fight against coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is still raging. However, the pathophysiology of acute and post-acute manifestations of COVID-19 (long COVID-19) is understudied.
Suo Xu, I. Ilyas, Jianping Weng
semanticscholar   +1 more source

Ubiquitination of basal VEGFR2 regulates signal transduction and endothelial function

open access: yesBiology Open, 2017
Cell surface receptors can undergo recycling or proteolysis but the cellular decision-making events that sort between these pathways remain poorly defined.
Gina A. Smith   +6 more
doaj   +1 more source

Endothelial Dysfunction in Hypertension: Current Concepts and Clinical Implications

open access: yesFrontiers in Medicine, 2022
Endothelium plays a fundamental role in the cardiovascular system, forming an interface between blood and adjacent tissues by regulating the vascular tone through the synthesis of nitric oxide, prostaglandins and other relaxing factors.
G. Gallo, M. Volpe, C. Savoia
semanticscholar   +1 more source

Vascular Health in American Football Players: Cardiovascular Risk Increased in Division III Players

open access: yesInternational Journal of Vascular Medicine, 2016
Studies report that football players have high blood pressure (BP) and increased cardiovascular risk. There are over 70,000 NCAA football players and 450 Division III schools sponsor football programs, yet limited research exists on vascular health of ...
Deborah L. Feairheller   +17 more
doaj   +1 more source

Delivery of Therapeutic miRNA via Plasma-Polymerised Nanoparticles Rescues Diabetes-Impaired Endothelial Function

open access: yesNanomaterials, 2023
MicroRNAs (miRNAs) are increasingly recognised as key regulators of the development and progression of many diseases due to their ability to modulate gene expression post-translationally.
Yuen Ting Lam   +7 more
doaj   +1 more source

The LOX-1 Scavenger Receptor and Its Implications in the Treatment of Vascular Disease

open access: yesCardiology Research and Practice, 2012
Cardiovascular disease is the leading cause of death. The disease is due to atherosclerosis which is characterized by lipid and fat accumulation in arterial blood vessel walls. A key causative event is the accumulation of oxidised low density lipoprotein
M. W Twigg   +3 more
doaj   +1 more source

miR-150-PTPMT1-cardiolipin signaling in pulmonary arterial hypertension

open access: yesMolecular Therapy: Nucleic Acids, 2021
Circulating levels of endothelial miR-150 are reduced in pulmonary arterial hypertension (PAH) and act as an independent predictor of patient survival, but links between endothelial miR-150 and vascular dysfunction are not well understood. We studied the
Giusy Russomanno   +9 more
doaj   +1 more source

Vascular endothelial cell development and diversity

open access: yesNature Reviews Cardiology, 2022
Advances in single-cell RNA sequencing technologies in the past 5 years have led to a greater understanding of endothelial cell development and heterogeneity.
E. Trimm, Kristy Red-Horse
semanticscholar   +1 more source

Masson’s Tumour: Two Case Reports with a Brief Review of Literature [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2019
Masson’s tumour, also known as Intravascular Papillary Endothelial Hyperplasia (IPEH) is an uncommon vascular lesion. Although benign, the lesion can mimic malignant tumours like angiosarcomas.
Neelam Sood, Navmeet Soin
doaj   +1 more source

Blood-Brain Barrier Dysfunction in CNS Disorders and Putative Therapeutic Targets: An Overview

open access: yesPharmaceutics, 2021
The blood-brain barrier (BBB) is a fundamental component of the central nervous system (CNS). Its functional and structural integrity is vital to maintain the homeostasis of the brain microenvironment by controlling the passage of substances and ...
Sabrina Rahman Archie   +2 more
doaj   +1 more source

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