Results 41 to 50 of about 931,139 (309)

Estrogen, angiogenesis, immunity and cell metabolism: Solving the puzzle [PDF]

, 2018
Estrogen plays an important role in the regulation of cardiovascular physiology and the immune system by inducing direct effects on multiple cell types including immune and vascular cells. Sex steroid hormones are implicated in cardiovascular protection,
Bolego, Chiara, BOSCARO, CARLOTTA, Cignarella, Andrea, Tedesco, Serena, Trenti, Annalisa, Trevisi, Lucia   +5 more
core   +5 more sources

Increased expression of cell adhesion molecules in myofasciitis

Frontiers in Neurology, 2023
BackgroundMyofasciitis is a heterogeneous group of diseases pathologically characterized by inflammatory cell infiltration into the fascia. Endothelial activation plays a critical role in the pathogenesis of the inflammatory response.
Xue Ma, Xue Ma, Huajie Gao, Li Xu, Zhuajin Bi, Suqiong Ji, Bitao Bu   +6 more
doaj   +1 more source

Clinical expression of plakophilin-2 mutations in familial arrhythmogenic right ventricular cardiomyopathy [PDF]

, 2006
Background - Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited cardiac disorder characterized by loss of cardiomyocytes and their replacement by adipose and fibrous tissue.
Asimaki, A, Ebrahim, HY, Elliott, PM, Evans, A, Hitomi, N, McKenna, WJ, Norman, M, Pantazis, A, Sen-Chowdhry, S, Shaw, AL, Syrris, P, Ward, D   +11 more
core   +1 more source

Combined LXR and RXR Agonist Therapy Increases ABCA1 Protein Expression and Enhances ApoAI-Mediated Cholesterol Efflux in Cultured Endothelial Cells

Metabolites, 2021
Endothelial ABCA1 expression protects against atherosclerosis and this atheroprotective effect is partially attributed to enhancing apoAI-mediated cholesterol efflux.
Kun Huang, Hanjoong Jo, Jing Echesabal-Chen, Alexis Stamatikos   +3 more
doaj   +1 more source

Exercise-Derived Microvesicles: A Review of the Literature [PDF]

, 2018
Initially suggested as simple cell debris, cell-derived microvesicles (MVs) have now gained acceptance as recognized players in cellular communication and physiology.
Mourot, Laurent, Rakobowchuk, Mark, Wilhelm, Eurico N.   +2 more
core   +2 more sources

Monocyte-Induced Endothelial Calcium Signaling Mediates Early Xenogeneic Endothelial Activation [PDF]

American Journal of Transplantation, 2005
Hallmarks of delayed xenograft rejection include monocyte infiltration, endothelial cell activation and disruption of the endothelial barrier. The monocyte is an important initiator of this type of rejection because monocytes accumulate within hours after xenografting and prior monocyte depletion suppresses the development of this type of rejection ...
Mark D, Peterson, Ekaterina, Vlasova, Caterina, Di Ciano-Oliveira, Gregory P, Downey, Myron I, Cybulsky, Andras, Kapus, Thomas K, Waddell   +6 more
openaire   +2 more sources

The vascular endothelium as decision maker in lung injury

Frontiers in Cell and Developmental Biology
The vascular endothelium is the largest organ in the human body, capable of performing a wide range of cellular signaling and synthetic functions. It is also subjected to considerable mechanical stress due to the shear forces generated by blood flow ...
Diana Klein
doaj   +1 more source

Multimodal measurement of glycocalyx degradation during coronary artery bypass grafting

Frontiers in Medicine, 2022
BackgroundGlycocalyx shedding and subsequent endothelial dysfunction occur in many conditions, such as in sepsis, in critical illness, and during major surgery such as in coronary artery bypass grafting (CABG) where it has been shown to associate with ...
Martine E. Bol, Martine E. Bol, J. B. Huckriede, K. G. H. van de Pas, T. Delhaas, R. Lorusso, R. Lorusso, G. A. F. Nicolaes, J. E. M. Sels, J. E. M. Sels, J. E. M. Sels, M. C. G. van de Poll, M. C. G. van de Poll, M. C. G. van de Poll   +13 more
doaj   +1 more source

Connexin40 controls endothelial activation by dampening NFκB activation

Oncotarget, 2017
Connexins are proteins forming gap junction channels for intercellular communication. Connexin40 (Cx40) is highly expressed by endothelial cells (ECs) of healthy arteries but this expression is lost in ECs overlying atherosclerotic plaques. Low/oscillatory shear stress observed in bends and bifurcations of arteries is atherogenic partly through ...
Denis, Jean-François, Scheckenbach, Ludwig, Pfenniger, Anna, Meens, Merlijn, Krams, Rob, Miquerol, Lucile, Taffet, Steven, Chanson, Marc, Delmar, Mario, Kwak, Brenda   +9 more
openaire   +6 more sources

Polystyrene microplastic particles induce endothelial activation

PLOS ONE, 2021
Due to its increasing production, durability and multiple applications, plastic is a material we encounter every day. Small plastic particles from the μm to the mm range are classified as microplastics and produced for cosmetic and medical products, but are also a result of natural erosion and decomposition of macroplastics.
Ann-Kathrin Vlacil, Sebastian Bänfer, Ralf Jacob, Nicole Trippel, Istemi Kuzu, Bernhard Schieffer, Karsten Grote   +6 more
openaire   +5 more sources