Results 31 to 40 of about 931,139 (309)

Filamin-A is required for the incorporation of tissue factor into cell-derived microvesicles [PDF]

, 2013
We previously reported that the incorporation of tissue factor (TF) into cell-derived microvesicles (MVs) is regulated by the phosphorylation of the cytoplasmic domain of TF.
Collier, Mary E. W., Ettelaie, Camille, Maraveyas, Anthony   +2 more
core   +1 more source

Characterization of Plasma-Derived Small Extracellular Vesicles Indicates Ongoing Endothelial and Platelet Activation in Patients with Thrombotic Antiphospholipid Syndrome

Cells, 2020
Antiphospholipid syndrome (APS) is a systemic autoimmune disease, characterized by thrombosis, obstetric complications and the presence of antiphospholipid antibodies (aPL), which drive endothelial injury and thrombophilia.
Ula Štok, Elizabeta Blokar, Metka Lenassi, Marija Holcar, Mojca Frank-Bertoncelj, Andreja Erman, Nataša Resnik, Snežna Sodin-Šemrl, Saša Čučnik, Katja Perdan Pirkmajer, Aleš Ambrožič, Polona Žigon   +11 more
doaj   +1 more source

Reciprocal regulation of NRF2 by autophagy and ubiquitin–proteasome modulates vascular endothelial injury induced by copper oxide nanoparticles

Journal of Nanobiotechnology, 2022
Highlights 1. CuONPs exposure activates NRF2 signaling in vascular endothelial cells and mouse thoracic aorta. 2. KEAP1 is dispensable for NRF2 activation in CuONPs-treated vascular endothelial cells. 3.
Na Li, Hang Du, Lejiao Mao, Ge Xu, Mengling Zhang, Yinzhen Fan, Xiaomei Dong, Lijun Zheng, Bin Wang, Xia Qin, Xuejun Jiang, Chengzhi Chen, Zhen Zou, Jun Zhang   +13 more
doaj   +1 more source

Vascular Signaling in Allogenic Solid Organ Transplantation – The Role of Endothelial Cells

Frontiers in Physiology, 2020
Graft rejection remains the major obstacle after vascularized solid organ transplantation. Endothelial cells, which form the interface between the transplanted graft and the host’s immunity, are the first target for host immune cells.
Laura Kummer, Marcin Zaradzki, Vijith Vijayan, Rawa Arif, Markus A. Weigand, Stephan Immenschuh, Andreas H. Wagner, Jan Larmann   +7 more
doaj   +1 more source

A systematic review of diagnostic, prognostic, and risk blood and urine biomarkers of transplant-associated thrombotic microangiopathy

Frontiers in Immunology, 2023
Transplant-associated thrombotic microangiopathy (TA-TMA) is an increasingly recognized complication of allogeneic and autologous hematopoietic cellular therapy (HCT), associated with significant morbidity and mortality.
Michelle L. Schoettler, Michelle L. Schoettler, Harshil Bhatt, Sumithira Vasu   +3 more
doaj   +1 more source

Total parasite biomass but not peripheral parasitaemia is associated with endothelial and haematological perturbations in Plasmodium vivax patients

eLife, 2021
Plasmodium vivax is the major cause of human malaria in the Americas. How P. vivax infection can lead to poor clinical outcomes, despite low peripheral parasitaemia, remains a matter of intense debate. Estimation of total P.
João L Silva-Filho, João CK Dos-Santos, Carla Judice, Dario Beraldi, Kannan Venugopal, Diogenes Lima, Helder I Nakaya, Erich V De Paula, Stefanie CP Lopes, Marcus VG Lacerda, Matthias Marti, Fabio TM Costa   +11 more
doaj   +1 more source

Plasma from Volunteers Breathing Helium Reduces Hypoxia-Induced Cell Damage in Human Endothelial Cells-Mechanisms of Remote Protection Against Hypoxia by Helium. [PDF]

, 2019
PurposeRemote ischemic preconditioning protects peripheral organs against prolonged ischemia/reperfusion injury via circulating protective factors. Preconditioning with helium protected healthy volunteers against postischemic endothelial dysfunction.
Augustijn, Quinten JJ, Hollmann, Markus W, Konkel, Moritz, Oei, Gezina TML, Patel, Hemal H, Preckel, Benedikt, Smit, Kirsten F, Weber, Nina C   +7 more
core   +1 more source

ACE-inhibition prevents postischemic coronary leukocyte adhesion and leukocyte-dependent reperfusion injury [PDF]

, 1997
Objective: Polymorphonuclear leukocytes (PMN), retained in the microvascular bed, can contribute to postischemic myocardial reperfusion injury. Since a beneficial effect of ACE-inhibition on reperfusion injury has been reported, we investigated the ...
Becker, Bernhard F., Gerlach, Eckehart, Habazettl, Helmut, Kupatt, Christian, Messmer, Konrad, Weber, Christian, Zahler, Stefan   +6 more
core   +1 more source

Endothelial Dysfunction in Obese Children [PDF]

National Journal of Laboratory Medicine, 2015
The magnitude of lifetime risk of cardiovascular disease (CVD) has radically increased along with the high prevalence of obesity in children.
Namrata Chhabra, Sahiba Kukreja , Sahil Chhabra, Sarah Chhabra, Kavish Ramessur   +4 more
doaj   +1 more source

Resistin Promotes Endothelial Cell Activation [PDF]

Circulation, 2003
Background— Adipocyte-derived hormones may represent a mechanism linking insulin resistance to cardiovascular disease. In the present study, we evaluated the direct effects of resistin, a novel adipocyte-derived hormone, on endothelial activation ...
Subodh, Verma, Shu-Hong, Li, Chao-Hung, Wang, Paul W M, Fedak, Ren-Ke, Li, Richard D, Weisel, Donald A G, Mickle   +6 more
openaire   +2 more sources