Results 181 to 190 of about 1,372,494 (310)

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

The effects of ENDOG on lipid metabolism may be tissue-dependent and may not require its translocation from mitochondria

Nature Communications
Marta Llovera, Leonor Gouveia, Antonio Zorzano, Daniel Sanchis   +3 more
doaj   +1 more source

Piezo1 specific deletion in endothelial cell protects the progression of pulmonary fibrosis in mice. [PDF]

Cell Commun Signal
He B, Tan Q, Xu H, Chen X, Wan R, Yao Y, Pan X, Liu S, Chen X, Jiang J, Luo S, An Y, Li J.   +12 more
europepmc   +1 more source

Fluid Forces Control Structural Remodeling of Blind‐Ended Lymphatic Microvessels

Advanced Healthcare Materials, EarlyView.
Using innovative microfluidic biofabrication with fluid mechanical insights, we recapitulated the blind‐ended microanatomy and physiological drainage properties of capillary lymphatics. Our results reveal the interrelationship between intra‐ and extraluminal regions of lymphatic vessels due to flow‐induced sprouting and morphological changes that ...
Jacob C. Holter, Shashwat S. Agarwal, Joseph W. Tinapple, Joseph M. Barlage, Travis H. Jones, Jonathan W. Song   +5 more
wiley   +1 more source

Endothelial cell-released CD93 contributes to podocyte injury in idiopathic nephrotic syndrome. [PDF]

Sci Transl Med
Bauer C, Piani F, Troost J, Da Sacco S, Rojas-Sanchez G, Davizon-Castillo P, Davizon-Castillo P, Perin L, Daehn I, Islam MI, Fetsko A, Carrera-Muñoz C, Rovin B, Zhang XL, Banks M, de Lucas-Collantes C, Ordóñez-Álvarez FA, Aparicio-López C, Lanaspa MA, Andres-Hernando A, Segarra A, Martinez C, Bjornstad P, Lucia MS, Schaefer F, Yilmaz A, Zurowska A, Wang X, McCown PJ, Eddy S, Hartman J, Mariani L, Kretzler M, Zhu Y, Bouts AHM, Levtchenko EN, Dougherty JA, Smoyer WE, Kerlin BA, Kallash M, Soranno DE, Cabrera-Sevilla JE, Gonzalez-Rodriguez JD, Siegele BJ, Tsuji S, Kaneko K, Sethna CB, Srivastava T, Bitzer M, O'Connor CL, Dimberg A, Zhao S, Yu L, Thurman JM, Johnson RJ, Cara-Fuentes G.   +55 more
europepmc   +1 more source

The Floor‐Ceiling‐Chip, or 2 × 2D = Pseudo‐3D—Approaching 3D Cell Morphology and Organization between Two Opposing 2D Substrates with Cell‐Adhesive Protein Micropatterns

Advanced Healthcare Materials, EarlyView.
Here, we present a novel 3D cell patterning and culture platform. The “Floor‐Ceiling‐Chip” (FC‐Chip) consists of two opposing track‐etched membranes, creating a pseudo‐3D microenvironment for the cells in between. By providing the membranes with micropatterned cell‐adhesive islands of varying geometries and sizes, the FC‐Chip enables control over cell ...
Urandelger Tuvshindorj, Francesca Giacomini, Esra Güben Kaçmaz, Tim ten Brink, Lorenzo Moroni, Zeinab Tahmasebi Birgani, Clemens van Blitterswijk, Pamela Habibović, Stefan Giselbrecht, Jan de Boer, Roman Truckenmüller   +10 more
wiley   +1 more source

Dual recombinase-mediated endothelial cell-specific lineage tracing and ablation. [PDF]

Cell Regen
Li J, Zhang M, Liu X, Zhang Z, Shi M, Pu W, Zhou B.   +6 more
europepmc   +1 more source

Laser‐Assisted Processing and Modification of Bioactive Glasses: A Review

Advanced Healthcare Materials, EarlyView.
Laser technologies provide powerful tools to process and transform bioactive glasses for advanced biomedical applications. This review discusses laser‐matter interaction mechanisms, laser surface engineering, and laser‐assisted fabrication of scaffolds and nanofibers.
Antonio Riveiro, Mario González‐Quintas, Mónica Fernández‐Arias, Jesús del Val, Félix Quintero, Rafael Comesaña, Fernando Lusquiños, Julian R. Jones, Juan Pou   +8 more
wiley   +1 more source

Talin1 modulates the Piezo1-YAP axis to regulate endothelial cell inflammation and atherosclerosis. [PDF]

Cell Mol Life Sci
Wang Y, Huang H, Liu Z, Gao Z, Liao B, Long Y, Yu F, Nie Y.   +7 more
europepmc   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source