Results 221 to 230 of about 1,372,494 (310)

ANGPT2/Tie2 Enhances H3K18la-Mediated Macrophage M2 Polarization to Promote Endothelial Cell Proliferation in the Chronically Ischaemic Brain. [PDF]

CNS Neurosci Ther
Tai C, Ling C, Yang Y, Mo N, Yao C, Lv S, Zhang B, Wang H, Chen C.   +8 more
europepmc   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Platelets induce endothelial cell mitochondrial dysfunction in myocardial infarction. [PDF]

Sci Adv
Sun H, Schlamp F, Muller M, Xia Y, Liberow S, Smilowitz NR, Hochman JS, Reynolds HR, Beckman JA, Barrett TJ, Berger JS.   +10 more
europepmc   +1 more source

Bioengineered 3D hPSC‐Cholangiocyte Ducts With Physiological Signals for Biliary Disease Modeling

Advanced Healthcare Materials, EarlyView.
Tian and colleagues generated a bioengineered bile duct from human pluripotent stem cell (hPSC)‐derived intrahepatic cholangiocytes within a high‐throughput, 384‐well platform to systematically examine the influence of biliary physiological signals including fluid flow, stromal cells and bile acids, and models intrahepatic biliary disease progression ...
Britney Tian, Mina Ogawa, Manami Kondo, Gabrielle Langeveld, Ling Jun Huan, Feng Zhang, Andrew Hollinger, Sara Deir, Christine Bear, Boyang Zhang, Shinichiro Ogawa   +10 more
wiley   +1 more source

Endothelial Cell-Based Vascular Bandages for Blood-Brain Barrier Repair and Targeted siRNA Delivery. [PDF]

Adv Sci (Weinh)
Li Y, Dong Y, He Y, Zheng J, Liu H, Li L, Hao X, Zhao Y, Yang Z, Sun Y, Du Z, Zhao B, Zhou W, Wu H, Zhang T, Wu J, Liu X, Yin X, Chen Z, Xue R, Lou M, Gu Z, Jiang X, Gao J.   +23 more
europepmc   +1 more source

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla García‐Iglesias, Jagoda Litowczenko, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

The role of aging on endothelial cell-cell junctions and pulmonary microvascular permeability in male mice. [PDF]

Physiol Rep
Manji A, Wang L, Pape C, Mehta S, Patel P, Yeung SC, Patterson EK, Dufour A, Young D, Veldhuizen RAW, Gill SE.   +10 more
europepmc   +1 more source

Endothelial cells

European Journal of Vascular and Endovascular Surgery, 1995
openaire   +1 more source

Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model

Advanced Healthcare Materials, EarlyView.
This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti, Cristina Richichi, Daniela Osti, Elena Ceccacci, Giovanni Bertalot, Camilla Cerutti, Giuseppina Giardina, Adriana Marinaro, Brunella Costanza, Valentina Gambino, Elena Zaccheroni, Daniela Tosoni, Maria G. Filippone, Marcello Del Corvo, Yinxiu Zhan, Teresa Gravina, Davide Corà, Monica Patanè, Bianca Pollo, Maria Giovanna Jodice, Salvatore Pece, Babette B. Weksler, Ignacio A. Romero, Pierre‐Olivier Couraud, Elisabetta Munzone, Massimiliano Del Bene, Francesco DiMeco, Giuliana Pelicci   +27 more
wiley   +1 more source

Extracellular vesicle miR-93-5p cargo regulates glomerular endothelial cell damage in Alport syndrome. [PDF]

JCI Insight
Dedhia C, Villani V, Hou X, Neviani P, Clair G, Kasravi M, Grange C, Cravedi P, Aguiari P, Alcala V, Orlando G, Song XY, Zuckerman JE, De Filippo RE, Da Sacco S, Sedrakyan S, Bussolati B, Perin L.   +17 more
europepmc   +1 more source