Results 51 to 60 of about 444,778 (249)
Taiwan Journal of Ophthalmology, 2017 PURPOSE: To compare endothelial cell density (ECD) loss rates in penetrating keratoplasty (PKP), Descemet's stripping automated endothelial keratoplasty (DSAEK), and deep anterior lamellar keratoplasty (DALK).
Bo-I Ku +5 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
EVALUATION OF CORNEAL ENDOTHELIAL CELLS AFTER PARS PLANA VITRECTOMY [PDF]
Zagazig University Medical Journal, 2018 Background: The corneal complications of vitreo-retinal surgery are rarely the primary concern of the surgeon operating on a difficult retinal detachment.
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Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Three-Year Effect of Phakic Intraocular Lenses on the Corneal Endothelial Cell Density
Clinical Ophthalmology, 2020 Yasmine Maher Shaaban, 1, 2 Tamer Abdel Fattah Badran 1, 2 1Department of Ophthalmology, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt; 2The Eye Subspecialty Center (ESC), Cairo 11402, EgyptCorrespondence: Yasmine Maher Shaaban 49 ...
Shaaban YM, Badran TAF
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Cardio-Oncology, 2018 Background Cancer survivors treated with thoracic ionizing radiation are at higher risk of premature death due to myocardial ischemia. No therapy is currently available to prevent or mitigate these effects.
Umesh C. Sharma +11 more
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Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Journal of Ophthalmology, 2018 Purpose. To review the risk factors and pathogenesis of endothelial decompensation after penetrating keratoplasty (PKP) and its novel therapeutic strategies. Methods. Literature review. Results.
Mengyuan Liu, Jing Hong
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FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
ERG preserves endothelial identity to limit atherosclerosis
Nature CommunicationsEndothelial function is a safeguard against atherosclerosis, yet endothelial‑to‑mesenchymal transition (EndMT) can occur at atheroprone sites. How endothelial identity loss contributes to atherogenesis remains unclear.
Steven R. Botts +19 more
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