Results 71 to 80 of about 27,105 (199)

Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID

Immunology, EarlyView.
The complement cascade, a series of blood proteins that assists in the recognition and neutralisation of pathogens, either independently or in conjunction with antibodies, is persistently activated in patients with long COVID. We found that blood plasma samples from patients with long COVID contained elevated concentrations of the mannan‐binding lectin‐
Samuel B. K. Keat, Priyanka Khatri, Youssif M. Ali, Chanuka H. Arachchilage, Gregory Demopulos, Kirsten Baillie, Kelly L. Miners, Kristin Ladell, Samantha A. Jones, Helen E. Davies, David A. Price, Wioleta M. Zelek, B. Paul Morgan, Wilhelm J. Schwaeble, Nicholas J. Lynch   +14 more
wiley   +1 more source

Methods for evaluating endothelial function: a position statement from the European Society of Cardiology Working Group on Peripheral Circulation [PDF]

, 2011
The endothelium holds a pivotal role in cardiovascular health and disease. Assessment of its function was until recently limited to experimental designs due to its location. The advent of novel techniques has facilitated testing on a more detailed basis,
Abraham, P, Balbarini, A, Blann, A, Boulanger, C M, Cockcroft, J, Cosentino, F, Deanfield, J, Gallino, A, Ikonomidis, I, Kremastinos, D, Landmesser, U, Lekakis, J, Protogerou, A, Stefanadis, C, Tousoulis, D, Vassalli, G, Vink, H, Vlachopoulos, C, Werner, N, Wilkinson, I   +19 more
core   +1 more source

Glycocalyx Damage Estimated Using Colloidal Iron Staining

Cell Transplantation, 2008
Anionic constituents in the peritubular capillary basement membranes and the glomerular endothelial cells have been demonstrated to function as a size- and charge-selective barrier.
Daoxin Zhang, Yoshitaka Isaka, Ryoichi Imamura, Naotsugu Ichimaru, Yi Shi, Enyu Imai, Ye Tian, Aiji Ohtsuka, Shiro Takahara   +8 more
doaj   +1 more source

Endothelial Dysfunction in Patients Undergoing Cardiac Surgery: A Narrative Review and Clinical Implications

Journal of Cardiovascular Development and Disease, 2023
Cardiac surgery is one of the highest-risk procedures, usually involving cardiopulmonary bypass and commonly inducing endothelial injury that contributes to the development of perioperative and postoperative organ dysfunction.
Danijel Knežević, Božena Ćurko-Cofek, Tanja Batinac, Gordana Laškarin, Marijana Rakić, Maja Šoštarič, Marko Zdravković, Alan Šustić, Vlatka Sotošek, Lara Batičić   +9 more
doaj   +1 more source

The Role of Brain Structure in Explaining Physical Functioning in Male Veterans With Impaired Kidney Function

Journal of the American Geriatrics Society, EarlyView.
Brain structure as a mediator of the relationship of impaired kidney function and physical function. ABSTRACT Background Older adults with chronic kidney disease (CKD) experience deficits in physical function and cardiorespiratory fitness at higher rates than older adults without impaired renal function.
Julie S. Rekant, Hinza B. Malik, Jamie E. Giffuni, Shari R. Waldstein, Kelly P. Westlake, Christos Davatzikos, Guray Erus, Stephen L. Seliger   +7 more
wiley   +1 more source

Multi-scale interaction of flow and the artery wall [PDF]

, 2009
We discuss, from the perspective of basic science, the physical and biological processes which underlie atherosclerotic (plaque) initiation at the vascular endothelium, identifying their widely separated spatial and temporal scales which participate.
2nd Micro and Nano Flows Conference (MNF2009), Atherton, MA, Care, CM, Collins, MW, Evans, D, Evans, PC, Halliday, I, Hose, DR, Khir, A, Krams, R, Lawford, PV, Lishchuk, SV, Ridger, V, Ventikos, Y, Walker, DC, Watton, PN   +15 more
core  

Dynamic interplay between breast cancer cells and normal endothelium mediates the expression of matrix macromolecules, proteasome activity and functional properties of endothelial cells [PDF]

, 2014
Background Breast cancer\u2013endothelium interactions provide regulatory signals facilitating tumor progression. The endothelial cells have so far been mainly viewed in the context of tumor perfusion and relatively little is known regarding the effects ...
Barbouri, D., Gialeli, C., Karamanos, N.K., Kletsas, D., Passi, A., Viola, M.   +5 more
core   +1 more source

Effects of Anti-Inflammatory Treatment and Surgical Intervention on Endothelial Glycocalyx, Peripheral and Coronary Microcirculatory Function and Myocardial Deformation in Inflammatory Bowel Disease Patients: A Two-Arms Two-Stage Clinical Trial [PDF]

, 2021
C Triantafyllou, Maria Nikolaou, Ignatios Ikonomidis, Giorgos Bamias, Demetrios Kouretas, Ioanna Andreadou, Maria Tsoumani, J Thymis, Ioannis Papaconstantinou   +8 more
openalex   +1 more source

Plasma supplemented with glycine is superior to standard plasma in reducing vascular permeability and organ injury via reduction of inflammation in an experimental traumatic shock model

Transfusion, EarlyView.
Abstract Background While plasma transfusion is a key resuscitation strategy, its mechanisms of benefit beyond coagulopathy correction remain unclear. Solvent detergent plasma, which contains high glycine levels and lacks inflammatory mediators, may offer advantages over fresh frozen plasma by preserving endothelial integrity and reducing inflammation.
Tarık Gözden, Bülent Ergin, Gözdenur Güneş, Ayşegül Kapucu, Nicole Juffermans   +4 more
wiley   +1 more source

Multiscale modeling of physical and biological systems [PDF]

, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
3rd Micro and Nano Flows Conference (MNF2011), Karniadakis, GE   +1 more
core