The Endothelial Glycocalyx as a Double-Edged Sword in Microvascular Homeostasis and Pathogenesis
Frontiers in Cell and Developmental Biology, 2021 Expressed on the endothelial cell (EC) surface of blood vessels, the glycocalyx (GCX), a mixture of carbohydrates attached to proteins, regulates the access of cells and molecules in the blood to the endothelium.
N. Villalba, Sheon Baby, S. Yuan
semanticscholar +1 more source
Endothelial glycocalyx: Role in body fluid homeostasis and fluid management [PDF]
, 2019 Endothelial glycocalyx layer (EGL) coating the luminal surface of vascular endothelium plays an essential role in maintaining the normal fluid homeostasis of the body.
Goswami, Shreya, Kundra, Pankaj
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Phenotypic and functional characterization of corneal endothelial cells during in vitro expansion. [PDF]
, 2020 The advent of cell culture-based methods for the establishment and expansion of human corneal endothelial cells (CEnC) has provided a source of transplantable corneal endothelium, with a significant potential to challenge the one donor-one recipient ...
Aldave, Anthony J +14 more
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Sulodexide counteracts endothelial dysfunction induced by metabolic or non-metabolic stresses through activation of the autophagic program [PDF]
, 2019 OBJECTIVE: Endothelial dysfunction (ED) predisposes to venous thrombosis (VT) and post-thrombotic syndrome (PTS), a long-term VT-related complication. Sulodexide (SDX) is a highly purified glycosaminoglycan with antithrombotic, pro-fibrinolytic and anti ...
Angelucci, A. +16 more
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Endothelial glycocalyx shields the interaction of SARS-CoV-2 spike protein with ACE2 receptors
Scientific Reports, 2021 Endothelial cells (ECs) play a crucial role in the development and propagation of the severe COVID-19 stage as well as multiorgan dysfunction. It remains, however, controversial whether COVID-19-induced endothelial injury is caused directly by the ...
M. Targosz-Korecka +5 more
semanticscholar +1 more source
Trauma Surgery & Acute Care Open, 2021 Objectives Patients with morbid obesity have impaired responses to resuscitation following severe injury, which may contribute to adverse outcomes.
David Edelman +3 more
doaj +1 more source
Advanced Functional Materials, EarlyView.This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput +5 more
wiley +1 more source
Endothelial pathophysiology, glycosaminoglycans and glycocalyx
Clinical Management Issues, 2015 The endothelial glycocalyx can be described as a network of membrane-bound proteoglycans and glycoproteins, covering the luminal surface of endothelial cells. Over the past decades, structural properties and functions of glycocalyx have been increasingly
Luca Masotti
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The Role of Heparin and Glycocalyx in Blood–Brain Barrier Dysfunction
Frontiers in Immunology, 2021 The blood-brain barrier (BBB) functions as a dynamic boundary that protects the central nervous system from blood and plays an important role in maintaining the homeostasis of the brain.
Rui Yang +4 more
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Transport of spheres suspended in the fluid flowing between hexagonally arranged cylinders [PDF]
, 2006 The motion of a spherical particle suspended in an incompressible Newtonian fluid flowing longitudinally between hexagonally arranged circular cylinders has been numerically analysed by a finite-element method in the Stokes flow regime.
Sugihara-seki Masako, 関 眞佐子
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