Results 51 to 60 of about 377,666 (204)
Endothelial Damage and the Microcirculation in Critical Illness
Biomedicines, 2022 Endothelial integrity maintains microcirculatory flow and tissue oxygen delivery. The endothelial glycocalyx is involved in cell signalling, coagulation and inflammation.
Rachael Cusack +3 more
doaj +1 more source
The Role of Plasma Transfusion in Massive Bleeding: Protecting the Endothelial Glycocalyx?
Frontiers in Medicine, 2018 Massive hemorrhage is a leading cause of death worldwide. During the last decade several retrospective and some prospective clinical studies have suggested a beneficial effect of early plasma-based resuscitation on survival in trauma patients.
Stefano Barelli +2 more
doaj +1 more source
Respiratory Research, 2021 Background Endothelial glycocalyx loss is integral to increased pulmonary vascular permeability in sepsis-related acute lung injury. Protectin conjugates in tissue regeneration 1 (PCTR1) is a novel macrophage-derived lipid mediator exhibiting potential ...
Xin-Yang Wang +9 more
doaj +1 more source
Applied Sciences, 2021 The aim was to explore the body of literature focusing on protective treatments against endothelial glycocalyx degradation in surgery. A comprehensive systematic review of relevant articles was conducted across databases.
Hasnain Q. R. B. Khan +1 more
doaj +1 more source
Matrix Biology Plus, 2022 The glycocalyx attached to the apical surface of vascular endothelial cells is a rich network of proteoglycans, glycosaminoglycans, and glycoproteins with instrumental roles in vascular homeostasis.
Danielle Pretorius +4 more
doaj +1 more source
Nanomechanics of the Endothelial Glycocalyx in Experimental Sepsis
PLoS ONE, 2013 The endothelial glycocalyx (eGC), a carbohydrate-rich layer lining the luminal side of the endothelium, regulates vascular adhesiveness and permeability. Although central to the pathophysiology of vascular barrier dysfunction in sepsis, glycocalyx damage has been generally understudied, in part because of the aberrancy of in vitro preparations and its ...
Wiesinger, V. (Véronique) +7 more
openaire +5 more sources
The glycocalyx as a permeability barrier: basic science and clinical evidence
Critical Care, 2022 Preclinical studies in animals and human clinical trials question whether the endothelial glycocalyx layer is a clinically important permeability barrier. Glycocalyx breakdown products in plasma mostly originate from 99.6–99.8% of the endothelial surface
Randal O. Dull, Robert G. Hahn
doaj +1 more source
Advanced Science, EarlyView.A biomimetic force‐electric nanotentacle‐enabled tantalum (Ta) implant with surface‐nanostructured LiTaO3 (n‐LiTaO3) was first developed via laser nanofabrication combined with Li+‐induced in situ reaction, enabling the transduction of ultrasound into bioelectrical cues.
Taixing Zhang +15 more
wiley +1 more source
Endothelial-erythrocyte glycocalyx exchange enables liquid biopsies of endothelial function
Nature CommunicationsThe luminal surface of blood vessels is covered by a hydrated mesh of sugars and proteins termed the endothelial glycocalyx. The glycocalyx forms a permeability barrier and helps regulate leucocyte migration.
Matthew J. Butler +18 more
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Scientific Reports, 2023 Endothelial dysfunction is an early event of vascular injury defined by a proinflammatory and procoagulant endothelial cell (EC) phenotype. Although endothelial glycocalyx disruption is associated with vascular damage, how various inflammatory stimuli ...
Anastasia Milusev +4 more
doaj +1 more source