Results 41 to 50 of about 377,666 (204)

The endothelial glycocalyx prefers albumin for evoking shear stress-induced, nitric oxide-mediated coronary dilatation [PDF]

open access: yes, 2007
Background: Shear stress induces coronary dilatation via production of nitric oxide ( NO). This should involve the endothelial glycocalyx ( EG). A greater effect was expected of albumin versus hydroxyethyl starch ( HES) perfusion, because albumin seals ...
Rehm, Markus   +7 more
core   +1 more source

Fibroblast growth factor 10 attenuates chronic obstructive pulmonary disease by protecting against glycocalyx impairment and endothelial apoptosis

open access: yesRespiratory Research, 2022
Highlights It is the first time to prove the confirm the endothelial glycocalyx impairment in COPD. FGF10 attenuates the development of emphysema and the shedding of glycocalyx induced by CSE in vivo.
Tian Jiang   +8 more
doaj   +1 more source

Targeting repair of the vascular endothelium and glycocalyx after traumatic injury with plasma and platelet resuscitation

open access: yesMatrix Biology Plus, 2022
Severely injured patients with hemorrhagic shock can develop endothelial dysfunction, systemic inflammation, and coagulation disturbances collectively known as the endotheliopathy of trauma (EOT). Shedding of the endothelial glycocalyx occurs early after
Mark Barry, Shibani Pati
doaj   +1 more source

Comparison of endothelial glycocalyx staining intensity.

open access: yes, 2021
IL-22:Fc treated mice have improved preservation of the endothelial glycocalyx in alveolar capillaries as compared to sham animals. Endothelial glycocalyx staining intensity was increased in the alveolar capillaries in IL-22:Fc treated mice after low ...
Alanna Wanek (11512968)   +9 more
core   +1 more source

Form follows function: The endothelial glycocalyx

open access: yesTranslational Research, 2022
Three types of capillaries, namely continuous, fenestrated, and sinusoidal, form the microvascular system; each type has a specialized structure and function to respond to the demands of the organs they supply. The endothelial glycocalyx, a gel-like layer of glycoproteins that covers the luminal surface of the capillary endothelium, is also thought to ...
Akio Suzuki   +2 more
openaire   +2 more sources

Endothelial Glycocalyx: Permeability Barrier and Mechanosensor [PDF]

open access: yesAnnals of Biomedical Engineering, 2011
Endothelial cells are covered with a polysaccharide rich layer more than 400 nm thick, mechanical properties of which limit access of circulating plasma components to endothelial cell membranes. The barrier properties of this endothelial surface layer are deduced from the rate of tracer penetration into the layer and the mechanics of red and white cell
F E, Curry, R H, Adamson
openaire   +2 more sources

Role of albumin in the preservation of endothelial glycocalyx integrity and the microcirculation: a review

open access: yesAnnals of Intensive Care, 2020
The endothelial glycocalyx comprises a complex layer of membrane-bound proteoglycans, secreted glycosaminoglycans, glycoproteins, glycolipids and bound plasma proteins such as albumin and antithrombin associated with the endothelial surface.
Cesar Aldecoa   +3 more
doaj   +1 more source

Case Report: Endothelial Glycocalyx Damage in Critically ill Patients With SARS-CoV-2-Related Multisystem Inflammatory Syndrome (MIS-C) [PDF]

open access: yes, 2021
Endothelial insult and damage is one of the reported consequences of SARS-CoV-2 infection. It has been associated with severe inflammation, thrombotic phenomena and profound hypoxemia in critically ill patients.
Jaime Fernández-Sarmiento   +20 more
core   +1 more source

The Glomerular Endothelium Restricts Albumin Filtration

open access: yesFrontiers in Medicine, 2021
Inflammatory activation and/or dysfunction of the glomerular endothelium triggers proteinuria in many systemic and localized vascular disorders. Among them are the thrombotic microangiopathies, many forms of glomerulonephritis, and acute inflammatory ...
Barbara J. Ballermann   +2 more
doaj   +1 more source

The endothelial glycocalyx: a review of the vascular barrier [PDF]

open access: yesAnaesthesia, 2014
Summary The endothelial glycocalyx is an important part of the vascular barrier. The glycocalyx is intimately linked to the homoeostatic functions of the endothelium. Damage to the glycocalyx precedes vascular pathology. In the first part of this paper, we have reviewed the structure, physiology and pathology of the endothelial ...
C S, Alphonsus, R N, Rodseth
openaire   +2 more sources

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