Results 81 to 90 of about 377,666 (204)
The Role of Heparin and Glycocalyx in Blood–Brain Barrier Dysfunction
Frontiers in Immunology, 2021 The blood-brain barrier (BBB) functions as a dynamic boundary that protects the central nervous system from blood and plays an important role in maintaining the homeostasis of the brain.
Rui Yang +4 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher +6 more
wiley +1 more source
Diabetic Medicine, EarlyView.Abstract Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is more severe in people with diabetes mellitus due to immune dysfunction, exacerbated inflammation and increased risk of co‐morbidities and mortality.
Taís Mendes Camargo +4 more
wiley +1 more source
The FEBS Journal, EarlyView.This study reveals that changes in the electrical charge, that is zeta potential of large extracellular vesicles (uEVs) found in urine, can reflect disease progression from diabetes to kidney scarring (fibrosis). With further clinical development, measurement of uEVs charge could provide a simple, noninvasive way to monitor disease progression and help
Melanie Tepuš +6 more
wiley +1 more source
Endothelial glycocalyx structure in human lung.
, 2019 Transmission electron microscopy was used to visualize the endothelial glycocalyx in the microvasculature of human lung tissue. Capillaries demonstrated varying levels of glycocalyx coverage, and the structure of the glycocalyx appeared to differ between
Jamie E. Meegan (6703580) +4 more
core +1 more source
The Endothelial Glycocalyx Protects Against Myocardial Edema [PDF]
Circulation Research, 2003 Myocardial tissue edema attributable to increased microvascular fluid loss contributes to cardiac dysfunction after myocardial ischemia, cardiopulmonary bypass, hypertension, and sepsis. Recent studies suggest that carbohydrate structures on the luminal surface of microvascular endothelium are essential to prevent tissue edema.
van den Berg, Bernard M. +2 more
openaire +3 more sources
The Endothelial Glycocalyx in Pig-to-Baboon Cardiac Xenotransplantation—First Insights
BiomedicinesCardiac xenotransplantation has seen remarkable success in recent years and is emerging as the most promising alternative to human cardiac allotransplantation.
Martin Bender +23 more
doaj +1 more source
Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence
Journal of Periodontal Research, EarlyView.This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo +3 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend New approach methodologies (NAMs) to test the pharmaco‐ and chemicokinetics of compound transfer across the human placental barrier in late pregnancy. Abstract This review addresses an important and timely topic at the intersection of placental biology with respect to barrier transfer kinetics, toxicology and mathematical ...
Paul Brownbill, Eleanor Doman
wiley +1 more source
Glycocalyx Damage Estimated Using Colloidal Iron Staining
Cell Transplantation, 2008 Anionic constituents in the peritubular capillary basement membranes and the glomerular endothelial cells have been demonstrated to function as a size- and charge-selective barrier.
Daoxin Zhang +8 more
doaj +1 more source