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Endothelial stem and progenitor cells (stem cells): (2017 Grover Conference Series) [PDF]

open access: yesPulmonary Circulation, 2017
The capacity of existing blood vessels to give rise to new blood vessels via endothelial cell sprouting is called angiogenesis and is a well-studied biologic process.
Mervin C. Yoder
doaj   +5 more sources

Current concepts on endothelial stem cells definition, location, and markers

open access: yesStem Cells Translational Medicine, 2021
Ischemic vascular disease is a major cause of mortality and morbidity worldwide, and regeneration of blood vessels in perfusion‐deficient tissues is a worthwhile therapeutic goal. The idea of delivering endothelial stem/progenitor cells to repair damaged
Sarah E.J. Chambers   +8 more
doaj   +2 more sources

Endothelial cells derived from human embryonic stem cells [PDF]

open access: greenProceedings of the National Academy of Sciences, 2002
Human embryonic stem cells have the potential to differentiate into various cell types and, thus, may be useful as a source of cells for transplantation or tissue engineering. We describe here the differentiation steps of human embryonic stem cells into endothelial cells forming vascular-like structures.
Shulamit Levenberg   +4 more
openalex   +5 more sources

Targeting mesenchymal stem cells to activated endothelial cells [PDF]

open access: greenBiomaterials, 2009
Cell surface coating is a methodology wherein specific molecules are transiently anchored onto cell membrane to modulate cell behavior. Cell surface coating was tested as a method to deliver mesenchymal stem cells (MSCs) to endothelial cells via binding to intercellular cell adhesion molecule-1 (ICAM-1).
In Kap Ko   +2 more
openalex   +4 more sources

Production of bioactive cytokines using plant expression system for cardiovascular cell differentiation from human pluripotent stem cells [PDF]

open access: yesStem Cell Research & Therapy
Bioactive cytokines such as vascular endothelial growth factor (VEGF) and Activin A are critical for the differentiation of stem cells into vascular endothelial cells and cardiomyocytes. However, production of the cytokines using conventional Escherichia
Kozue Murata   +6 more
doaj   +2 more sources

CD157+ vascular endothelial cells derived from human-induced pluripotent stem cells have high angiogenic potential [PDF]

open access: yesInflammation and Regeneration
Background We previously reported that a vascular endothelial stem cell population resides in pre-existing blood vessels in mice and may contribute to vascular endothelial cells in liver injury or hind limb ischemia models in the long-term.
Ami Takii   +7 more
doaj   +2 more sources

Endothelial cell dysfunction: a key determinant for the outcome of allogeneic stem cell transplantation

open access: yesBone Marrow Transplantation, 2021
Allogeneic hematopoietic stem cell transplantation (alloSCT) carries the promise of cure for many malignant and non-malignant diseases of the lympho-hematopoietic system.
T. Luft, P. Dreger, A. Radujkovic
semanticscholar   +1 more source

Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing

open access: yesStem cell research & therapeutics, 2023
Wound healing is a dynamic and highly sequential process involving a series of overlapping spatial and temporal phases, including hemostasis, inflammation, proliferation, and tissue remodeling.
Chuchao Zhou   +7 more
semanticscholar   +1 more source

Comparative Analysis of Blood‐Derived Endothelial Cells for Designing Next‐Generation Personalized Organ‐on‐Chips

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Organ‐on‐chip technology has accelerated in vitro preclinical research of the vascular system, and a key strength of this platform is its promise to impact personalized medicine by providing a primary human cell–culture environment where ...
Tanmay Mathur   +2 more
doaj   +1 more source

Induction of Neurogenesis and Angiogenesis in a Rat Hemisection Spinal Cord Injury Model With Combined Neural Stem Cell, Endothelial Progenitor Cell, and Biomimetic Hydrogel Matrix Therapy

open access: yesCritical Care Explorations, 2021
OBJECTIVES:. Acute spinal cord injury is a devastating injury that may lead to loss of independent function. Stem-cell therapies have shown promise; however, a clinically efficacious stem-cell therapy has yet to be developed.
Eric J. Marrotte, DO, PhD   +6 more
doaj   +1 more source

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