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Advancements in Cellular Therapeutics in Corneal Diseases [PDF]
CellsDisorders of the cornea are responsible for a significant portion of preventable blindness worldwide. Various types of corneal transplantation procedures have successfully restored vision in many individuals; however, they carry the risk of graft failure
Elizabeth Woo +2 more
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CD157+ vascular endothelial cells derived from human-induced pluripotent stem cells have high angiogenic potential [PDF]
Inflammation and RegenerationBackground We previously reported that a vascular endothelial stem cell population resides in pre-existing blood vessels in mice and may contribute to vascular endothelial cells in liver injury or hind limb ischemia models in the long-term.
Ami Takii +7 more
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Organ‐on‐chip technology has accelerated in vitro preclinical research of the vascular system, and a key strength of this platform is its promise to impact personalized medicine by providing a primary human cell–culture environment where ...
Tanmay Mathur +2 more
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Caspases and p38 MAPK regulate endothelial cell adhesiveness for mesenchymal stem cells. [PDF]
PLoS ONE, 2013 Mesenchymal stem cells natively circulating or delivered into the blood stream home to sites of injury. The mechanism of mesenchymal stem cell homing to sites of injury is poorly understood.
Irina A Potapova +2 more
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Critical Care Explorations, 2021 OBJECTIVES:. Acute spinal cord injury is a devastating injury that may lead to loss of independent function. Stem-cell therapies have shown promise; however, a clinically efficacious stem-cell therapy has yet to be developed.
Eric J. Marrotte, DO, PhD +6 more
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Frontiers in Bioengineering and Biotechnology, 2021 Failure of corneal endothelium cell monolayer is the main cause leading to corneal transplantation. Autologous cell-based therapies are required to reconstruct in vitro the cell monolayer.
Begoña M. Bosch +5 more
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Current concepts on endothelial stem cells definition, location, and markers
Stem Cells Translational Medicine, 2021 Ischemic vascular disease is a major cause of mortality and morbidity worldwide, and regeneration of blood vessels in perfusion‐deficient tissues is a worthwhile therapeutic goal. The idea of delivering endothelial stem/progenitor cells to repair damaged
Sarah E.J. Chambers +8 more
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Placental growth factor expression is required for bone marrow endothelial cell support of primitive murine hematopoietic cells. [PDF]
PLoS ONE, 2013 Two distinct microenvironmental niches that regulate hematopoietic stem/progenitor cell physiology in the adult bone marrow have been proposed; the endosteal and the vascular niche.
Xiaoying Zhou +2 more
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A Novel Molecular and Functional Stemness Signature Assessing Human Cord Blood-Derived Endothelial Progenitor Cell Immaturity. [PDF]
PLoS ONE, 2016 Endothelial Colony Forming Cells (ECFCs), a distinct population of Endothelial Progenitor Cells (EPCs) progeny, display phenotypic and functional characteristics of endothelial cells while retaining features of stem/progenitor cells.
Oriane Guillevic +5 more
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Frontiers in Bioengineering and Biotechnology, 2021 The long-term co-culture of mouse embryonic stem cells (mESC) with rat endothelial cells (EC) was tested for contact differentiation into the endothelial lineage.
Marina Valentinovna Kovina +7 more
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