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Endothelial stem and progenitor cells (stem cells): (2017 Grover Conference Series) [PDF]

Pulmonary Circulation, 2017
The capacity of existing blood vessels to give rise to new blood vessels via endothelial cell sprouting is called angiogenesis and is a well-studied biologic process.
Mervin C. Yoder
doaj   +6 more sources

Endothelial induced EMT in breast epithelial cells with stem cell properties. [PDF]

PLoS ONE, 2011
Epithelial to mesenchymal transition (EMT) is a critical event in cancer progression and is closely linked to the breast epithelial cancer stem cell phenotype.
Valgardur Sigurdsson, Bylgja Hilmarsdottir, Hekla Sigmundsdottir, Agla J R Fridriksdottir, Markus Ringnér, Rene Villadsen, Ake Borg, Bjarni A Agnarsson, Ole William Petersen, Magnus K Magnusson, Thorarinn Gudjonsson   +10 more
doaj   +10 more sources

Endothelial cells derived from human embryonic stem cells [PDF]

Proceedings of the National Academy of Sciences, 2002
Human embryonic stem cells have the potential to differentiate into various cell types and, thus, may be useful as a source of cells for transplantation or tissue engineering. We describe here the differentiation steps of human embryonic stem cells into endothelial cells forming vascular-like structures.
Shulamit Levenberg, Justin S. Golub, Michal Amit, Joseph Itskovitz‐Eldor, Róbert Langer   +4 more
openalex   +5 more sources

Targeting mesenchymal stem cells to activated endothelial cells [PDF]

Biomaterials, 2009
Cell surface coating is a methodology wherein specific molecules are transiently anchored onto cell membrane to modulate cell behavior. Cell surface coating was tested as a method to deliver mesenchymal stem cells (MSCs) to endothelial cells via binding to intercellular cell adhesion molecule-1 (ICAM-1).
In Kap Ko, Thomas J. Kean, James E. Dennis   +2 more
openalex   +4 more sources

Production of bioactive cytokines using plant expression system for cardiovascular cell differentiation from human pluripotent stem cells [PDF]

Stem Cell Research & Therapy
Bioactive cytokines such as vascular endothelial growth factor (VEGF) and Activin A are critical for the differentiation of stem cells into vascular endothelial cells and cardiomyocytes. However, production of the cytokines using conventional Escherichia
Kozue Murata, Kanae Takamura, Risa Watanabe, Akitomo Nagashima, Miho Miyauchi, Yoshiteru Miyauchi, Hidetoshi Masumoto   +6 more
doaj   +2 more sources

Comparative Analysis of Blood‐Derived Endothelial Cells for Designing Next‐Generation Personalized Organ‐on‐Chips

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Organ‐on‐chip technology has accelerated in vitro preclinical research of the vascular system, and a key strength of this platform is its promise to impact personalized medicine by providing a primary human cell–culture environment where ...
Tanmay Mathur, James J. Tronolone, Abhishek Jain   +2 more
doaj   +1 more source

Induction of Neurogenesis and Angiogenesis in a Rat Hemisection Spinal Cord Injury Model With Combined Neural Stem Cell, Endothelial Progenitor Cell, and Biomimetic Hydrogel Matrix Therapy

Critical Care Explorations, 2021
OBJECTIVES:. Acute spinal cord injury is a devastating injury that may lead to loss of independent function. Stem-cell therapies have shown promise; however, a clinically efficacious stem-cell therapy has yet to be developed.
Eric J. Marrotte, DO, PhD, Khari Johnson, MS, Ryan M. Schweller, PhD, Rachel Chapla, MS, Brian E. Mace, BS, Daniel T. Laskowitz, MD, Jennifer L. West, PhD   +6 more
doaj   +1 more source

Caspases and p38 MAPK regulate endothelial cell adhesiveness for mesenchymal stem cells. [PDF]

PLoS ONE, 2013
Mesenchymal stem cells natively circulating or delivered into the blood stream home to sites of injury. The mechanism of mesenchymal stem cell homing to sites of injury is poorly understood.
Irina A Potapova, Ira S Cohen, Sergey V Doronin   +2 more
doaj   +1 more source

Mesenchymal Stem Cells & Endothelial Function [PDF]

EBioMedicine, 2015
In this issue of EBioMedicine, Premer et al. report their study titled “Allogeneic Mesenchymal Stem Cells Restore Endothelial Function in Heart Failure by Stimulating Endothelial Progenitor Cells” (Premer et al., 2015). They recruited a cohort of heart failure patients from two ongoing clinical trials evaluating both autologous and allogeneic ...
Roger J. Hajjar, Kenneth Fish
openaire   +4 more sources

Endothelial origin of mesenchymal stem cells [PDF]

Cell Cycle, 2011
Mesenchymal stem/stromal cells (MSCs) are fibroblastoid cells capable of long-term expansion and skeletogenic differentiation. While MSCs are known to originate from neural crest and mesoderm, immediate mesodermal precursors that give rise to MSCs have not been characterized.
Maxim A. Vodyanik, Igor I. Slukvin
openaire   +3 more sources