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Endothelial stem and progenitor cells (stem cells): (2017 Grover Conference Series) [PDF]

open access: yesPulmonary Circulation, 2017
The capacity of existing blood vessels to give rise to new blood vessels via endothelial cell sprouting is called angiogenesis and is a well-studied biologic process.
Mervin C. Yoder
doaj   +7 more sources

Current concepts on endothelial stem cells definition, location, and markers

open access: yesStem Cells Translational Medicine, 2021
Ischemic vascular disease is a major cause of mortality and morbidity worldwide, and regeneration of blood vessels in perfusion‐deficient tissues is a worthwhile therapeutic goal. The idea of delivering endothelial stem/progenitor cells to repair damaged
Sarah E.J. Chambers   +8 more
doaj   +2 more sources

Endothelial induced EMT in breast epithelial cells with stem cell properties. [PDF]

open access: yesPLoS ONE, 2011
Epithelial to mesenchymal transition (EMT) is a critical event in cancer progression and is closely linked to the breast epithelial cancer stem cell phenotype.
Valgardur Sigurdsson   +10 more
doaj   +9 more sources

CD157+ vascular endothelial cells derived from human-induced pluripotent stem cells have high angiogenic potential [PDF]

open access: yesInflammation and Regeneration
Background We previously reported that a vascular endothelial stem cell population resides in pre-existing blood vessels in mice and may contribute to vascular endothelial cells in liver injury or hind limb ischemia models in the long-term.
Ami Takii   +7 more
doaj   +2 more sources

Pathogen sensing pathways in human embryonic stem cell derived-endothelial cells: role of NOD1 receptors. [PDF]

open access: yesPLoS ONE, 2014
Human embryonic stem cell-derived endothelial cells (hESC-EC), as well as other stem cell derived endothelial cells, have a range of applications in cardiovascular research and disease treatment.
Daniel M Reed   +16 more
doaj   +5 more sources

Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing

open access: yesStem cell research & therapeutics, 2023
Wound healing is a dynamic and highly sequential process involving a series of overlapping spatial and temporal phases, including hemostasis, inflammation, proliferation, and tissue remodeling.
Chuchao Zhou   +7 more
semanticscholar   +1 more source

Comparative Analysis of Blood‐Derived Endothelial Cells for Designing Next‐Generation Personalized Organ‐on‐Chips

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Organ‐on‐chip technology has accelerated in vitro preclinical research of the vascular system, and a key strength of this platform is its promise to impact personalized medicine by providing a primary human cell–culture environment where ...
Tanmay Mathur   +2 more
doaj   +1 more source

Induction of Neurogenesis and Angiogenesis in a Rat Hemisection Spinal Cord Injury Model With Combined Neural Stem Cell, Endothelial Progenitor Cell, and Biomimetic Hydrogel Matrix Therapy

open access: yesCritical Care Explorations, 2021
OBJECTIVES:. Acute spinal cord injury is a devastating injury that may lead to loss of independent function. Stem-cell therapies have shown promise; however, a clinically efficacious stem-cell therapy has yet to be developed.
Eric J. Marrotte, DO, PhD   +6 more
doaj   +1 more source

Caspases and p38 MAPK regulate endothelial cell adhesiveness for mesenchymal stem cells. [PDF]

open access: yesPLoS ONE, 2013
Mesenchymal stem cells natively circulating or delivered into the blood stream home to sites of injury. The mechanism of mesenchymal stem cell homing to sites of injury is poorly understood.
Irina A Potapova   +2 more
doaj   +1 more source

Discovering the Potential of Dental Pulp Stem Cells for Corneal Endothelial Cell Production: A Proof of Concept

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Failure of corneal endothelium cell monolayer is the main cause leading to corneal transplantation. Autologous cell-based therapies are required to reconstruct in vitro the cell monolayer.
Begoña M. Bosch   +5 more
doaj   +1 more source

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