Results 121 to 130 of about 1,271,424 (340)

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

open access: yesAdvanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran   +5 more
wiley   +1 more source

Effects of concentrated growth factor on proliferation, migration, and differentiation of human dental pulp stem cells in vitro

open access: yesJournal of Tissue Engineering, 2018
Concentrated growth factor, a novel autologous plasma extract, contained various growth factors which promoted tissue regeneration. In this study, we aimed to investigate the biological effects of concentrated growth factor on human dental pulp stem ...
Runze Jin   +5 more
doaj   +1 more source

Loss of endothelial thrombomodulin predicts response to steroid therapy and survival in acute intestinal graft-versus-host disease

open access: yesHaematologica, 2012
Steroid-refractory graft-versus-host disease causes significant morbidity and mortality after allogeneic stem cell transplantation. The pathomechanism of steroid resistance is currently not understood, but it has been suggested that endothelial cell ...
Mindaugas Andrulis   +9 more
doaj   +1 more source

Step‐wise divergence of primitive and definitive haematopoietic and endothelial cell lineages during embryonic stem cell differentiation [PDF]

open access: bronze, 2001
Tetsuhiro Fujimoto   +6 more
openalex   +1 more source

Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?

open access: yesAdvanced Biology, EarlyView.
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez   +3 more
wiley   +1 more source

Pathogen sensing pathways in human embryonic stem cell derived-endothelial cells: role of NOD1 receptors.

open access: yesPLoS ONE, 2014
Human embryonic stem cell-derived endothelial cells (hESC-EC), as well as other stem cell derived endothelial cells, have a range of applications in cardiovascular research and disease treatment.
Daniel M Reed   +16 more
doaj   +1 more source

From hemangioblast to hematopoietic stem cell: An endothelial connection?

open access: yesExperimental Hematology, 2005
The developmental origin of hematopoietic stem cells has been the subject of much research. Now that the developmental link between the hematopoietic system and the vasculature has been well established, questions remain regarding the precise cellular origin of definitive hematopoietic cells and at what point they branch off from the endothelial ...
Jaffredo, T   +5 more
openaire   +4 more sources

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

open access: yesAdvanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali   +5 more
wiley   +1 more source

Notch1 but Not Notch2 Is Essential for Generating Hematopoietic Stem Cells from Endothelial Cells [PDF]

open access: bronze, 2003
Keiki Kumano   +12 more
openalex   +1 more source

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

open access: yesAdvanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht   +5 more
wiley   +1 more source

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