eNOS transfection of adipose-derived stem cells yields bioactive nitric oxide production and improved results in vascular tissue engineering. [PDF]
, 2015 This study evaluates the durability of a novel tissue engineered blood vessel (TEBV) created by seeding a natural vascular tissue scaffold (decellularized human saphenous vein allograft) with autologous adipose-derived stem cells (ASC) differentiated ...
Bagameri, Gabor +10 more
core +2 more sources
PDGFD switches on stem cell endothelial commitment
Angiogenesis, 2022 AbstractThe critical factors regulating stem cell endothelial commitment and renewal remain not well understood. Here, using loss- and gain-of-function assays together with bioinformatic analysis and multiple model systems, we show that PDGFD is an essential factor that switches on endothelial commitment of embryonic stem cells (ESCs).
Weisi Lu +19 more
openaire +2 more sources
Persistence of recipient-type endothelium after allogeneic hematopoietic stem cell transplantation
Haematologica, 2011 Background The possibility that allogeneic hematopoietic stem cell transplantation performed across the ABO blood group-barrier is associated with an increase of graft-versus-host disease, in particular endothelial damage, has not been elucidated so far.
Regula J. Mueller +12 more
doaj +1 more source
Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia [PDF]
, 2006 Background— Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of ischemic tissue. Enhanced tissue expression of chemoattractant factors such as stromal cell–derived factor 1 and vascular endothelial growth ...
Aicher, A +5 more
core +1 more source
PLoS ONE, 2022 Cardiomyocyte proliferation has emerged as the main source of new cardiomyocytes in the adult. Progenitor cell populations may on the other hand contribute to the renewal of other cell types, including endothelial and smooth muscle cells.
Mikael Sandstedt +8 more
doaj +3 more sources
Insulin-like growth factors promote vasculogenesis in embryonic stem cells. [PDF]
PLoS ONE, 2012 The ability of embryonic stem cells to differentiate into endothelium and form functional blood vessels has been well established and can potentially be harnessed for therapeutic angiogenesis.
Stephanie M Piecewicz +5 more
doaj +1 more source
Evaluation of Endothelial Cells Differentiated from Amniotic Fluid-Derived Stem Cells [PDF]
, 2012 Amniotic fluid holds great promise as a stem cell source, especially in neonatal applications where autologous cells can be isolated and used. This study examined chemical-mediated differentiation of amniotic fluid-derived stem cells (AFSC) into ...
Anthony Johnson +5 more
core +1 more source
Differentiation of pluripotent stem cells into endothelial cells [PDF]
Current Opinion in Hematology, 2015 Methods to isolate endothelial cells from murine and human pluripotent stem cells continue to evolve and increasingly diverse endothelial cell populations have been generated. This review provides an update of key articles published within the past year that report on some of those advances.Cooperative interactions among microRNA (miRNA), transcription
openaire +4 more sources
Stem Cell Research & Therapy, 2018 Autophagy plays a critical role in the dynamic growth of each cell through different conditions. It seems that this intracellular mechanism acts as a two-edged sword against the numerous cell insults. Previously, autophagy was described in the context of
Mehdi Hassanpour +4 more
doaj +1 more source
Improved arteriogenesis with simultaneous skeletal muscle repair in ischemic tissue by SCL plus multipotent adult progenitor cell clones from peripheral blood [PDF]
, 2004 Background: The CD34- murine stem cell line RM26 cloned from peripheral blood mononuclear cells has been shown to generate hematopoietic progeny in lethally irradiated animals.
Gottgens, Berthold +7 more
core +1 more source