Results 121 to 130 of about 16,284 (266)

Environmental modulators of vascular physiology and inflammation

open access: yesExperimental Physiology, EarlyView.
Abstract Environmental factors play a crucial role in modulating vascular inflammation, contributing significantly to the development of atherosclerosis and cardiovascular disease. This review synthesizes current evidence on how various environmental exposures influence vascular function and inflammation, with a focus on pollutants such as particulate ...
Anusha N. Seneviratne   +3 more
wiley   +1 more source

Role of the endothelin receptor antagonist bosentan in the treatment of patients with pulmonary hypertension

open access: yesТерапевтический архив, 2013
The paper reviews current views of the problem of pulmonary hypertension. It shows the classification of pulmonary hypertension and considers the general issues of its pathogenesis, morphological changes, clinical picture, and main approaches to treating
N A Tsareva
doaj  

Chronic Effects of a Novel, Orally Active Endothelin Receptor Antagonist, T-0201, in Dogs with Congestive Heart Failure

open access: bronze, 1998
Masato Ohnishi   +6 more
openalex   +1 more source

Impact of acute caffeine intake on local tolerance to cold before and after total sleep deprivation

open access: yesExperimental Physiology, EarlyView.
Abstract Total sleep deprivation (TSD) alters local cold tolerance and could thus increase the risk of cold injury. We evaluated the impact of acute caffeine intake, the main countermeasure to TSD‐related deleterious effects, on local cold tolerance before and after TSD.
Baptiste de Lorgeril   +11 more
wiley   +1 more source

Safety, efficacy, and clinical utility of macitentan in the treatment of pulmonary arterial hypertension

open access: yesDrug Design, Development and Therapy, 2016
Thomas J Monaco,1 Carlos D Davila2 1Division of Pulmonary and Critical Care Medicine, Baylor College of Medicine, Houston, TX, 2Department of Medicine, Einstein Medical Center, Philadelphia, PA, USA Abstract: Pulmonary arterial hypertension is a ...
Monaco TJ, Davila CD
doaj  

Endothelin receptor antagonists for pulmonary arterial hypertension and COVID-19: Friend or foe? [PDF]

open access: yesJ Heart Lung Transplant, 2020
Badagliacca R, Sciomer S, Petrosillo N.
europepmc   +1 more source

Cyclic Pentapeptide Endothelin A Receptor Antagonists with Attenuated in Vivo Clearance.

open access: bronze, 1996
Tatsuki Fukami   +7 more
openalex   +2 more sources

ESM‐1 and GBP‐1 are associated with endothelial dysfunction: emerging biomarkers or key players in the pathophysiology of preeclampsia?

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Endothelial specific molecule‐1 (ESM‐1) and guanylate binding protein‐1 (GBP‐1) are proteins that are produced by activated/dysfunctional endothelial cells and are increased and decreased, respectively, during preeclampsia. It remains to be established whether ESM‐1 and GBP‐1 could potentially be included as biomarkers for the ...
Ines Pronk   +3 more
wiley   +1 more source

Excessive hypercholesterolaemia during pregnancy as a risk factor for endothelial dysfunction in pre‐eclampsia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy