Results 11 to 20 of about 36,666 (331)
Digestion, 1998 Accessible online at: http://BioMedNet.com/karger Hyperdynamic circulation as well as increased hepatic resistance contribute to portal hypertension in cirrhosis of the liver [1]. Hyperdynamic circulation with increased cardiac output, heart rate and plasma volume and decreased arterial blood pressure and systemic vascular resistance are characteristic
Bilzer, Manfred +2 more
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Pharmacological Reviews, 2016 The endothelins comprise three structurally similar 21-amino acid peptides. Endothelin-1 and -2 activate two G-protein coupled receptors, ETA and ETB, with equal affinity, whereas endothelin-3 has a lower affinity for the ETA subtype. Genes encoding the peptides are present only among vertebrates.
Davenport, Anthony P +8 more
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Cellular and Molecular Life Sciences, 2010 Endothelin-1 is the most potent vasoconstrictor agent currently identified, and it was originally isolated and characterized from the culture media of aortic endothelial cells. Two other isoforms, termed endothelin-2 and endothelin-3, were subsequently identified, along with structural homologues isolated from the venom of Actractapis engaddensis known
Kawanabe, Yoshifumi, Nauli, Surya M.
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The Role of Endothelins, IL-18, and NGAL in Kidney Hypothermic Machine Perfusion
Biomedicines, 2021 Ischemia-reperfusion injury (IRI) occurring after renal transplantation is a complex biochemical process that can be monitored by specific biomarkers. The roles of those are not yet fully elucidated.
Karol Tejchman +7 more
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Endothelins and Sarafotoxins: Peptides of Similar Structure and Different Function
Acta Medica, 2004 Endothelins are endogenous vasoactive peptides that are considered among the most potent vasoconstrictor substances known. In addition to their vascular effects, endothelins and their receptors have been shown to be present in many organs and share ...
Jiří Patočka +3 more
doaj +1 more source
Endothelin B Receptors on Primary Chicken Müller Cells and the Human MIO-M1 Müller Cell Line Activate ERK Signaling via Transactivation of Epidermal Growth Factor Receptors. [PDF]
PLoS ONE, 2016 Injury to the eye or retina triggers Müller cells, the major glia cell of the retina, to dedifferentiate and proliferate. In some species they attain retinal progenitor properties and have the capacity to generate new neurons. The epidermal growth factor
Mohammad Harun-Or-Rashid +3 more
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Insights from Amphioxus into the Evolution of Vertebrate Cartilage [PDF]
, 2007 Central to the story of vertebrate evolution is the origin of the vertebrate head, a problem difficult to approach using paleontology and comparative morphology due to a lack of unambiguous intermediate forms. Embryologically, much of the vertebrate head
A Beverdam +57 more
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Endothelin and the podocyte [PDF]
Clinical Kidney Journal, 2012 In the past decade, research has advanced our understanding how endothelin contributes to proteinuria and glomerulosclerosis. Data from pre-clinical and clinical studies now provide evidence that proteinuric diseases such as focal segmental glomerulosclerosis and diabetic nephropathy as well as hypertension nephropathy are sensitive to treatment with ...
Matthias Barton, Pierre-Louis Tharaux
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Zaporožskij Medicinskij Žurnal, 2019 The impact of infusion solutions on endothelial damage correction in acute ischemic stroke (AIS) remains an insufficiently studied. Purpose. To investigate the dynamics of endothelin-1 as one of the main markers of vasoconstriction and endothelial ...
A. I. Semenenko +5 more
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Endothelin receptor antagonists for the treatment of pulmonary artery hypertension [PDF]
, 2012 AimsThe demonstration that endothelin production is upregulated in pulmonary artery hypertension (PAH) served as the rationale for developing endothelin-receptor antagonists (ERAs) as a treatment for PAH.
Komaromy, David +5 more
core +2 more sources