Results 31 to 40 of about 4,400 (309)

Connective tissue remodeling: cross-talk between endothelins and matrix metalloproteinases.

, 2005
Connective tissue remodeling is achieved by a complex process involving several cell types, a plethora of growth factors, cytokines, chemokines and turnover of extracellular matrix (ECM).
Nagase, H, Abraham, D, Ponticos, M, Nagase, Hideaki   +3 more
core   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Identification of endothelin-1, endothelin-2 and endothelin-3 in human endometrium [PDF]

Reproduction, 1993
This study determined the presence of specific endothelin isoforms in human endometrium using high performance liquid chromatography (HPLC) combined with radioimmunoassay, and immunocytochemistry to detect the endothelin precursors (proendothelin-1, proendothelin-2 and proendothelin-3).
I T, Cameron, C, Plumpton, R, Champeney, C, van Papendorp, M J, Ashby, A P, Davenport   +5 more
openaire   +2 more sources

Endothelin-1 Production by Normal Human Cultured Keratinocytes and its Regulation

Mediators of Inflammation, 1994
The possibility that cultured keratinocytes produce endothelins were investigated. The results showed that cultured keratinocytes derived from normal human skin produce endothelin-1. Moreover, keratinocyte endothelin-1 production was completely inhibited
Hajime Inoue, Nagaoki Wakisaka, Nobuhiro Tane, Kazumasa Ando, Emiko Isono, Miwa Yamanaka, Masaki Aihara, Hirotomo Ishida   +7 more
doaj   +1 more source

Endothelin XII

Life Sciences, 2012
Following the initial description of endothelium-dependent vasoconstriction in the early 1980s, it has been exactly 25 years since efforts to identify the sequence of the endothelin gene and peptide began in May 1987, work which resulted in a landmark paper submitted to Nature in December 1987 and published on March 31, 1988.
Yanagisawa, M, Masaki, T, Vanhoutte, PM, Barton, M   +3 more
openaire   +4 more sources

An Integrated Pathogenetic Model of Primary Biliary Cholangitis

Livers
The pathogenesis of primary biliary cholangitis (PBC) is not fully understood. Despite recent progress, many aspects require further clarification. Thus, PBC is regarded as an autoimmune disease, but immunosuppressive treatment, which is effective in ...
Elias Kouroumalis, Ioannis Tsomidis, Argyro Voumvouraki   +2 more
doaj   +1 more source

The Kallikrein-Kinin-System in Experimental Chagas Disease: A Paradigm to Investigate the Impact of Inflammatory Edema on GPCR-mediated pathways of Host Cell Invasion by Trypanosoma cruzi

Frontiers in Immunology, 2013
Chronic chagasic myocarditis (CCM) depends on Trypanosoma cruzi persistence in the myocardium. Studies of the proteolytic mechanisms governing host/parasite balance in peripheral sites of T.
Julio eScharfstein, Daniele eAndrade, Erik eSvensjö, Ana Carolina eOliveira, Clarissa Rodrigues Nascimento   +4 more
doaj   +1 more source

Mycophenolate Mofetil Treatment Reduces the Risk of Treatment Escalation Due to Vascular Complications in Limited Cutaneous Systemic Sclerosis: Emulation of a Target Trial From the Italian Rheumatology Society SPRING Registry

Arthritis Care &Research, EarlyView.
Objective Mycophenolate mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon because of the lower fibrotic burden and the predominance of vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis, Gerlando Natalello, Rossella De Angelis, Lucrezia Verardi, Dilia Giuggioli, Gianluigi Bajocchi, Lorenzo Dagna, Silvia Bellando‐Randone, Giovanni Zanframundo, Rosario Foti, Fabio Cacciapaglia, Giovanna Cuomo, Alarico Ariani, Edoardo Rosato, Gemma Lepri, Francesco Girelli, Valeria Riccieri, Elisabetta Zanatta, Ilaria Cavazzana, Francesca Ingegnoli, Maria De Santis, Giuseppe Murdaca, Giuseppina Abignano, Giorgio Pettiti, Alessandra Della Rossa, Maurizio Caminiti, Annamaria Iuliano, Giovanni Ciano, Lorenzo Beretta, Gianluca Bagnato, Ennio Lubrano, Maria Ilenia De Andres, Alessandro Giollo, Cosimo Bruni, Martina Orlandi, Marco Fornaro, Marta Saracco, Cecilia Agnes, Pier Giacomo Cerasuolo, Gabriella Alonzi, Edoardo Cipolletta, Federica Lumetti, Amelia Spinella, Luca Magnani, Corrado Campochiaro, Giacomo De Luca, Veronica Codullo, Elisa Visalli, Carlo Iandoli, Antonietta Gigante, Greta Pellegrino, Erika Pigatto, Maria‐Grazia Lazzaroni, Franco Franceschini, Elena Generali, Gianna Mennillo, Simone Barsotti, Giuseppa Pagano Mariano, Federica Furini, Licia Vultaggio, Simone Parisi, Clara Lisa Peroni, Gerolamo Bianchi, Enrico Fusaro, Gian Domenico Sebastiani, Marcello Govoni, Salvatore D'Angelo, Franco Cozzi, Fabrizio Conti, Serena Guiducci, Andrea Doria, Carlo Salvarani, Florenzo Iannone, Maria Antonietta D'Agostino, Clodoveo Ferri, Marco Matucci Cerinic, Silvia Laura Bosello, on behalf of the SPRING Italian Registry Collaborators   +77 more
wiley   +1 more source

Regulations of Astrocytic Functions by Endothelins: Roles in the Pathophysiological Responses of Damaged Brains

Journal of Pharmacological Sciences, 2012
The receptors for endothelins (ETs) are classified into the ETA and ETB types. ETB receptors are highly expressed in astrocytes, but pharmacological usages of this receptor are not clarified.
Yutaka Koyama, Shotaro Michinaga
doaj   +1 more source

Role of endothelins on lymphocyte accumulation in allergic pleurisy

, 2000
Endothelins participate in different aspects of inflammatory reactions, including edema formation and eosinophil accumulation in allergic reaction.
M O Henriques, Giles A Rae, Maria das Graças, André L F Sampaio   +3 more
core   +1 more source