Results 21 to 30 of about 4,400 (309)
Endothelin in health and disease
Biomolecules & Biomedicine, 2004 Endothelin is a recently discovered peptide composed of 21 amino acids. There are three endothelin isomers: endothelin -1 (ET-1), endothelin -2 (ET-2) and endothelin - 3 (ET-3).
Emina Nakaš-Ićindić +3 more
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Scientific Reports, 2022 We have previously shown that Kyoto University Substances (KUSs), valosin-containing protein (VCP) modulators, suppress cell death in retinal ganglion cells of glaucoma mouse models through alterations of various genes expressions.
Mami Kusaka +6 more
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Portopulmonary hypertension practice patterns after liver transplantation
Liver Transplantation, EarlyView., 2022 Abstract Portopulmonary hypertension (POPH) is a type of pulmonary arterial hypertension occurring exclusively in those with portal hypertensive liver disease. Liver transplantation (LT) can significantly improve outcomes. Current guidelines counsel against immediate adjustments to targeted therapy after LT and suggest routine echocardiography as ...
Arun Jose +3 more
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Endothelin and restenosis [PDF]
Cardiovascular Research, 1998 Time for primary review 31 days Percutaneous transluminal angioplasty (PTCA) was first introduced into the therapy of patients with coronary artery stenosis in the late seventies [1]. In the two decades since, this method has become standard therapy for patients suffering from all forms of coronary artery disease.
M, Kirchengast, K, Münter
openaire +2 more sources
Allergology International, 1996 The role played by the interaction of nitric oxide (NO) and endothelins (ET) in the modulation of airway function, and the modulation of β-adrenergic-mediated bronchodilator responses by ascorbic acid in the presence or absence of endogenous NO induced ...
Hiroshi Kanazawa +8 more
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Endothelin and the podocyte [PDF]
Clinical Kidney Journal, 2012 In the past decade, research has advanced our understanding how endothelin contributes to proteinuria and glomerulosclerosis. Data from pre-clinical and clinical studies now provide evidence that proteinuric diseases such as focal segmental glomerulosclerosis and diabetic nephropathy as well as hypertension nephropathy are sensitive to treatment with ...
Barton M, Tharaux PL
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Insights into Endothelin-3 and Multiple Sclerosis
Biomolecular Concepts, 2020 Endothelins are powerful vasoconstrictor peptides that play numerous other roles. Endothelin-1 (ET1) is the principal isoform produced by the endothelium in the human cardiovascular system.
Monti Lucia +2 more
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Pharmacological Potential of Endothelin Receptors Agonists and Antagonists
Acta Medica, 2005 Endothelins are potent predominantly vasoconstricting agents that act as local autocrine and paracrine mediators. Endothelin-1 is the most potent and sustained vasoconstrictor and pressor substance yet identified.
Jiří Patočka +3 more
doaj +1 more source
Endothelins in breast tumour cell invasion
, 2005 Endothelins are a family of small, structurally related, vasoactive peptides that have a great number of physiological roles in many tissues. The 'endothelin axis' consists of three 21 amino acid peptides (ET-1, ET-2 and ET-3), two G-protein-coupled ...
Grimshaw, M J
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Early survival factor deprivation in the olfactory epithelium enhances activity-dependent survival
Frontiers in Cellular Neuroscience, 2013 The neuronal olfactory epithelium undergoes permanent renewal because of environmental aggression. This renewal is partly regulated by factors modulating the level of neuronal apoptosis.
Adrien eFrançois +17 more
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