Results 21 to 30 of about 37,353 (347)

Truncated human endothelin receptor A produced by alternative splicing and its expression in melanoma [PDF]

, 1998
In this study, reverse transcriptase polymerase chain reaction was used to amplify human endothelin receptor A (ETA) and ETB receptor mRNA. A truncated ETA receptor transcript with exons 3 and 4 skipped was found.
Berry, PA, Burchill, SA, Carter, ND, Jeffery, S, Kaski, JC, Zhang, YF   +5 more
core   +1 more source

Endothelin in health and disease

Biomolecules & Biomedicine, 2004
Endothelin is a recently discovered peptide composed of 21 amino acids. There are three endothelin isomers: endothelin -1 (ET-1), endothelin -2 (ET-2) and endothelin - 3 (ET-3).
Emina Nakaš-Ićindić, Asija Začiragić, Almira Hadžović, Nešina Avdagić   +3 more
doaj   +1 more source

Insights from Amphioxus into the Evolution of Vertebrate Cartilage [PDF]

, 2007
Central to the story of vertebrate evolution is the origin of the vertebrate head, a problem difficult to approach using paleontology and comparative morphology due to a lack of unambiguous intermediate forms. Embryologically, much of the vertebrate head
A Beverdam, AJ Barlow, AK Wenke, AL Rychel, AL Rychel, C Gans, C Tribioli, CA Ettensohn, CA Yoshida, CT Miller, CT Miller, CV Baker, D Meulemans, D Meulemans, D Meulemans, D ten Berge, Daniel Meulemans, DM Bell, DW McCauley, FS Jones, G Amore, G Zhang, GF Couly, GJ Zhang, H Rahr, H Wada, I Rodrigo, J Azariah, J Mallatt, J Walshe, J Wilson, Jean-Nicolas Volff, JK Yu, JR Martinez-Morales, JR Stone, JS Kang, K Soo, K Yasui, LA Lettice, M Cheung, Marianne Bronner-Fraser, MD Stokes, MV Flores, ND Hopwood, P Smits, Q Zhao, R Meech, RF Spokony, RG Northcutt, S Bruneau, S Perez-Alcala, SA Tahtakran, SH Settle, V Lefebvre, V Lefebvre, WR Jeffery, YL Yan, YL Yan   +57 more
core   +4 more sources

Endothelin and endothelin antagonists in chronic kidney disease [PDF]

Kidney International, 2014
The incidence and prevalence of chronic kidney disease (CKD), with diabetes and hypertension accounting for the majority of cases, is on the rise, with up to 160 million individuals worldwide predicted to be affected by 2020. Given that current treatment options, primarily targeted at the renin-angiotensin system, only modestly slow down progression to
Kohan, Donald E., Barton, Matthias
openaire   +2 more sources

Portopulmonary hypertension practice patterns after liver transplantation

Liver Transplantation, EarlyView., 2022
Abstract Portopulmonary hypertension (POPH) is a type of pulmonary arterial hypertension occurring exclusively in those with portal hypertensive liver disease. Liver transplantation (LT) can significantly improve outcomes. Current guidelines counsel against immediate adjustments to targeted therapy after LT and suggest routine echocardiography as ...
Arun Jose, Elizabeth J. Kopras, Shimul A. Shah, Jean M. Elwing   +3 more
wiley   +1 more source

Involvement of endothelins in neuroprotection of valosin-containing protein modulators against retinal ganglion cell damage

Scientific Reports, 2022
We have previously shown that Kyoto University Substances (KUSs), valosin-containing protein (VCP) modulators, suppress cell death in retinal ganglion cells of glaucoma mouse models through alterations of various genes expressions.
Mami Kusaka, Tomoko Hasegawa, Hanako Ohashi Ikeda, Yumi Inoue, Sachiko Iwai, Kei Iida, Akitaka Tsujikawa   +6 more
doaj   +1 more source

The effect of ascorbic acid on β-adrenergic-mediated bronchodilator responses in the presence of endogenous nitric oxide

Allergology International, 1996
The role played by the interaction of nitric oxide (NO) and endothelins (ET) in the modulation of airway function, and the modulation of β-adrenergic-mediated bronchodilator responses by ascorbic acid in the presence or absence of endogenous NO induced ...
Hiroshi Kanazawa, Takashi Kawaguchi, Hiroshi Kamoi, Seiichi Shoji, Tatsuo Fujii, Shinzoh Kudoh, Kazuto Hirata, Naotsugu Kurihara, Junichi Yoshikawa   +8 more
doaj   +1 more source

Endothelin XII

Life Sciences, 2012
Following the initial description of endothelium-dependent vasoconstriction in the early 1980s, it has been exactly 25 years since efforts to identify the sequence of the endothelin gene and peptide began in May 1987, work which resulted in a landmark paper submitted to Nature in December 1987 and published on March 31, 1988.
Yanagisawa, M, Masaki, T, Vanhoutte, PM, Barton, M   +3 more
openaire   +4 more sources

Endothelin receptor antagonists for the treatment of pulmonary artery hypertension [PDF]

, 2012
AimsThe demonstration that endothelin production is upregulated in pulmonary artery hypertension (PAH) served as the rationale for developing endothelin-receptor antagonists (ERAs) as a treatment for PAH.
Komaromy, David, Krasnikov, Victor V, Monréal Santiago, Guillermo, Otto, Sijbren, Stuart, Marc C A, Tezcan, Meniz   +5 more
core   +1 more source

Mathematical modeling of collagen turnover in biological tissue [PDF]

, 2012
The final publication is available at Springer via http://dx.doi.org/10.1007/s00285-012-0613-yWe present a theoretical and computational model for collagen turnover in soft biological tissues. Driven by alterations in the mechanical environment, collagen
Kuhl, Ellen, Martínez, Miguel Àngel, Peña, Estefania, Sáez Viñas, Pablo   +3 more
core   +2 more sources