Cell and Gene Therapy in Equine Ocular Disease
ABSTRACT Equine ocular disease is common and often challenging to treat using traditional methods. This has led to the development of new therapies. Like human medicine, veterinary medicine is adopting cellular and gene therapy as innovative approaches. Equine ocular disease is a particularly promising area for these techniques.
Kimberly A. S. Young +2 more
wiley +1 more source
Early Transcriptomic and Pathologic Changes of Col8a2 Mutant Fuchs Endothelial Corneal Dystrophy. [PDF]
Zhao X +9 more
europepmc +1 more source
CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang +2 more
wiley +1 more source
A Case of Distinctive Corneal Opacity Following Ciliary Sulcus Ahmed Tube Insertion in a Patient With Glaucoma Associated With Atopic Dermatitis. [PDF]
Ida C +4 more
europepmc +1 more source
Implantable Drug Delivery Systems for Skeletal Muscles and Eyes
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov +8 more
wiley +1 more source
Layer-Specific Proteomic Profiling of the Human Cornea Reveals Insights Into Structure and Biological Function. [PDF]
Schadwinkel HM +10 more
europepmc +1 more source
Comprehending the Membrane Properties for Emulation in Organs‐on‐a‐Chip
The advent of organ‐on‐chip models allows closer emulation of in vivo conditions, leading to effective, less costly, and specific drugs. Although a number of membrane‐based on‐chip models exist, better emulating functional models need to be devised for organ simulations.
Tanmayee Makarand Sathe +1 more
wiley +1 more source
Longitudinal In Vitro Assessment of the Optical Transparency of Preserved Pre-Descemet Layer in the Absence of Corneal Endothelium. [PDF]
Busin M +6 more
europepmc +1 more source
ABSTRACT Living beings are persistently challenged by stress. Stress can be induced by internal stressors and external stressors. External stressors, including radiation, heat, heavy metals, nutritional imbalances, infections, and psychological stress, can induce protein denaturation, leading to misfolded or aggregated proteins.
Paka Sravan Kumar +5 more
wiley +1 more source
Overcoming Opacity: The Role of Intraoperative OCT in Complex Corneal and Anterior Segment Surgery. [PDF]
di Geronimo N +4 more
europepmc +1 more source

