Results 21 to 30 of about 266,603 (335)
Cells, 2019 Crohn’s disease (CD) is a chronic inflammatory condition that can affect different portions of the gastrointestinal tract. Lymphatic drainage was demonstrated to be dysfunctional in CD pathogenesis, ultimately causing the failure of the resolution ...
Federica Ungaro +13 more
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Culturing Purifies Murine Lymph Node Lymphatic Endothelium [PDF]
Lymphatic Research and Biology, 2014 Lymph node (LN) lymphatic sinuses transport lymph, cells, and antigens from the periphery through the LN. The lymphatic endothelium lining these sinuses appears to be an important contributor to the lymph node immune response. It has been challenging to obtain sufficient LN lymphatic endothelial cells for investigation of their functions, as they are ...
Kimberly L. Jordan-Williams +1 more
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Symposium on the development and structure of the lymphatic system. III. Further evidence on the origin of the lymphatic endothelium from the endothelium of the blood vascular system [PDF]
The Anatomical Record, 1908 n ...
F. Sabin
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Direct specification of lymphatic endothelium from non-venous angioblasts
bioRxiv, 2022 The lymphatic vasculature is essential for tissue fluid homeostasis, immune cell surveillance and dietary lipid absorption, and has emerged as a key regulator of organ growth and repair1.
Irina-Elena Lupu +10 more
semanticscholar +1 more source
Oncogenesis, 2021 Lymphatic metastasis represents the main route of tumour cell dissemination in oral squamous cell carcinoma (OSCC). Yet, there are no FDA-approved therapeutics targeting cancer-related lymphangiogenesis to date.
Sini Karinen +9 more
semanticscholar +1 more source
Frontiers in Physiology, 2021 The lymphatic system is a vascular system comprising modified lymphatic endothelial cells, lymph nodes and other lymphoid organs. The system has diverse, but critical functions in both physiology and pathology, and forms an interface between the blood ...
Zarah B. Tabrizi +4 more
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Cancer Science, 2021 Lymphangiogenesis is a key process in cancer development and metastasis. Lymphatic vessel endothelial hyaluronan receptor 1 (LYVE‐1) is a widely used marker for lymphatic endothelial cells (LEC), which also mediates immune and cancer cell migration ...
Sini Karinen +3 more
semanticscholar +1 more source
Lymphatic Clearance of Immune Cells in Cardiovascular Disease
Cells, 2021 Recent advances in our understanding of the lymphatic system, its function, development, and role in pathophysiology have changed our views on its importance. Historically thought to be solely involved in the transport of tissue fluid, lipids, and immune
Christophe Ravaud +4 more
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The Lymphatic Endothelium in the Context of Radioimmuno-Oncology
Cancers, 2022 The study of lymphatic tumor vasculature has been gaining interest in the context of cancer immunotherapy. These vessels constitute conduits for immune cells’ transit toward the lymph nodes, and they endow tumors with routes to metastasize to the lymph nodes and, from them, toward distant sites.
Lucía Suárez +2 more
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The Journal of Cell Biology, 2003 The lymphatic microvasculature is uniquely adapted for the continuous removal of interstitial fluid and proteins, and is an important point of entry for leukocytes and tumor cells. The traditional view that lymphatic capillaries are passive participants in these tasks is currently being challenged.
Mihaela Skobe, Michael S. Pepper
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